PubMed Health⌕ Search

Biomedical subjects

W Schunk

Publications and source records attributed to W Schunk.

At least 19 recordsLinked to original sources
PubMed1993

A natural rubber drainage tube with antithrombogenic lumen surface.

A drainage tube was made by radiation vulcanization of a high polymeric substance based on natural rubber elastomers. Pentosan polysulphate sodium bound to a carrier substance (synthetic type 4A or 13X zeolite) was incorporated in the drainage tube which was then tested for its anticoagulant properties during perfusion with Tris buffer solution, citrated plasma, and blood, resp. The amount of pentosan polysulphate sodium released from the tube walls during perfusion with human citrated plasma in an open circulatory system was sufficient to exert an anticoagulant effect on the streaming plasma. This effect was corroborated by prolonged thrombin times and by unclottability in case of recalcified plasma samples in thrombelastographic studies. The antithrombogenicity test according to Chandler in a closed circulatory system revealed thrombus formation times (TFT) of more than 24 h (control: TFT = 1-3 min in native blood).

Animals↗
PubMed1989

[Exposure to asbestos dust and asbestosis of employees in a Thüringen rubber industry].

131 exposed people by dust of talc in rubber industry in Thuringia were examined by contrast to a same no examined group of working people. The asbestos in talc did cause in 26 (19.8%) cases of exposed people a pneumoconiosis. The occupational disease was admitted. The time of development was between 20 and 40 years. We can found the chronic bronchitis and demages of ventilation much more in cases long time exposed people and by smokers. The following conclusions are: the renunciation of application of talc with asbestos, measures to fight against dust, the instruction of direction and of working people about the danger of asbestos and the dispensatory care for life.

Adult↗
PubMed1988

Studies on elastomeric materials with incorporated antithrombotics.

Antithrombotically effective drugs (heparin, pentosan polysulphate, streptokinase) were incorporated into elastomeric materials by means of zeolites as carrier. The incorporated antithrombotic agents can be delivered to the surrounding medium. These self-antithrombotic elastomers may be used as tubes to drain off body fluids (catheters, drains, etc.).

Adsorption↗
PubMed1987

[Problems of exposure to organic mercury compounds in pregnancy].

On account of oral intake of mercury by contaminated foodstuff (eggs eaten by pregnant women) due to non-observance of legal decisions increased mercury concentrations in the maternal and infantile blood, in the urine and hair of the mother, in the placenta, the amnion, the cord blood and the breast milk could be proved in comparison to non-exposed pregnant women. Clinical and laboratory-chemical parameters did not show any symptoms of an intoxication in mothers and children. Demands for observance of the legal decisions and avoidance of professional dealing are particularly important for pregnant women.

Female↗
PubMed1982

[New aspects of chronic occupational manganese poisoning].

Wherever workers are professionally exposed to manganese and its compounds, but particularly in brown haematite mills, a chronic occupational manganese intoxication may appear with the picture of an expressed results of own investigations on 45 workers of a brown haematite mill in Thuringia who were exposed to manganic dust during 11 years as well as on manganese patients who were reported shall contribute to the clarification of the question of early diagnosis and differential diagnosis of a manganese intoxication. Attention is paid to functional diagnostic methods (EEG, EMG). On the basis of successes of treatment with the help of a substitution therapy of L-Dopa and amantine hydro-chloride new aspects concerning the pathogenesis of this disease are reported and conclusions for practice are made.

Amantadine↗