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Biomedical subjects

W Schiek

Publications and source records attributed to W Schiek.

At least 19 recordsLinked to original sources
PubMed1976

[Bacteriological investigations in radiological clinic (radiographic apparatus, rooms and personnel) (author's transl)].

The importance of X-ray departments as a potential source of infection with hospital organisms was investigated by examining a number of radiographic rooms and comparing these with two private dwellings. It was found that there was a higher incidence of organisms than in private homes, but this was considerably less than on wards. Particularly high numbers of organisms, including pathogenic ones, were found on radiographic apparatus which was inaccessible, and on sponge pillows. Regular disinfection reduced the number of organisms almost to the level of an operating theatre. A visit to the X-ray department does not present a significant risk of infection; nevertheless, hygiene can be markedly improved by appropriate changes in the rooms and by carrying out methods of disinfection.

Communicable Diseases↗
PubMed1975

[Studies on the in vitro formation of antibodies. III. Induction of primary and secondary immune response in vitro].

Peritoneal cells from normal, unimmunized mice (female NMRI, 28-32 gr) produced in vitro primary and secondary immune response after induction with the bacteriophage T2 6 hours or 7 day resp. after establishing the cultures. We confirmed the induction of a primary and secondary immunological response in vitro in the very same culture by the following data: 1. In vivo the donor animals were not in contact with the antigen used. We found neither the phage nor its host E. coli B in the gut of 97 mice investigated and no humoral antibodies against T2. The kinetics of humoral antibody production in vivo by different doses of T2 also showed that there are no related or identical antigen structures incorporated in our animals. 2. The T2 neutralizing activity in the culture medium after the first induction had the sedimentation constant of 19.7 +/- 2.3 S (n = 9) but the activity found after the second induction sedimented with 8.1 +/- 0.7 S (n = 10). 3. The primary activity was more sensitive to mercaptoethanol than the secondary. 4. Complement was bound by the complex T2 + neutralizing activity.

Animals↗