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Biomedical subjects

W Seffner

Publications and source records attributed to W Seffner.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Correlations between certain parameters of weight increase, slaughter performance, meat condition and thyroid function in swine for slaughter comparing various boar offspring].

Comprehensive tests were applied to a larger number of pigs for slaughter, all kept under the same conditions and all of known genetic origin. Subjects of testing were pork quality parameters, pH45, colour brightness, and drip loss as well as morphological thyroid parameters, epithelial level, nuclear surface, and follicle diameter as well as butanol-extractable iodine in the serum. All parameters were compared with one another, and each of them was then related to net body growth and increase in high-quality pork components. Follicular epithelial level and butanol-extractable iodine were found to be in negative correlation with one another. Higher drip loss was in concomitance with relative morphological thyroid quiescence. Higher net growth was exhibited by animals with portions of high-quality pork components went along with significant deterioration of general pork quality. Six boar progenies were tested for the above parameters. Some of the boar progenies exhibited statistically secured differences with regard to the thyroid parameters, butanol-extractable iodine, and pork quality.

Abattoirs↗
PubMed1980

[Mycoplasma mastitis of cattle. 8. Pathological anatomy and histology of experimental Mycoplasma bovis mastitis].

Macroscopic and histological findings, obtained from 60 udders, are described in this paper. The animals had been infected with mycoplasma bovis and slaughtered, after something between two and 21 days had elapsed from infection. The infections and, consequently, pathologico-anatomic and histological changes were found to expand rapidly over the infected quarter and, with only little time lag, across non-infected control quarters. Roughly one week from infection, the affected quarters appeared engorged, slightly enlarged, and of tough consistence, their cutting surfaces being nodular and of moderate grey-yellowish discoloration. The same quarters were clearly reduced in size, between two and three weeks after infection, and still of tough consistence, their cutting surfaces being light brown to brown-yellow and smooth. Pronounced degeneration of alveolar epithelium, exudation of neutrophilic granulocytes, differentiated in intensity, and intra-alveolar accumulation of strongly eosin-coloured homogenous substance were the histological findings recorded between four and nine days from infection. The same alterations, yet, less strongly pronounced, continued to be recordable from now reduced alveoli, between two and three weeks from infection. Lactating tissue had entirely vanished by that time. The general pattern then was characterised by extensive alveolar atrophy and inter-alveolar infiltration of plasma cells, lymphocytes, and histiocytes. These changes proved useful in diagnosis.

Animals↗
PubMed1979

[Histometric studies of functional assessment of the parathyroid glands in healthy and sick cattle].

--Weights and mean nuclear surfaces of external epithelial bodies were examined in 53 clinically intact young fattening bulls, 49 clinically intact dairy cows, 55 young fattening bulls slaughtered on account of emergency mainly for osteolamacia and rickets, and 50 cows that had died of various diseases. --Absolute parenchymal levels were found to increase along with growing age. --In young fattening bulls, epithelial bodies lost weight and nuclear surface along with severity of pathological bone changes. --Epithelial bodies in cows and young fattening bulls feeding primarily on silage were more active than those of animals feeding to a larger extent on meadow hay or kept grazing. --No signs of increased activity of epithelial bodies were recordable from animals with osteomalacia or those close to parturition. --All results so far derived from the above studies seem to suggest that, with the present regime of cattle feeding, calcium deficit or phosphate excess are not involved in the development of skeletal diseases. The findings so far obtained in the context of epithelial bodies have confirmed the contrary to the effect that calcium excess and phosphate deficit have remained to be the major causes of skeletal diseases.

Animals↗
PubMed1979

[Histometric studies of thyroid glands of swine with treated and untreated strumata with special reference to the importance of morphological findings for the assessment of thyroid function].

Thyreocyte measurements were applied to 20 thyroids each of three groups of pigs for slaughter kept in the region of the Baltic coast. The first group consisted of clinically intact animals, the second of animals with untreated goiters, and the third of animals with goiters and potassium-iodine treatment. Hundred cells were measured in each of the animals, the magnification factor being 2,000. Mean values were calculated for each animal and group. The mean epithelial levels were 7.34 +/- 0.71 micrometer in Group 1, 13.77 +/- 1.97 micrometer in Group 2, and 4.25 +/- 0.52 micrometer in Group 3. The follicles recorded from the third group were one-a-half to three times as large as those recorded from the first. The mean thyroid weights were 11.8 +/- 5.0 g in the first group, 46.3 +/- 28.9 g in the second, and 23.5 +/- 7.9 g in the third. The relevance of such morphological findings to assessment of thyroid function is discussed. It is proposed to include such tests in any assessment of a problem situation in the context of thyroid function and in any evaluation of therapeutic success.

Animals↗
PubMed1978

[Excessive iron administration to sheep. 2. The effect on the iron, copper, zinc and manganese level in different organs].

Lambs received 250, 1000 and 1750 mg Fe per kg concentrate dry matter. The Fe-supplementations caused the Fe-levels of spleen, liver, kidneys and ribs to rise significantly. Liver and spleen reflected most markedly the high Fe-supply. The Fe-supplementation reduced the Cu-content in the liver and the share of Zn in the kidneys. The Mn-content of all body parts analysed was not significantly influenced by Fe-supplementation.

Animals↗
PubMed1978

[Pathohistological studies on so-called subclinical mastitis].

Three different localisations of each one of 118 udder quarters were histologically tested. All the 118 quarters had been clinically unchanged for not less than three months before slaughter, and the milk obtained from them had been without any major change over at least six weeks. Sixty-two quarters that had produced positive response to the highspeed mastitis test just before slaughter exhibited 45 inflammatory changes (72 per cent), most of them in terms of proliferative lobular mastitis or exudative alveolitis. One of such changes was recorded from 20 in 47 quarters (21 per cent) which had reacted negatively to the highspeed mastitis test. Comparison with the clinical history of the udders showed that 47 per cent of the established changes could be interpreted as sequels of previous clinical disorder in udder condition, while the greater part of all findings was based on completely negative udder histories.

Animals↗
PubMed1978

[Experimental study on cattle anemia due to immune antibodies. 3. Effects of anemia on the liver].

A characterisation in greater detail was undertaken of haemolytic anaemia caused by immune antibody and its effects on the liver of young cattle. Bioptate follow-up tests were applied to two animals, while bromosulphalein half-life and SGOT activity were determined in seven. Centrolobular liver necrosis was not reproducible. Some moderate liver cell damage was histologically detected. Certain responses recorded from the reticulohistiocytary part of the liver were interpreted as a consequence of aggravated damage to erythrocytes. The above moderate liver cell damage failed to produce statistically secured rises in bromosulphalein half-life nor SGOT activity.

Anemia, Hemolytic, Autoimmune↗
PubMed1976

[Ca and P metabolism in the skeletal system of the dairy cow as shown in histometric follow-up studies on the substantia spongiosa of the tuber coxae].

1. Histometric follow-up checks of the Substantia spongiosa of Tuber coxae in dairy cows have shown the trabecular percentage of the skeleton to decline continuously from the onset of lactation and to reach its lowest point in the last third of the lactation period. This was followed by some rise up to the next lactation, but the original values were not restored. 2. The percentage of spongiosa trabeculae, consequently, drops along with growing age, and so does the absolute trabecular surface. 3. No unambiguous dependence of trabecular surface on milk yield was established. 4. The results obtained from the above checks are discussed with reference to the physiological dynamics of the bone system as a mobile store of minerals. Some of the aspects mentioned are of greater relevance to practice.

Animals↗
PubMed1976

[Late lesions in cerebrocortical necrosis (CCN) of cattle].

The brains of three young fattening bulls in which cerebrocortical necrosis had been cured by intensive vitamin-B1 treatment were histologically examined six, eight, and ten months after the clinical outbreak of the disease. Shrinkage foci were detected in the cerebral cortex, their localisation and extension depending on the course of the past disease. Part of the cerebrocortical centre was void, with differentiated amounts of fatty granular cells being scattered in regions of it. The findings were taken to indicate almost complete decomposition and resorption of the liquefied necrotic tissue. Glios cicatrisation occurred in places. A vacumn that had resulted from depression of the brain surface was filled up by proliferating loose connective tissue and vessels in the leptomeningeal region. The weight increase of fattening bulls with a case history of cerebrocortical nectosis was found to be much worse than that recordable from animals with no pathological record. Continued keeping of such cured animals, therefore, seems to be of poor economy.

Animals↗