Biomedical subjects

W S Botha

Publications and source records attributed to W S Botha.

21 records · Page 2Linked to original sources

PubMed1978

[Pathological changes in the tendons of the pectineal muscles in a case of canine hip dysplasia (author's transl)].

This report gives radiological and pathological evidence of bilateral ossification of the aponeurotic tendons of insertion of the pectineal muscles in a dog. This was associated with a severe grade 3 hip dysplasia of which the pathological changes are described. The ossification of the tendons is considered to have resulted from excessive and continous tension of the pectineus muscles. Various aetiological factors are discussed and some substantiation provided for the theory that pathology of the pectineal muscles and their tendons of insertion may be a contributing factor in the pathogenesis of hip dysplasia.

Animals↗

PubMed1978

Light and electron microscopical studies on canine encephalitozoonosis: cerebral vasculitis.

Brain lesions in 2 natural cases of canine encephalitozoonosis were studied by light and electron microscopy. Granulomatous reactions, associated with small vessels and capillaries, partly originated from extensive perithelial cell proliferation which ultimately produced the epithelioid cell component. Diffuse glial reactions apparently occurred in relation to the vasculitis. Lymphoid cells infiltrated the epithelioid and glial cell inflammation. Encephalitozoon in all its reproductive stages was identified as the aetiological agent, and ultrastructurally differentiated from Nosema on the basis that a single nucleus was observed. Viable organisms were present only within endothelial cells. Macrophages containing dead spores were usually seen around parasitized vessels and, less frequently, in the neuropil. Organisms, whether viable or non-viable, were never seen extracellularly at the ultrastructural level. Selected histochemical stains and electron microscopy were used to differentiate between viable and non-viable spores. Vasculitis is demonstrated as the underlying lesion of canine encephalitozoonosis affecting the brain and is suggested to be the basic factor in the pathogenesis of this disease.

Animals↗

PubMed1977

Feline infectious peritonitis in South Africa.

The clinical, clinical pathological and pathological findings in ten natural and two experimental cases of feline infectious peritonitis are described. The literature is reviewed and compared with the findings of these cases. It is concluded that feline infectious peritonitis occurs as a distinct clinical disease entity in domestic cats in the Republic of South Africa.

Animals↗