Biomedical subjects

W Sibley

Publications and source records attributed to W Sibley.

3 recordsLinked to original sources

PubMed1982

Glomus jugulare tumor.

A 53-year-old woman with left vocal cord paralysis was seen for sharp shooting pains in the left side of the neck and the left shoulder and upper arm. Glomus jugulare tumor was diagnosed, based on clinical findings and results of angiography and computed tomography. Because surgery was contraindicated, radiotherapy was used. The patient's symptoms resolved within three months, and she had had no further problems. Glomus jugulare tumor should be considered in the differential diagnosis of adult chronic otitis, deafness, tinnitus, and dysfunction of the lower cranial nerves.

Diagnosis, Differential↗

PubMed1978

Anesthesia in multiple sclerosis.

The effect of general anesthesia on 42 multiple sclerosis (MS) patients who underwent 88 episodes of general anesthesia was analyzed. One patient experienced a relapse after a procedure under general anesthesia, which is compatible with the natural history of the disease. A literature review revealed little information on this subject or on the use of particular anesthetic agents in MS. Our experience with spinal and local anesthesia is reported. In the evaluation of the former our limited data suggested that spinal anesthesia is less preferable than other alternatives in MS. Local anesthetics had a benign effect on the course of MS.

Adult↗

PubMed1977

The association of HLA antigens A3, B7, and DW2 with 330 multiple sclerosis patients in the United States.

Reported associations of HLA antigens with MS have varied considerably. In this study we have examined 330 clinically definite MS patients from the United States. The frequency of DW2 (52%) was highly statistically significant in MS patients as compared to controls (p less than 0.00001). Neither A3 nor B7 was significantly increased in MS; however, the joint occurrences of A3-DW2 (20% vs 7%, p less than 0.001) and B7-DW2 (30% vs 13%, p less than 0.0002) are highly associated with MS.

Chromosome Mapping↗