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W Skinner

Publications and source records attributed to W Skinner.

21 records · Page 2Linked to original sources
PubMedDate not supplied

Variation in antisperm antibody response following transection of male genital tract in Lewis rats.

Genital tracts of male Lewis rats were transected at various levels to determine whether this may influence antisperm antibody response. Adult male rats underwent bilateral transection of the vas deferens (group I, n = 9), mid-epididymis (group II, n = 10), and efferent duct (group III, n = 9). Group IV (n = 10) underwent a sham operation. Sera were collected by retro-orbital puncture before the operative procedure and monthly for 3 months postprocedure. Sperm-reactive immunoglobulins IgG, IgA, and IgM were measured individually as well as combined in serum by enzyme-linked immunosorbent assay (ELISA) using lithium diiodosalicylate (LIS)-solubilized washed rat caudal epididymal sperm. The maximal immune response was seen in all groups at 2 months postprocedure. Antibody response defined as the net ELISA absorbance reading for the combined immunoglobulin group were (mean +/- SEM): group I = 120 +/- 16, group II = 156 +/- 23, group III = 190 +/- 20, and group IV = 116 +/- 22. The highest antibody response was noted in the efferent duct group, which was statistically (p < .05) greater than the sham-operated and vas deferens groups. In the efferent duct group the highest immunoglobulin response was observed in the IgG class, which was significantly higher (p < .05) than the IgA and IgM classes. The transection of the male genital tract at different levels leads to variation in antisperm antibody response and that sperm located at different sites along the genital tract may differ in their autoantigenic potential.

Animals↗
PubMedDate not supplied

Big hat, no cattle: managing human resources.

When faced with business problems, managers naturally make identifying the trouble their priority. Once that is done, at least half the job is over; finding solutions is just a matter of time. This hasn't been so, however, with the human resources problem: how to motivate employees. Sixty years ago, the Hawthorne experiments revealed the issue, and ever since, managers, researchers, and consultants have been searching for the answer to the human resources problem. Why aren't employees as productive, loyal, and dedicated to their companies as their managers know they can be? The author of this article proposes four reasons why actuality has fallen so far below expectation in personnel management, namely, that managers' expectations have been too high in the first place, that the concepts staff professionals offer managers are frequently contradictory, that the corporate role of personnel has always been problematic, and finally, that managers hold assumptions concerning their employees that undermine efforts to motivate them.

Humans↗