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Biomedical subjects

W Stoll

Publications and source records attributed to W Stoll.

At least 19 recordsLinked to original sources

[Adenosarcoma of the uterus].

A case of a 67-year old woman with adenosarcoma of the uterus is reported. Adenosarcoma is a mixed mesodermal tumour with a low malignant potential. It is characterised by a benign glandular and a malignant stromal component. Adenosarcomas are usually treated by hysterectomy with bilateral salpingo-oophorectomy. Patients with myometrial invasion have an increased risk of recurrence. It may be appropriate, to consider adjuvant chemotherapy or radiation treatment for these patients.

Aged

[Early premature rupture of fetal membranes and risk of lung hypoplasia in the fetus. Case report from the 22d week of pregnancy with delivery in the 30th week of pregnancy].

We report on a case of ruptured foetal membranes in the 22nd week of pregnancy. A possible risk is pulmonary hypoplasia. Although factors exist that predispose to the occurrence of pulmonary hypoplasia, the diagnosis cannot be predicted prenatally. As pulmonary hypoplasia is associated with a high neonatal mortality rate, prenatal detection would be helpful in the clinical management of early premature rupture of the membranes.

Adrenal Cortex Hormones

[Clinical relevance of malignant lateral branchial cyst].

We analyzed 7 patients with so called "maligne lateral cervical cysts" regarding the controversies in the literature. Primary tumors of oropharyngeal sites were discovered in all these cases of "branchiogenic carcinoma" rising the final diagnosis of cystic metastases. Diagnostic tonsillectomy is supposed to be important to solve this problem of differential diagnosis. The issue of malignant transformation in cysts of branchial cleft origin has to be recognized as being an oncological artifact. We argue that the "maligne lateral cervical cyst" does'nt exist as a proper entity. In analogy to the principles of the treatment of oropharyngeal cancer ipsilateral neck dissection and wide local excision of the cyst followed by radiation therapy is the suggested plan of therapeutic management. Search for a possible unknown primary tumor within the oropharynx must be continued over years.

Adult

The use of polytetrafluoroethylene for particular augmentation of the nasal dorsum.

In 24 cases scutiform polytetrafluoroethylene patches were implanted to correct saddle malformation and irregularities of the nasal dorsum. For smaller tissue defects of the nasal bone and cartilage, the patches are very suitable in rhinosurgery. One of the advantages of the implant is that it makes the reconstructed area appear as natural as possible.

Adult

[Objective assessment of disorders of visual perception following unilateral vestibular loss. Studies of the so-called Dandy symptom].

Visual ability and compensatory eye movements during defined vertical oscillation were investigated in 20 patients with unilateral lesions of labyrinthine function and in 20 normal subjects. Oscillation frequencies were performed at the rate of 1 to 1.5 Hz with an amplitude of 5 cm, comparative to head locomotions of a running person. In synchronism with this, the visual function was tested with Landolt rings. Patients complaining of subjective visual disturbance during walking and running, also presented a measurable blur of vision under test conditions. In addition, eye movements were recorded and classified into three types. However, these eye movements showed no relation to gaze function. Our results suggest that the otolith-ocular reflex may participate in adjusting the vertical eye position during vertical stimulations at low frequencies. The effect of visual disturbances in patients with labyrinthine lesions is explained by the "efference-copy" initially described by von Holst. The efference-copy is responsible for the neutralisation of provoked retinal perceptions.

Adult

[5 years experience with "open septorhinoplasty"].

Based on our experience we expected to obtain in 184 of 229 (80%) septorhinoplasties more obvious improvement with open surgery than with the closed technique. In most cases the pre- and intraoperative procedures yielded good results. The columella scar was extremely well tolerated; however, two smokers experienced a prolonged healing process with slight dehiscences. There were no severe complications. The rate of mild complications was 5.9% and consisted of infections, implant removal, and postoperative nasal obstructions. In 4% of the cases revision surgery was requested.--Summing up, external rhinoplasty is recommended for all cases with extraordinary pathology and where the correction demands excellent exposure.

Adolescent

[Indications for cesarean section].

Following introductory remarks on rates of cesarean section, the relative and absolute indications for the procedure are reviewed. The rise in the rate of cesarean sections is due to widening of the relative indications, such as dystocia, previous cesarean, fetal distress and breech presentation. Since 1974 the cesarean section rate at Aarau Gynecologic and Obstetric Clinic has fluctuated between 6% and 8% and showed an increase for the first time, to 9.3%, in 1988. Breakdown by the main indications shows fetal distress, breech presentation and history of previous cesarean. Other indications, in particular dystocia, were statistically well in the background.-The question of stabilizing and lowering the cesarean section rate is discussed. A more restrictive approach to the dystocia indication is the first priority. Precise diagnostic procedures during the labour stage, e.g. fetal blood sampling and cardiotocography, are essential. Particular attention is focused on cesarean section in relation to preterm delivery and breech presentation.

Breech Presentation

[Synchronous registration of vestibulospinal and vestibulo-ocular reflexes in rotatory stimulation].

A comparative study of vestibulo-spinal and vestibulo-ocular reactions is presented in normal subjects and in patients with different vestibular lesions. Four our investigations the rotatory chair was prepared with a special equipment for the "Vertical Drawing Test" to achieve the simultaneous recording of the nystagmus and laterotorsion reactions. Analyses of the two reflexes demonstrated a rare independence between the vestibulo-ocular and vestibulo-spinal reactions despite a common stimulus. Further studies supplying additional information laterotorsion to nystagmus, may be helpful in the analysis of balance. Variations were found in the patterns of behaviour in different groups of vestibular disturbances.

Adult

[Concave deformity of the lateral nasal cartilage. A cause of nasal stenosis].

Concave lower lateral cartilages are rare but impressive findings that can best be exposed by open rhinoplasty. Surgical treatment takes advantage of the existing vaulting of the cartilage. A 180 degrees rotation flap is recommended for unilateral cases and a cross-over rotation flap for bilateral deformities. The concave form of lateral crura is probably more frequent than suspected, and it is therefore necessary to identify this lesion and to be familiar with techniques for its correction.

Cartilage

[The gynecologic check-up].

The feelings that come with the physiological changes, bring young women the awareness for the prophylactic intention of modern medicine. An example of the check-ups is the well accepted ante-natal clinic. The most frequent reason for a young woman to make an appointment with a gynaecologist is the wish to have some sort of contraception. This consultation often means the first chance for a pap smear to be carried out. With the onset of the climacteric is for those who have neglected their earlier screening examinations, the next reason to make an appointment. At this stage the doctor will discuss the possibilities of hormonal substitutive therapy. The need of early diagnosis of cancer should be stressed with regular examination in the following years. In gynaecology the screening tests with the aim of diagnosing precancerous conditions is only possible from the cervix. This being through vaginal cytology and colposcopy. For the early diagnosis of cancer attention to the at risk groups should be observed. Associated with the cervical, endometrial, ovarian, vulvar and breast cancers are phenotypical characteristics. Special attention should be given to the taking of the pap smear. Finally the current value of a mammography will be discussed.

Adult

Decompression of the orbit and the optic nerve in different diseases.

During the past six years, visual loss in 60 patients was caused by infectious processes and mucoceles of the ethmoid region, benign paranasal tumours, endocrine ophthalmopathies, head trauma etc. Comparison of preoperative and postoperative visual function in 48 cases treated by decompression of the orbit and in 12 cases treated by decompression of the optic nerve demonstrated visual improvement of 68 percent on average. Surgically, we preferred the transethmoidal route and in some cases the lateral osteoplastic approach. With regard to the success of the surgical therapy, a correlation between the time of manifestation of the visual loss and the time of surgery was found. The results mainly depended on the underlying diseases.

Bacterial Infections

Investigations upon the mechanism of inhibition of spermatogenesis in the rat by a dimeric ethynodiol-testosterone ester.

The combination of androgens and progestogens has been shown to be a suitable male contraceptive. Previous experiments revealed that injection of a dimeric testosterone-ethynodiol ester into rats and monkeys induces azoospermia for several weeks. In order to investigate the mechanism of action, we compared the endocrine effects of a single injection of 10 mg of the dimeric ester into intact male rats with that of 6 mg of norethisterone enanthate + 6 mg of testosterone enanthate. After the injection of the dimer there was a transitory reduction of serum FSH and a strong suppression of serum LH and testosterone, of testicular testosterone and of androgen-binding protein (ABP) in the testis and epididymis for at least 8 weeks, whereas spermatogenesis was totally depressed between the 4th and 8th week. Contrary to this, the enanthates caused only a slight suppression of spermatogenesis, although serum LH, testicular testosterone and ABP were profoundly reduced. The only conspicuous difference in the endocrine pattern of both groups during the first 4 weeks was in the serum testosterone level which remained normal in the rats treated with the enanthates. The results suggest that testicular testosterone and ABP concentrations are of minor significance for an intact spermatogenesis, and that some other factors produced by Sertoli cells might be involved and possibly maintained by normal serum testosterone levels.

Androgen-Binding Protein

[Expert assessment of Menière's disease].

Ménière's disease, which is characterized by typical attacks, demands an adequate medicolegal assessment. In medical expertising the comparison with other recurrent attacks of diseases (asthma, migraine etc.) must be considered. Basing on several classifications, a diagram relating the frequency with the intensity of vertigo attacks has been compiled assessing the percentage of professional disability.

Disability Evaluation

[Hearing impairment and earache as initial symptoms of Wegener's granulomatosis].

Wegener's Granulomatosis occurs rarely. It is an autoimmune disease and as such it is a special form of panarteriitis nodosa. Manifestations are seen in various organs. Granulomatous lesions in the nose, paranasal sinuses and pharynx are very characteristic and often mark the beginning of the disease. However, a painful otitis media with combined hearing loss may also be the first sign of this generalised rheumatic disease. By describing three cases we document clinical constellations of results and summarise them in tabular form. The knowledge of these constellations prevents confusing this disease with otitis media, tuberculosis and sudden deafness.

Adolescent