Biomedical subjects

W Szostak

Publications and source records attributed to W Szostak.

12 recordsLinked to original sources

PubMed2001

[The effect of Medicago spp. on growth of Trichophyton mentagrophytes in microculture].

The study aimed at assessing effect of dried root and aerial parts of Medicago spp. on growth of Trichophryton mentagrophytes. Fungus strains were inoculated onto microcultures with Sabouraud agar supplemented each with 1 g of dried and pulverised roots or aerial parts of 3 species: Medicago arabica, M. sativa, and M. murex. The strongest inhibitory effect on T. mentagrophytes growth was that of aerial parts of M. arabica (median diameter 6 mm compared to 13 mm of control), followed by root of M. arabica (10 mm) and root of M. murex (10.5 mm)--in all cases p < 0.001. Slight inhibitory effect was also found in the case of aerial parts of M. murex (median diameter 12 mm, p = 0.03). In contrast, M. sativa has shown stimulating effect on growth of T. mentagrophytes (15 mm for root and 16.5 mm for aerial part, p<0.001).

Antifungal Agents↗

PubMed2000

Zoophilic and geophilic dermatophytoses among farmers and non-farmers in Eastern Poland.

The study was aimed at assessing the frequency of zoophilic and geophilic fungal infections among farmers compared to non-farmers in eastern Poland. The study was carried out on adult patients with a suspicion of fungal infection of skin or its appendages. Skin scrapings or nail fragments were cultured on Sabouraud agar with chloramphenicol and cycloheximide for at least 3 weeks, and then identified based on macroscopic and microscopic morphology. In total, 116 subjects were included into the farmers group, 67 females and 49 males, aged 18-88 (median 53) years. Dermatophyte infection was found in 64 farmers (55.2%). Anthropophilic dermatophytes were identified in 61 farmers (52.6%), whereas zoophilic or geophilic dermatophytes - in only 5 farmers (4.3%). Trichophyton verrucosum was found in 3 cases, while T. terrestrae and Microsporum gypseum - 1 case each. The control group comprised 74 non-farmers, 40 females and 34 males, aged 18-93 (median 47) years. Among them, dermatophyte infection was found in 35 (47.3%) patients. Anthropophilic dermatophytes were identified in 30 (40.5%), whereas zoophilic or geophilic dermatophytes in 6 persons (8.1%): M. canis in 2 patients, and T. verrucosum, T. mentagrophytes var. mentagrophytes (granulosum), M. nanum, and T. terrestrae - 1 case each. There were no significant differences between farmers and non-farmers. Zoophilic and geophilic fungi identified in our study were responsible either for superficial mycosis and/or onychomycosis, no case of deep mycoses or scalp infections were found. Our data suggest that zoophilic and geophilic dermatophytoses are not frequent among eastern-Polish farmers.

Adult↗

PubMed1991

Fat distribution and gender differences in serum lipids in men and women from four European communities.

We studied male/female differences in serum lipids in randomly selected 38-year-old men (n = 337) and women (n = 342) from various cities in The Netherlands, Sweden, Italy, and Poland. Overall, men had higher triglycerides and total cholesterol levels and lower HDL-levels compared to women (P less than 0.001). Adjustment for smoking habits, city, and body mass index did not remove the gender difference. Further adjustments for waist circumference alone and waist/hip and waist/thigh circumference ratio removed the gender differences in serum triglycerides and total cholesterol. Only adjustment for waist/thigh ratio removed the gender difference in HDL-cholesterol but linear relationships were different in men and women. The average male/female difference in serum lipids, particularly for total and LDL-cholesterol varied considerably among centers. In analyses of the data from the separate centers we found that sex differences in serum triglycerides and HDL-cholesterol in all 4 centers disappeared when adjusted for waist circumference alone and for waist/hip and waist/thigh ratio. For total and LDL-cholesterol, however, adjustment for circumference ratios tended to increase the male/female difference in 2 of the 4 centers. It is concluded that, in European men and women, fat distribution may be responsible for male/female differences in serum triglycerides but that such conclusions are less clear for HDL-, total- and LDL-cholesterol.

Adipose Tissue↗

PubMed1982