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Biomedical subjects

W Szpak

Publications and source records attributed to W Szpak.

4 recordsLinked to original sources
PubMed1990

[Evaluation of 24-hour ambulatory ECG recording in patients with mitral valve prolapse].

Among 1150 ambulatory 24-hour ecg recordings, those taken from 67 persons no more than 40 years old, suffering from paroxysmal unconsciousness or maladies suggesting paroxysmal arrhythmias, without clinical signs of ischaemic heart disease, valve defects, cardiomyopathies or myocarditis, were chosen for further analysis. Echocardiographic signs of mitral valve prolapse (MVP) were found in 33 persons (23 females), whereas in the next 34 persons (20 females) no evidence of MVP was noted. There were no statistical differences between ages, mean heart rates and incidences of the ST segment depression greater than or equal to 2 mm in these two groups. Prolongation of the QT interval greater than 440 ms was found in 8 persons with MVP and in 3 without MVP. Appearance of the single ventricular extrasystoles, sporadic or frequent, was almost identical in both groups. Whereas polymorphic extrasystoles and/or ventricular couplets were significantly more frequent in the MVP group. Our study shows that MVP is present in about a half of persons no more than 40 years old referring to Holter ecg because of symptoms suggesting arrhythmias, without other signs of heart disease; and that complex ventricular arrhythmias in these patients with MVP are significantly more frequent than in persons with similar complaints without MVP.

Adolescent↗
PubMed1990

Effect of removal of phaeochromocytoma on diurnal variability of blood pressure, heart rhythm and excretion of catecholamines.

Ambulatory 24 hour blood pressure and ECG monitoring with simultaneous estimation of the urinary excretion of noradrenaline and adrenaline were performed in seven patients with phaeochromocytoma, before and after removal of the tumour. Mean blood pressure during eight 3-hour periods, mean heart rate, and noradrenaline and adrenaline excretion during four 6-hour periods were estimated. Mean blood pressure before surgery did not show any significant circadian changes. After surgery both systolic and diastolic blood pressures were significantly lower at night than in the daytime periods. In contrast, mean heart rate before surgery was significantly lower at night than in the morning, and this relationship was greater after surgery. Ventricular arrhythmias during 24 hour monitoring were noted in three patients before and in six after surgery. These findings suggest that profound disturbances of autonomic blood pressure regulation improve after removal of phaeochromocytoma, and that ventricular arrhythmias, except for paroxysmal symptoms, tend to be less frequent before than after surgery.

Adrenal Gland Neoplasms↗