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Biomedical subjects

W T Hung

Publications and source records attributed to W T Hung.

At least 55 records · Page 3Linked to original sources

Extrarenal Wilms' tumor--a case report.

Extrarenal Wilms' tumor is extremely rare. To our knowledge, only 22 cases had been reported up to 1984. We treated a 5-year-old girl with an extrarenal Wilms' tumor arising in the right inguinal region. Total excision was performed. Abdominal sonogram, computed tomography (CT) scan, and intravenous pyelogram (IVP) showed normal kidneys, no other mass, and no evidence of metastasis. Postoperative chemotherapy was administered. The patient has been disease-free since first diagnosis 19 months ago.

Child↗

Primary malignant tumor of liver in infants and children in Taiwan.

During the years 1976 through 1985, 55 cases of primary malignant tumor of liver in infants and children were treated. Of the 55, 30 were histologically proved to have hepatocellular carcinoma (HCC), and ten to have hepatoblastoma (HB). HCC was diagnosed in another 14 children based on clinical findings. There was one case of liposarcoma. Distinguishing features of primary malignant tumor of the liver of children in Taiwan include: (1) a significantly greater number of HCC than HB (4.4:1); (2) a 100% (25/25) positive rate of hepatitis B surface antigen (HBsAg) with family clustering for HCC; (3) 71% of the HCC patients also suffered from liver cirrhosis; (4) male preponderance in incidence of HCC. All of these results strongly supported the idea that vertical transmission of hepatitis B virus infection from the mother plays an important role in the development of HCC in this area. A 60% resectable rate and 40% survival rate were observed in HB, but for HCC, the resectability was less than 10%. Only two children were cured of HCC. Among those without tumor resection, all, except two, children died within 1 year. No difference in survival time was observed between those who had chemotherapy and those who did not. Early diagnosis and complete excision of the tumor remains the only way to long-term survival. Monitoring of alpha-fetoprotein in high-risk children, followed by more intensive investigation for those with elevation, is mandatory for early detection of the tumor.

Adolescent↗

Congenital bile duct dilatation in children.

Fifteen children under the age of 15 were identified to have congenital dilatation of the biliary tree. Thirteen of them (87%) had dilatation of both intrahepatic and extrahepatic bile ducts, while two had extrahepatic biliary dilatation only. Visualization of both intrahepatic and extrahepatic biliary tree in small children before operation is possible by ultrasonography, endoscopic retrograde cholangio-pancreatography, or percutaneous transhepatic cholangiography. The advantage and disadvantage of those methods of examinations in children are discussed here. Dilatation of intrahepatic bile ducts is common in children with extrahepatic biliary dilatation. Assessment of both the intrahepatic and extrahepatic bile ducts bears a crucial role in the management of congenital biliary dilatation at operation and during the postoperative follow-up. Rouxen-Y hepaticojejunostomy with hepaticocutaneous arm was performed in our patients with satisfactory results. Residual intrahepatic stones could be removed through the hepaticocutaneous arm by choledochoscopy.

Adolescent↗

Experience with a modification of Duhamel-Grob-Martin operation for the treatment of Hirschsprung's disease.

Forty-two patients have been operated upon with the Duhamel-Grob-Martin operation to which has been added a partial sphincterotomy. Three patients developed anastomotic leaks and one of these died. In follow-up studies from 2 months to 9 years after operation, all patients were relieved of distension and constipation, except two, who were considered to have had an incomplete proximal resection of aganglionic bowel. There were two children with repeated attacks of enterocolitis after operation. Fecal control was good in all and, in spite of the retention of a considerable spur, there have been no problems from this. It is considered that the internal sphincter is involved in the disease and the possibility of persistent obstructive symptoms is reduced by the internal sphincterotomy which has not resulted in incontinence.

Child↗

Leakage of disposable breathing circuits.

STUDY OBJECTIVE: To determine the sites and rates of the leakage of disposable breathing circuits. DESIGN: Nonclinical, experimental study. SETTING: Experimental laboratory. INTERVENTIONS: To identify in vitro the leakage sites by bubble test and to measure the leakage rate by the increased oxygen (O2) flow needed to maintain the circuit pressure provided by an anesthesia machine previously verified to have no leaks. Breathing circuit pressures measured with a sphygmomanometer of 30, 50, 70, and 100 mmHg were studied. MEASUREMENTS AND MAIN RESULTS: Ninety-seven disposable and three reusable breathing circuits from seven manufacturers were investigated for leakage. There was a linear relationship between the circuit pressure and O2 flow at which leaks occurred. No leakage was detected in reusable circuits at 30 mmHg of circuit pressure. Leakage was found in two of the six junctions between the patient adapter and the corrugated tubing in the reusable breathing circuits at a circuit pressure of 100 mmHg. In 90% of the disposable circuits tested, the leakage rate was less than 75 ml/min at 30 mmHg of circuit pressure, but there was a wide variation in the amount of leakage among the circuits of different companies. Almost all the leakage sites were located at connections in the circuit and not in the corrugated tubing. The most common site of leakage in the disposable circuits was the junction between the patient adapter end and the corrugated tubing (57%) rather than the swivel piece (40%). CONCLUSIONS: Most disposable breathing circuits can be used safely for closed-circuit anesthesia, as the leakage volume is too small to be of clinical importance. The variation in the leakage rates stresses the importance of quality control of the connector seals.

Anesthesia, Closed-Circuit↗