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W Rödl

Publications and source records attributed to W Rödl.

67 records · Page 4Linked to original sources

[Importance of the preparation for the double contrast examination of the colon (author's transl)].

In a consecutive series of 299 routine double-contrast studies of the colon, X-ray films were examined prospectively for remaining stool in the colon. In 47%, the radiological diagnosis was restricted by stool. There was no statistic significant difference in patient's sex and age, and also none in the abnormal radiological findings compared to the group with good cleaning. The results elucidate important steps in preparing the patient for a clean colon: (1) the necessity of the radiologist being active in the preparation. (2) Written instructions and explanations must be given to every patient. (3) Regular motivation of the physicians and nursing teams is essential. Only a clean colon ensures early detection of colorectal polyps and efficient prevention of colorectal cancer.

Colon↗

[Cystic degeneration of the adventitia of the popliteal artery (author's transl)].

Cystic degeneration of the adventitia of the popliteal artery is a rare clinico-angiographic diagnosis in the chronic ischaemia syndrome of the lower extremity. If the three cardinal signs occur concomitantly, namely, intermittent ischaemia syndrome, unilocular manifestation near the joint and clearly limited filling defect in the arteriogram, diagnosis can be made with a high measure of certainty. Among our angiographically examined patients, we observed, in the course of one year, three male patients who presented the full picture of the disease with regard to clinic, localisation and angiographic findings. Intraoperatively it was not possible to establish a connection between adventitia cyst and neighbouring articular capsule; this applies, in fact, to all our cases. Histologically we found in one case, in the hollow spaces of the adventitia, an indication of the possible existence of a synovial recess, so that the scattering of mucine-secreting endothelium of the joint into the vascular adventitia is again brought up for discussion.

Aged↗

[Gardner's syndrome. three patients with varying manifestations (author's transl)].

Fully developed Gardner's syndrome is characterised by the triad of intestinal polyposis, osteomas and multiple soft tissue tumours. Absence of any one of these manifestations results in a bisymptomatic form. We describe three patients, one woman and two men aged 40, 46 and 51 years. In two patients the triad was fully expressed, but with varying organ involvement. The third patient was of the bisymptomatic type with osseous and intestinal lesions.

Adult↗

[Duplication of the gallbladder. A rare anomaly, more often a diagnostic error (author's transl)].

A case of true duplication of the gallbladder and three cases with roentgen signs simulating duplication are reported. In true duplication the diagnosis was made by routine cholecystography which showed a double gallbladder with ductular shape. In three cases the cause for an incorrect diagnosis by cholecystography were an ampullary right renal pelvis visualized by heterotopic renal excretion of the contrast medium, a short loop of the first and second part of the duodenum and a diverticulum at the outer border of the duodenum.

Aged↗

[Diagnostic and therapeutic aspects of early (superficial) gastric carcinoma: a retrospective analysis of 60 cases (author's transl)].

Among 947 patients operated on for gastric carcinoma between 1961 and 1976 there were 60 with early (superficial) gastric carcinoma. All but two patients consulted their doctor for diverse complaints. In one third of them treatment was delayed for a year or longer. In 26 of the 64 cancer foci it was limited to the mucosa. The correct diagnosis was made radiologically in 60%, gastroscopically in 70%. Selective endoscopic biopsy increased accuracy to 90%. The remaining false-negative findings occurred in the ulcerative form, which was the most frequent one. Improved radiological techniques (double-contrast) and obligatory gastroscopy with biopsy increased the relative proportion of early (superficial) carcinoma from under 4% in 1961 to 15%. The diagnosis of this type of carcinoma can be made only by careful histological study of the surgical specimens. Here as elsewhere in the surgery of carcinoma, multicentricity (in 5%) and possible lymph node metastases (10-20%) must be taken consideration in the surgical management.

Adult↗

Intralymphatic interleukin-2 in combination with zidovudine for the therapy of patients with AIDS.

In a pilot study the safety and therapeutic effects of an immunostimulatory intralymphatic treatment with natural human interleukin-2 (IL-2) in combination with zidovudine were evaluated in nine patients with AIDS. Therapy with IL-2 consisted of one subcutaneous injection of 0.1 microgram/kg IL-2, followed by four intralymphatic IL-2 infusions of 0.1 microgram/kg each within a period of up to 15 days. Enlargement of lymph nodes was seen in six and a transient increase of CD4 cells in five out of nine persons in association with the IL-2 therapy. An increase of HIV p24-antigenemia was observed only in the two patients in whom zidovudine dosage had to be reduced because of side effects. Moderate clinical side effects occurred in eight of the nine patients. Four patients developed zidovudine associated anemia. Six participants showed a favourable course of disease with survival of 25 to 54 months (median 30 months) despite a previous diagnosis of manifest AIDS before IL-2 therapy. This pilot study demonstrates that a combination therapy with intralymphatic IL-2 and zidovudine can induce positive immunomodulatory effects, even in the presence of manifest AIDS. Further studies should explore the tolerability and effects of a prolonged therapy with IL-2 in combination with a more potent antiviral drug combination therapy.

Acquired Immunodeficiency Syndrome↗