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Biomedical subjects

W R Webster

Publications and source records attributed to W R Webster.

At least 55 records · Page 3Linked to original sources

Granulomatous lesions in pigs associated with the use of an oil-based erysipelas vaccine.

Severe granulomatous lesions in cervical muscles and lymph nodes, associated with the use of an oil-based erysipelas vaccine, caused considerable economic loss at slaughter in 1400 pigs from the one herd. The condition was reproduced experimentally using the same vaccine, and in a less severe form with another commercially available oil-based erysipelas vaccine.

Animals↗

Inferior colliculus. I. Comparison of response properties of neurons in central, pericentral, and external nuclei of adult cat.

The responses of 150 units in the central (ICC), pericentral (ICP), and external nuclei (ICX) of the inferior colliculus of the anesthetized cat were studied in relation to their tuning characteristics and binaural responses to tonal stimuli. Units in ICC were characterized by sharp tuning and binaural responses, while those in ICP and ICX were frequently very broadly tuned with a poorly defined best frequency. Nonetheless, in the latter nuclei a tendency existed for tonotopic organization to occur with high frequencies located externally and low frequencies at the margins of the central nucleus. Tuning measurements were hampered by the common occurrence of habituation in the discharges of single units in ICP and, to a lesser extend, ICX. The majority of units in ICP could be differentiated from those in ICX by their monaural input. Speculations were advanced linking anatomical cell types to physiological responses in the three nuclei and into the possible functional significance of the different behavior of units to tonal stimuli.

Animals↗

Auditory habituation and barbiturate-induced neural activity.

The finding that barbiturates abolish habituation decrements in auditory evoked potentials has been interpreted as being caused by removal of the influence of the reticular formation. Similar changes in the medial geniculate are produced by barbiturates without any intervening habituation, suggesting that refractory processes have been confused with habituation.

Animals↗