Biomedical subjects
Publications and source records attributed to W Russ.
A demand-controlled alfentanil bolus technique, which proved to be a safe and easy-to-handle method in 22 neurosurgical operations of mean and longer duration, is described. In the case of these not very painful procedures the use of more complicated time-controlled bolus or infusion techniques does not seem to be necessary.
After injection of etomidate during surgery for herniation of an intervertebral disk an anaphylactoid reaction occurred. Generalized erythema, severe urticaria, and rise in heart rate and blood pressure drop were observed. After treatment with an antihistaminic and a corticosteroid the phenomenons completely disappeared within 45 minutes.
Visual evoked potentials (VEP) were monitored intraoperatively in 35 urological patients during modified neuroleptanalgesia. Control measurements were made in 18 awake, premedicated patients prior to induction of anesthesia. The latencies of the negative peaks (designed n1, n2, n3) increased significantly (p = 0.001) during anesthesia: n1 from 50,6 ms to 57,1 ms, n2 from 80 ms to 89,4 ms, n3 from 124,5 ms to 139,6 ms, no significant change in amplitude was seen. Changing paCO2 in the range from 20 mmHg to 50 mmHg during controlled ventilation did not affect latencies and amplitudes of visual evoked potentials (n = 10 patients). These influences of neuroleptanalgesia must be considered when recording visual evoked potentials intraoperatively during neurosurgical procedures (aneurysm-, pituar gland surgery) for monitoring optic nerve function.
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