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Biomedical subjects

W S Anderson

Publications and source records attributed to W S Anderson.

8 recordsLinked to original sources
PubMed2006

Plasticity of pain-related neuronal activity in the human thalamus.

Strokes and other forms of injury to the central nervous system cause changes in function because of the injuries themselves and indirectly because injuries cause expression of neural plasticity. Studies in humans undergoing neurosurgical procedures for implantation of electrodes for deep brain stimulation and for making lesions in the brain have contributed understanding of both normal and abnormal functions of the somatic sensory system. This chapter will specifically discuss the reorganization of the ventral caudal (Vc) sensory nucleus of the thalamus that occurs in connection with pain conditions after strokes and spinal cord injuries. It is shown that pain is associated with expression of neural plasticity that alters maps of noxious and innocuous stimulation in the thalamus and affect processing of sensory information. Results from studies of neural activity in the thalamus in humans will be compared with results from animal studies.

Brain Injuries↗
PubMed1983

Fat cow syndrome in a British dairy herd.

The fat cow syndrome developed over a two year period in a 100 cow dairy herd following overfeeding in late lactation and the dry period. It was characterised clinically by a high incidence of parturient paresis and chronic unresponsive ketosis in early lactation. The reproductive performance of the herd was poor throughout this period, with extended calving indices confirming a suggested link between fatty liver and infertility.

Animals↗
PubMed1967

A re-evaluation of the place of major extirpation in the management of patients with metastatic mammary carcinoma.

Clearly defined indications for major extirpation procedures in metastatic mammary carcinoma are lacking. A reassessment of experience with 222 patients (133 after adrenalectomies and 89 after hypophysectomies) was therefore undertaken. This experience has changed our previous opinions that such procedures should be used only at the end of a sequential program of treatment.It is now felt that extirpation is only contraindicated in menopausal women with a duration of disease less than two years or when there is symptomatic disease of vital organs. Otherwise, early extirpation is recommended. When vital organ involvement is recognized in the asymptomatic stage or when screening of premenopausal women by castration indicates continuing hormonal dependency, then early extirpation is indicated.Both the qualitative and the quantitative responses achieved exceed those obtained by other measures when widely disseminated disease is present. The objective remission rate (34% after adrenalectomy and 19% after hypophysectomy) for longer than six months is worth while.

Adenocarcinoma, Mucinous↗