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Biomedical subjects

W R Ade

Publications and source records attributed to W R Ade.

4 recordsLinked to original sources

Turnover procedure.

Sternal turnover can be considered an orthotopic bone transplantation in reverse position. It yields immediate stability of the chest and good cosmetic results. Procedures using "pedicled plastrons" (rectal muscles, internal mammary arteries) have been reported; a large series of 300 cases, however, shows satisfying results with free grafts. Technetium-99m isotope studies yielded visualization of the plastron 1 year after sternal turnover. After redo-operations, histopathologic studies gave nearly normal sternal bone marrow findings.

Bone Transplantation↗

Autoregulated extra- and intracorporeal pump system for perfusion.

Recent statistics indicate that one serious event occurs once in every 300 perfusions. We have devised a cybernetic approach using photosensors and pressure sensors at critical points of the circuit which should allow feedback regulation of the bypass according to the changes in venous return. In order to avoid overtransfusion, left atrial pressure control is employed. This also enables automatic weaning and facilitates partial bypass. In the clinical setting a test system proved to be accommodated to prevent gross air contamination of the arterial line. Based on vast clinical experience with the conventional method of extrapulmonary circulation, the logical extension of this work will be the development of a compact pump oxygenator utilizing hemofilters, the pump portion of which can be temporarily implanted until the cardiac function has been restored. It is autoregulated and, if the need arises, controlled by the anesthetist, one of whose primary concerns will be physiological perfusion.

Adult↗

New wire suture for sternal fixation.

A new sternal fixation wire, 60 cm in length, was tested clinically. The center portion of the wire is 30 cm in length and 0.8 mm in diameter, while the two end portions of the wire are 15 cm in length and 0.3 mm in diameter. A drill or gimlet with a small hole in the tip was employed to bore a hole in the sternum. The thin ends of the wire were inserted into the hole of the drill, making it easier to pass the wire through the sternal bone. We have found wire penetration through the sternum to be simpler and less traumatic using this technique.

Humans↗