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W S Tulloch

Publications and source records attributed to W S Tulloch.

11 recordsLinked to original sources
PubMed1978

Recent observations on the ultrastructure of human urothelium. 1. Normal bladder of elderly subjects.

An electron microscopic study of normal bladder urothelium of elderly patients ranging in age from 61 to 82 years has shown the occurrence of unusually thin regions consisting of either one or two layers of undifferentiated cells interspersed between 3--4 cell layers thick regions. A morphometric study has confirmed the existence of a pattern of cytodifferentiation in cells of the thick region. The generally microvillous nature of the luminal surface is attributed to incompletely differentiated cells that have come to occupy the superficial layer. The lack of thickened and/or asymmetric membrane plaques in luminal plasma as well as the dearth of characteristic precursor vesicles in the cytoplasm are also explicable in terms of a failure of normal cell differentiation. It is suggested that the unusual features noted are consequences of tissue ageing rather than prognostic of cancer. There are indications that the aged urothelium may be prone to increased leakiness and the bladder tissues may therefore be at greater risk from urine-borne chemicals and carcinogens.

Aged↗
PubMed1976

Herpes zoster with dysfunction of bladder and anus.

Herpes zoster may give rise to dysfunction of bladder and anus. Mucosal lesions have been reported, and 7 cases are described with retention, loss of sensation, or incontinence. Sacral shingles is associated with sensory loss and flaccid detrusor paralysis. Lumbar shingles may cause retention, and zoster at higher levels can also damage the spinal cord. Recovery is usually complete. The implication for schemes of bladder innervation is discussed.

Aged↗
PubMed1975

Hyperthermic perfusion of the distended urinary bladder in the management of recurrent transitional cell carcinoma.

The clinical and histological changes following hyperthermic perfusion of the distended urinary bladder have been studied in 13 patients with transitional cell carcinoma, persistent after radical radiotherapy. Continuous epidural anaesthesia was necessary to achieve a constant state of bladder relaxation during irrigation of the distended bladder. This form of hyperthermic perfusion of the bladder was effective in arresting uncontrollable haemorrhage from bladder tumours and may be of value in the treatment of this complication. Perfusion at an outflow temperature of 44 degrees C for 4 hours caused tumour necrosis. It was, however, associated with damage to the vasculature of the bladder and frequency of micturition which persisted after mucosal recovery. Perfusion at 43 degrees C also caused tumour necrosis and the after effects were less severe.

Carcinoma, Transitional Cell↗
PubMed1975

Conservative management of renal tuberculosis.

The conservative management of 60 patients suffering from renal tuberculosis is reported. Following chemotherapy, bacteriological conversion to negative was obtained in all patients. 2 patients (3-3%) relapsed due to failure to take adequate treatment. Evidence of ureteric obstruction was obtained in 30 patients (50%)--23 at the time of diagnosis, 6 during treatment and 1 at the time of relapse. Following corticosteroid treatment relief of obstruction was obtained in 72%. Nephrectomy was carried out in 4 patients (6-7%) but in only 1 of these was the operation carried out for reasons which we now consider valid.

Adolescent↗
PubMed1971

Hydrocele.

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Age Factors↗