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Biomedical subjects

W Sohn

Publications and source records attributed to W Sohn.

15 recordsLinked to original sources

[Modern pain therapy in general practice. "Pain is what the patient perceives as pain"].

Virtually one person in two is afflicted by pain. In many cases its management, in particular the chronic form, is anything but appropriate to the patient's actual needs. Adequate pain treatment begins with the acceptance of the patient's perception of pain. Pain must be differentiated not only by its cause, nature and intensity, but also by psychosocial factors (unemployment, poverty). Within the framework of a comprehensive communicative interchange between physician and patient, self-medication and explanation models offered by the patient, must be considered. An important task for the general practitioner is to appreciate the "plastic phase" of pain, in which pain memory begins to develop, so as to initiate effective analgesia early on. For this purpose, it is essential that the physician be familiar with the interfaces with specialists, as also with the WHO stepped schema, in particular the indication for powerful stage III analgesics, and with the possible need for accompanying medication.

Analgesics↗

Fluid consumption related to climate among children in the United States.

OBJECTIVE: Recommended fluoride concentrations in US public water systems are between 0.7-1.2 ppm, depending on the mean daily maximum temperature. This range assumes that water intake is higher in warmer than in cooler climates, based on research from the 1950s. The aim of this analysis is to relate fluid consumption among American children aged 1-10 years to the local climate under modern conditions. METHODS: The quantities of daily total fluid intake per body weight (ml/kg) and plain water intake per body weight (ml/kg) of children were calculated from the 24-hour recall diet survey in the third National Health and Nutrition Examination Survey (NHANES III, 1988-94). The mean daily maximum temperature from 1961 to 1990, averaged for the month during which the NHANES III exam was conducted, was obtained for each survey location from the US Local Climate Historical Database. Multiple regression analysis was conducted using SAS and SUDAAN. RESULTS: Fluid intake was significantly associated with age, sex, socioeconomic status (SES), and race and ethnicity. No significant association could be found between the amount of either total fluid or plain water intake and mean daily maximum temperature, either before and after controlling for sex, age, SES, and race or ethnicity. CONCLUSIONS: Results indicate that there is no evidence that fluid consumption among children is significantly related to mean temperature in modern conditions. This suggests that the national temperature-related guidelines for fluoride concentration in drinking water may be due for reevaluation.

Black or African American↗

The impact of universal access to dental care on disparities in caries experience in children.

BACKGROUND: The authors investigated the association between socioeconomic status and the severity of dental caries in 6- and 7-year-old children who had had access to dental care throughout their lives. The children had lived since birth in Nova Scotia, Canada, a province with a universal publicly financed dental care program. METHODS: The authors selected a representative sample of first-grade children using a stratified multistage sampling method of primary schools (n = 1,614). The response rate was 78.8 percent. Two dentists were trained to diagnose dental caries using modified World Health Organization criteria. Intra- and interexaminer reliability was excellent (kappa > or = 0.88). Of the children who were examined (n = 1,271), 955 were lifelong residents of Nova Scotia, Canada, and so were included in this analysis. Data were weighted and adjusted for clustering (design) effects. RESULTS: Only 8.4 percent of the children had visited a dental office before the age of 2 years, and 88.5 percent of the children had their first dental visit between the ages of 2 and 5 years. Children whose parents had completed a university education had a significantly lower mean number of decayed, missing and filled surfaces, or dmfs, in their primary teeth than did children whose parents had a lower education level. A Poisson regression model indicated that parents' high education status, optimal fluoride concentration in schools' water supplies, daily toothbrushing and dental visits for checkup were significantly associated with low dmfs scores. CONCLUSION: Having access to a universal publicly financed dental insurance program since birth did not eliminate the disparities in caries experience. PRACTICE IMPLICATIONS: This analysis of a highly utilized universal dental insurance program suggests that disparities in oral health status cannot be reduced solely by providing universal access to dental care. Focused efforts by professional and governmental organizations should be directed toward understanding the socioeconomic, behavioral and community determinants of oral health disparities.

Age Factors↗

Dental caries in the second millennium.

This historical review of dental caries diagnosis and management is based on information obtained from reports published between 1839 and 1965 and forty textbooks on caries diagnosis and management published since the nineteenth century. The history of understanding of any disease or condition in humans has passed through two distinct eras. The first, which lasted until the twentieth century and may still be ongoing today, is the "observational" era. The second, which has developed and revolutionized our understanding of the causes and treatments of all diseases, is the "scientific" era. During the observational era, treatments of oral or dental problems were based on neither biological nor scientific principles. Rather, experimentation without validation was, and to a lesser extent during the last fifty years is still, common. In terms of disease management, dental practice is still in the gray years of the "restorative era" and in the midst of the "preventive era" where the emphasis would soon shift towards early detection of biological markers of diseases and prevention of their initiation and progression. This review has found that most contemporary questions on caries diagnosis and management have been debated since the middle of the nineteenth century. There is a need for a comprehensive research program to provide scientifically based information to assist dental practitioners in caries detection, diagnosis, and management.

Dental Caries↗

Water consumption and nursing characteristics of infants by race and ethnicity.

OBJECTIVES: The purpose of this project was to determine racial/ethnic differences in water consumption levels and nursing habits of children younger than 2 years old. METHODS: Data from the 1994-96 Continuing Survey of Food intakes by individuals (CSFII) were used for these analyses. Water consumption and breast-feeding data on 946 children younger than 2 years old were used. RESULTS: For black non-Hispanic children younger than 2 years old (n = 121), 5.3 percent of the children were currently being breast fed. This percentage was less than that seen in other racial/ethnic groups. For white non-Hispanic children (n = 620), this percentage was 10.8 percent; for Hispanic children (n = 146), 12.2 percent; for "other" children, 18.5 percent (n = 59). Black non-Hispanic children had the highest total water consumption (128.6 ml/kg/day) among all groups, white non-Hispanic had the lowest (113.2 ml/kg/day). These differences were not statistically significant in multivariate regression modeling. Black non-Hispanic children also drank more tap water (21.3 ml/kg/day) than white non-Hispanic children (12.7 ml/kg/day) and Hispanic children (14.9 ml/kg/day). The difference was statistically significant in multivariate regression modeling. CONCLUSIONS: The differences in breast feeding and water consumption observed among black children younger than 2 years of age could be a factor in the observed higher levels of fluorosis in black children compared to other children.

Black or African American↗

Water consumption in the United States in 1994-96 and implications for water fluoridation policy.

OBJECTIVES: The purpose of this project was to describe current water consumption patterns and to compare them to findings from earlier studies. Current water consumption data also were used to reevaluate the association between water consumption and climate. These findings are of importance in estimating fluoride intake from fluoridated water. METHODS: Findings from the 1994-96 Continuing Survey of Food Intakes by Individuals (CSFII) were compared to those from two earlier dietary studies, the 1977-78 Nationwide Food Consumption Survey (NFCS) and the pioneering research of Galagan and colleagues in the 1950s. Food consumption data were analyzed for 14,619 persons with food and beverage intake data for two 24-hour periods in the CSFII. RESULTS: Increased consumption of infant formulas and decreased consumption of tap water and cow's milk were seen in the CSFII for infants compared to the NFCS. Older children and adults showed increased consumption of carbonated beverages and juices. While Galagan and colleagues found about a 60 percent increase in water consumption between the coldest (55 degrees F) and warmest (85 degrees F) conditions, only a 20 percent difference was seen between the winter and summer months in certain regions in the CSFII. CONCLUSIONS: No obvious strong or consistent association between water intake and month or season was apparent in these recent data. These findings are preliminary, and suggest that water fluoridation policy requires further research regarding water consumption and climate.

Adolescent↗

A systematic review of clinical diagnostic criteria of early childhood caries.

OBJECTIVE: This paper reviews case definitions and clinical diagnostic criteria of early childhood caries (ECC) and severe ECC (S-ECC) in children aged 1 to 5 years old. The acronym S-ECC as used in this paper refers to nursing caries, baby bottle tooth decay, rampant caries, labial caries, maxillary anterior caries, and other terms used to refer to severe dental caries in preschool children. METHODS: A search was carried out for articles published in peer-reviewed journals and indexed in MEDLINE using the following terms: nursing caries, baby bottle tooth decay, early childhood caries, rampant caries in preschool children, labial caries, maxillary anterior caries, and nursing bottle caries. MEDLINE's MeSH terms "dental caries" and "deciduous teeth" were used to search for other relevant studies. Reports were selected if they included children 1 to 5 years of age and described diagnostic criteria or case definitions of S-ECC. Three previous reviews were searched for other relevant reports. One unpublished report was included in this review and data from NHANES III were analyzed to provide information on caries patterns in preschool children in the United States. The first author read all the abstracts from the MEDLINE search and tagged relevant reports for photocopying. He also abstracted all the information from the reports. The first author calibrated the second author, who independently read all included and excluded reports. Disagreements were resolved by consensus. RESULTS: Out of 126 studies, 32 were excluded and 94 (93 published and 1 unpublished) were included in this review. Eighty-one of the 94 published studies were cross-sectional surveys or clinical studies, 7 were case-control clinical studies, 2 studies were controlled clinical trials, and 4 were cohort or field trials. About two-thirds of the included studies did not report on calibration of examiners. Information on reliability of examiners was reported by 19 of the 94 studies. The included studies varied widely in the name used to identify S-ECC, case definitions, and diagnostic criteria. "Cavitation" was the most common criterion used to define dental caries. Several studies measured early or noncavitated carious lesions. Twenty-seven studies used the presence of 1 dmf maxillary incisor to classify a child with S-ECC. Another 23 and 9 studies defined S-ECC by the presence of 2+ or 3+ dmf maxillary incisors, respectively. Dental caries in preschool children clusters in pits and fissures and on smooth tooth surfaces of primary molars and maxillary incisors. CONCLUSIONS: This review found a wide variation in the case definitions and diagnostic criteria used to diagnose ECC or define S-ECC. Dental caries in the maxillary incisors is one of several patterns of dental caries that may occur in primary teeth of preschool children. A consensus is needed on case definitions and diagnostic criteria that can assist researchers to test preventive interventions and study the etiology and epidemiology of ECC.

Bottle Feeding↗

[Benefits and risks of intramuscular injection. Are expectations of physicians and patients irrational?].

Although unsupported by scientific evidence, there is in Germany a traditional attitude of expectancy vis-a-vis the efficacy of injections which often results in this form of application being given preference over the oral route. With respect to both the indication and the observance of disinfection time and proper injection technique, adherence to existing guide lines would appear to be urgently necessary within the framework of quality assurance relating to this common form of treatment. After all, intramuscular injection continues to be high on the list of causes of treatment errors.

Attitude of Health Personnel↗

[Not Available].

Explore the source record for details and available documents.

Biology↗

[Rational therapy of chronic pain conductions by the family physician].

Despite numerous efforts to establish an adequate pain treatment, many patients still do not receive a proper pain therapy. This is unfortunate as it is estimated that between 5 and 7.6 Mi. people are suffering from chronic pain in Germany. This paper is demonstrating an adequate pain management for different diseases including an interdisciplinary approach. Further, we hope to reduce the fear of many physicians for the administration of opioid analgetics to realize a proper pain treatment where indicated.

Analgesics↗

The application of correlated sampling to the computation of electron beam dose distributions in heterogeneous phantoms using the Monte Carlo method.

Although the Monte Carlo method is capable of computing the dose distribution in heterogeneous phantoms directly, there are some advantages to computing a heterogeneity correction factor. If this approach is adopted there are savings in time using correlated sampling. This technique forces histories to have the same energy, position, direction and random number seed as incident on both the heterogeneous and homogeneous water phantom. This ensures that a history that has, by chance, travelled through only water in the heterogeneous phantom will have the same path as it would have through the homogeneous phantom, resulting in a reduced variance when a ratio of heterogeneous dose to homogeneous dose is formed. Metrics to describe the distributions of uncertainty, efficiency, and degree of correlation are defined. EGS4 Monte Carlo calculation of the dose distribution from a 20 MeV electron beam on water phantoms containing aluminum or air slab heterogeneities illustrate that this technique is the most efficient when the heterogeneity is deep within the phantom, but that improved efficiency can be realized even when the heterogeneity is at or near the surface. This is because some correlation between the two histories is retained despite passage through the heterogeneity.

Electrons↗

Characteristics of adolescents' sexual partners and their association with use of condoms and other contraceptive methods.

CONTEXT: While a number of studies have examined the association between individuals' characteristics and their contraceptive use, few studies have examined the influence of partners' characteristics on individuals' contraceptive use. METHODS: Using nationally representative data from the National Longitudinal Study of Adolescent Health, multiple logistic analyses were conducted to identify associations between the demographic characteristics of adolescents' heterosexual partners and adolescents' use of condoms or other contraceptive methods. RESULTS: The partners of white and black adolescents were likely to be similar to them, while the partners of Latino adolescents and of adolescents of "other" race or ethnicity were more likely to be of a different racial or ethnic group. Differences in age between adolescents and their partners were notable in all racial and ethnic groups. As adolescents age, the characteristics of their partners become more heterogeneous. The less similar adolescents and their partners are to one another--whether because of a difference in age, grade or school--the less likely adolescents are to use condoms and other contraceptive methods. CONCLUSIONS: Many adolescents have relationships with partners whose characteristics differ from theirs and with whom they are less likely to use condoms or other contraceptive methods. This behavior is more common as adolescents grow older. To provide appropriate counseling, sexuality educators and family planning providers need to consider the ways in which adolescents' relationships change as they age and discuss with them the dynamics of relationships involving partners who differ in age or other characteristics.

Adolescent↗