PubMed Health⌕ Search

Biomedical subjects

W T Clark

Publications and source records attributed to W T Clark.

At least 19 recordsLinked to original sources

Surgical repair of fracture of the os penis in a dog.

An eight-year-old male Australian cattle dog cross was presented with complete urethral obstruction secondary to fracture of the os penis which had occurred two years earlier. Obstruction was associated with callus and fibrous tissue proliferation compressing the urethra at the fracture site. The problem was satisfactorily resolved by removing excess bone and fibrous tissue and stabilising the fracture with a stainless steel finger plate.

Animals↗

Long-term survival of four dogs with disseminated Aspergillus terreus infection treated with itraconazole.

Four dogs with disseminated aspergillosis caused by Aspergillus terreus were treated with oral itraconazole for 190 to 1095 days. Infection was eliminated in 1 dog. Two dogs were treated for 1000 and 1095 days but were eventually euthanased 572 and 485 days after treatment was stopped. At necropsy both dogs had widespread aspergillosis. The fourth dog was euthanased for other reasons after 190 days of treatment when it was showing a good clinical response although there was radiographic evidence that the disease was progressing.

Animals↗

Complement C4 allotype association with and serum C4 concentration in an autoimmune disease in the dog.

Serum C4 concentrations and C4 allotypes were determined wherever possible on eight dogs with an autoimmune disorder characterized by antinuclear antibody (ANA) positivity, pyrexia, and seronegative arthritis. Three of the six dogs tested serially showed hypocomplementemia at disease onset with return to normal concentrations with clinical remission following steroid therapy. All five dogs C4 allotyped were phenotypically identical. The phenotype (C4-4) was significantly increased in the diseased dogs. Thus C4 allotype may provide a marker for susceptibility to development of an autoimmune disorder in the dog. Serum C4 concentrations may help in disease diagnosis and monitoring the effectiveness of therapy.

Animals↗

New declotting catheters for arterio-venous shunts.

Clotting is a serious problem in patients with A-V shunts. Balloon Embolectomy catheters or irrigating devices are frequently unsuccessful in declotting shunts, resulting in surgical revision of the shunt. Frequent surgical revisions reduce sites of vascular access, making it difficult to perform adequate hemodialysis. New instruments, constructed mainly of stainless steel, have been devised and used to declot A-V shunts. The instruments have been devised for specific purposes and labeled as follows: (1) Explanding Mesh, (2) Helix and (3) Rotating Cutter. These instruments will dislodge and remove organized clots, snare and cut fibrin "flaps", open and enlarge the vessel lumens. They have been used successfully in removing vascular obstructions adjacent to the vessel tips of the shunt or at the site of anastamosis of the shunt and vessel. These are the most common sites of obstruction. By prolonging shunt life we have been able to decrease the number of shunt revisions.

Arteriovenous Shunt, Surgical↗

Dynamic pulmonary compliance as a measurement of lung function in dogs.

Measurement of the dynamic pulmonary compliance was carried out on 27 normal dogs weighing 11-8 to 26-4 kg Variations in the results of repeated observations and difficulties in allowing for differences in lung size between dogs limited the usefulness of the measurement as a test of lung function. Pulmonary compliance was found to correlate better with trunk length than with bodyweight or chest circumference. The mean value for dynamic pulmonary compliance measured during inspiration in 27 normal dogs was 0-117 litre/cmH20 with a standard deviation of 0-046 litre/cmH2O. Measurements were made on six dogs with clinical respiratory disease.

Anesthesia, Intravenous↗