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W Publig

Publications and source records attributed to W Publig.

6 recordsLinked to original sources
PubMed1994

Non-steroidal anti-inflammatory drugs (NSAID) cause gastrointestinal ulcers mainly in Helicobacter pylori carriers.

In a prospective study from August to the end of December 1992, all patients with endoscopically confirmed gastric or duodenal ulcers were examined for the presence of H. pylori infection by means of an antibody blood test and gastric biopsy. After a detailed history had been taken the patients were divided into two groups. Group I (n = 40) was made up of patients taking NSAIDs. Group II (n = 42) consisted of non-NSAID patients. A control group was formed of NSAID patients with no marked intestinal complaints and the absence of ulcers confirmed on endoscopy (group III, n = 38). H. pylori infection was identified in 33 out of 40 patients in group I (82.5%), 37 out of 42 patients in group II (88.0%), and only 17 out of 38 cases in group III (44.7%). Bleeding complications were evidently associated with the use of NSAIDs: 12 patients in group I (30%), as opposed to only 2 patients in group II (5%) showed bleeding from an ulcer on endoscopy. It would, thus, appear that ulcers frequently arise as a result of H. pylori infection, whereas bleeding complications of ulcers are associated mainly with NSAID intake. The QuickVue antibody test and biopsy results concurred in 81.8% of cases. Because of its high sensitivity the QuickVue test could become a very important risk assessment tool when planning long-term NSAID therapy. H. pylori eradication ought perhaps be considered before the start of NSAID treatment.

Aged↗
PubMed1988

[Electronic data processing-assisted documentation in gastroenterologic endoscopy. Simultaneous archiving and report].

A new computer programme for documentation in endoscopy is presented. Separate numeric codes each for main diagnosis, histology, type of complication and therapeutic management provide flexibility for every kind of endoscopic investigation. The ICD Veska Code, a code of group diagnosis, was chosen for the main diagnosis and expanded by one digit. This allows the addition of topical and/or other differential diagnostic features to the main diagnosis. As a result we have a code with typical endoscopic diagnostic patterns. The system provides a direct printout without the requirement of any further provisions. The numeric code ensures simple statistic evaluation of all important data.

Endoscopy↗
PubMed1986

[Effect of endoscopic hemostasis using an electrohydrothermic probe on the course of hemorrhaging stomach and duodenal ulcers].

This is a report on the application of the EHT-probe in 94 patients with bleeding ulcers (stomach and duodenum) during a period of three years (1981-1983). The effect upon the course of disease and mortality is discussed. A permanent termination of bleeding could be achieved in 71% of cases (59 patients of a total of 94 patients). The data are compared with a former period (1978-1980) without the possibility for endocopic treatment of bleeding ulcers. By using the EHT-probe less emergency operations were performed (19.1% compared to 36.4 during the earlier period). The over-all mortality decreased from 27.3% (1978-1980) to 17.7% (1981-1983). These favourable results are promoting the active intervention by endoscopic treatment with a electro-hydrothermic probe.

Duodenal Ulcer↗
PubMedDate not supplied

[Prevention of ossification after total hip endoprosthesis with indomethacin and its effect on gastric mucosa].

The administration of indomethacin as a prophylactic against heterotopic ossification following the implantation of total hip-joint endoprosteses entails the risk of gastrointestinal side-effects. A prospective randomized study set out to determine the effectiveness of ranitidine and sucralfate as a secondary treatment for the protection of the stomach. Comparison with a placebo group monitored at the same time confirmed the efficacy of both medicaments. Both ranitidine (2 x 150 mg) and sucralfate (4 x 1 g) were able to prevent the occurrence of ulcers of the mucous membrane of both stomach and duodenum. Thanks to postoperative prophylactic treatment with indomethacin (2 x 50 mg for 3 weeks), there were no serious ossifications (degree II or III according to Arqu).

Adult↗