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Biomedical subjects

W Pumberger

Publications and source records attributed to W Pumberger.

33 records · Page 2Linked to original sources
PubMed1999

Short-bowel syndrome associated with subtotal necrosis of small intestine after rectal trauma.

We report on a 4-year-old girl who experienced rectal trauma during swimming, sitting on an uncovered draining valve in the swimming pool. This resulted in a powerful suction effect on her rectum, followed by rupture of the sigmoid colon and evisceration of the small intestine. Laparotomy showed a near complete necrosis of the small bowel because of thrombotic lesions and wall lacerations of the superior mesenteric artery (SMA). A subtotal bowel removal associated with a jejuno-ileostoma was carried out, a total length of about 35 cm of the small intestine could be left in situ. Parenteral nutrition was stopped after eight months. At the moment defecation takes place 2-3 times a day, growth and weight gain are quite normal.

Accidents↗
PubMed1998

Transient pseudohypoaldosteronism in obstructive renal disease.

The cases of two patients with transient pseudohypoaldosteronism due to an up to this point unrecognized obstructive renal disease are reported. Both girls presented with a severe salt-losing episode in early infancy mimicking congenital adrenal hyperplasia. Extensive endocrinologic work-up revealed markedly elevated plasma-aldosterone levels. Clinical and laboratory data were consistent with transient pseudohypoaldosteronism. Sonographic and radiological investigation showed in both children a vesicoureteral reflux of differing grades. After therapy of the electrolyte-imbalance and recovery, one of the children required surgical treatment of vesicoureteral reflux.

Diagnosis, Differential↗
PubMed1998

Appendicitis in children with a ventriculoperitoneal shunt.

The presentation of an acute abdomen in children with a ventriculoperitoneal shunt requires skillful diagnostic workup. Apart from complications caused by the shunt, primary abdominal pathological conditions must be taken into consideration, particularly in the older child. A series of 6 children with a ventriculoperitoneal shunt had to be treated surgically for appendicitis. Their medical records were analyzed retrospectively. Despite difficulties with the initial diagnosis, the time from admission to final diagnosis and operation was relatively short. An accurate history, careful evaluation of the clinical signs and, above all, ultrasound of the abdomen were helpful in decision making. During the operation the shunts were left in place. Only 1 patient developed a cerebrospinal fluid pseudocyst in the early postoperative period, which made a conversion into a ventriculoatrial shunt necessary. No ascending infection occurred, even when the abdominal tip of the shunt came in close contact with the focus of inflammation. An acute abdomen due to shunt infection should be managed conservatively and by removal of the shunt from the abdomen, thus avoiding an unnecessary laparotomy. On the other hand, a primary intraabdominal disease requires surgical treatment, during which the shunt system can be left in place.

Abdomen, Acute↗
PubMed1992

BCG osteomyelitis as a rare cause of mediastinal tumor in a one-year-old child.

A one-year-old child with BCG osteomyelitis of the upper spine is reported. The child was admitted because of viral infections of the upper respiratory tract. A lateral x-ray examination of the lung showed what was thought to be a mediastinal tumor. The preoperative diagnostic problems are discussed, because the etiology in our case was unknown until the histological report arrived. The knowledge of the complication, of osteomyelitis after vaccination, is small although the first case was published more than 40 years ago. Since then about 300 cases have been reported in the literature. The disease is seen in the first five years of life in otherwise healthy children. Most cases are localized near the epiphysis of the long bones. A localization in the spine, as described in our case, has been published only three times before. The highest frequency of BCG osteomyelitis is reported in Finland and Sweden with about 40 cases per 1 million vaccinations.

Diagnosis, Differential↗
PubMed1989

Implantation of a silastic balloon for reduction of radiation injuries of the bowel in two children with neuroblastoma.

Two children with stage IV neuroblastoma died from severe reactions of the bowel due to radio-chemotherapy. This led to the suggestion of protecting the bowel by implantation of a silastic balloon to push the bowel away from the treatment volume. This procedure was tried in two children with stage IV neuroblastoma and resulted in excellent tolerance of the high-dose radiotherapy.

Abdominal Neoplasms↗
PubMed1989

Surgical treatment of bilateral Wilms' tumours with special reference to second operations in metachronous disease.

We report on six patients with bilateral Wilms' tumours (among them one pair of siblings) who underwent surgery within a period of 20 years. Wilms' tumours appeared synchronously in three patients and successively in the other three. Case reports are given for three of the six patients. The tumours have a remarkable multilocular appearance, indicating a multilocular genesis. In this context, the phenomenon of nephroblastomatosis is discussed. In addition to surgical treatment, aggressive conservative therapy should be employed, particularly with metachronous disease and the resulting acquired solitary kidney in these patients.

Child, Preschool↗
PubMed1976

Increased sister chromatid exchange events in the human late replicating X.

Human female blood cultures were labeled with BrdU for detecting sister chromatid exchanges (SCEs) by the Hoechst 33258 fluorescence technique. Late labeling with 3H-thymidine and autoradiography allowed the identification of the late replicating X. The mean number of SCEs in the cells was 13. The isopycnotic X showed an exchange frequency according to its relative length in the karyotype; in the late replicating X a doubled number of SCE events was observed.

Chromatids↗
PubMedDate not supplied

Sonographic diagnosis of intussusception of the appendix vermiformis.

We present 2 cases of intussusception of the appendix vermiformis (IAV) in children. Sonographic examination demonstrated a lead point within a characteristic multiconcentric ring sign, and longitudinal sonograms showed the inverted appendix protruding into the cecal lumen. A contrast-enema study, using a water-soluble contrast medium, was performed in each case, and a "coiled-spring" sign or "spiral shell" appearance confirmed the diagnosis. A surgical reduction of the appendix and an appendectomy were performed in each case.

Appendectomy↗
PubMedDate not supplied

Intraabdominal extralobar pulmonary sequestration exhibiting cystic adenomatoid malformation: prenatal diagnosis and characterization of a left suprarenal mass in the newborn.

An intraabdominal extrathoracic pulmonary sequestration (IEPS) was detected by prenatal ultrasound in a fetus of 19 weeks' gestation. The well-defined echogenic mass, including multiple cystic areas, was located in the left suprarenal region. Knowledge of the characteristic ultrasound appearance helped to differentiate between neuroblastoma and IEPS before surgical treatment. Histologic examination showed an association between IEPS and features of cystic adenomatoid malformation type 2.

Bronchopulmonary Sequestration↗
PubMedDate not supplied

Fatal neonatal Salmonella enteritidis sepsis.

A case history of a fatal neonatal infection caused by Salmonella enteritidis group D is reported. The baby deteriorated rapidly at 24 hours after birth with clinical signs and symptoms of an acute abdomen. Bloody diarrhea led to a tentative diagnosis of midgut volvulus or necrotizing enterocolitis. Autopsy and bacteriologic investigation revealed sepsis by S. enteritidis group D. The same organism was found in cultures taken from stool and vaginal swabs from the mother. This clearly confirmed transmission of the infection during delivery.

Bacteremia↗
PubMedDate not supplied

[Intratesticular epithelial cyst in an infant].

We report on a 7-month-old boy with a simple cyst of the testis who was treated with excision and testicular preservation. Benign testicular tumors are more common in children than in adults (30%). Ultrasound may permit identification of benign testicular lesions. As simple cysts are isolated benign entities they may be treated by testisparing surgery.

Adult↗