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Biomedical subjects

W T Carpenter

Publications and source records attributed to W T Carpenter.

At least 181 records · Page 10Linked to original sources
PubMed1975

Integration and sealing over. Clinically distinct recovery styles from schizophrenia.

Concepts of integration and sealing over are common clinical psychiatric parlance. Our experience studying and treating acute schizophrenic patients, primarily with psychosocial techniques, has emphasized the meaningfulness of these concepts. By studying the recovered patient's attitude toward his psychotic experiences, we have obtained material from which to formulate definitions and these concepts. Integrators tend to be curious about their symptoms, regard them as part of their life's pattern, and gain information from them, resulting in a more flexible and variable attitude toward illness than patients who seal over. The latter have rather fixed, usually negative, views of their illness, and tend not to strive to understand their psychotic symptoms nor to place their psychotic experiences in perspective with their lives before and after psychosis.

Acute Disease↗
PubMed1975

A test of the transmethylation hypothesis in acute schizophrenic patients.

Keeping biochemical determinations and clinical judgements independent, the authors investigated three aspects of the transmethylation hypothesis. They found that 26 acutely schizophrenic patients were no more likely to have bufotenine or N,N-dimethyltryptamine present in urine or elevated serum indolethylamine N-methyltransferase activity than 10 normal control subjects. The authors conclude that these are naturally occurring substances which are equally likely to be present in normal and schizophrenic subjects.

Acute Disease↗
PubMed1975

Borderline and schizophrenic patients: A comparative study.

The authors describe the evaluation and follow-up of matched samples of borderline and schizophrenic patients to determine the ways that borderline disorders are similar to or different from schizophrenia. The borderline patients presented more confusing diagnostic pictures, but they could be differentiated from the schizophrenic patients by the absence of definite or prolonged psychotic episode, by the relative severity of their dissociative experiences, by more severe anger, and by less anxiety. Despite the discrepant symptom pictures of the two patient groups, a systematic review of prehospitalization functioning and two-year posthospitalization course did not reveal significant differences between them.

Adolescent↗
PubMed1975

Platelet monoamine oxidase activity in acute schizophrenia.

The authors found normal monoamine oxidase (MAO) activity in 40 acute schizophrenic patients, in contrast to previous reports of a genetically linked platelet MAO deficit in chronic schizophrenia. Variations in MAO activity were not significantly associated with the 65 clinical variables analyzed, although there was a tendency for patients in the low-MAO group to have more severely impaired reality testing, more paranoid and grandiose delusions, better prognostic scores, and less restlessness.

Adult↗
PubMed1975

Functioning at the clinical-research interface: the clinical-research meeting.

The authors describe their experience in carrying out clinical and psychobiological research in a therapeutic milieu setting. The clinical-research meeting, composed of clinical-care staff with secondary research responsibilities, researchers, and acutely psychotic patients, proved to be a useful mechanism for identifying and resolving inevitable problems at the clinical-research interface and enhanced the effectiveness of research implementation and patient care. The authors discuss three specific areas where covert issues threatened to undermine the work of the unit-the abrogation of research responsibility, the abrogation of clinical responsibility, and intergroup competition and envy.

Acute Disease↗
PubMed1975

Integration and sealing-over as recovery styles from acute psychosis.

Integration and sealing-over are terms frequently used to describe different types of recovery from acute psychosis. Metapsychological and dynamic propositions regarding integration and sealing-over as recovery styles are presented and illustrated with clinical case material. Particular emphasis is placed on the different modes of conflict resolution characteristic of integration and sealing-over. The ego operations underlying these modes of conflict resolution are discussed.

Acute Disease↗