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Biomedical subjects

W T Ng

Publications and source records attributed to W T Ng.

At least 55 records · Page 3Linked to original sources
PubMed2001

Treatment of childhood phimosis with a moderately potent topical steroid.

BACKGROUND: Recently, topical steroid application has been shown by a small number of studies to be an effective alternative to circumcision for the treatment of phimosis. However, only potent or very potent corticosteroids have been more thoroughly studied in this treatment option. A prospective study was conducted to determine whether comparable results could be achieved using a weaker steroid cream. METHODS: Boys, 3-13 years of age, with non-retractable foreskin due to a tight ring at the tip were offered the regimen of twice-daily preputial retraction and topical application of 0.02% triamcinolone acetonide cream. The degree of preputial retractability was assessed at presentation and at 4 and 6 weeks of treatment. Success was defined as full retraction or free retraction up to agglutination of the foreskin to the glans. RESULTS: Eighty-three boys completed the treatment. Successful retraction was achieved in 48/83 (58%) patients after 4 weeks and 70/83 (84%) patients after 6 weeks of application. The overall response rate aggregated from six published series using 0.05% betamethasone was 87% at 4 weeks and 90% on completion of treatment. Thus, the results appear inferior when analysed at 4 weeks but compare favourably with those reported for a more potent steroid on completion of the full course of treatment. CONCLUSIONS: Even though the triamcinolone cream used in the present study is less potent than the more commonly used 0.05% betamethasone valerate cream, it could effect comparable improvements in foreskin retractability after 6 weeks of treatment.

Administration, Topical↗
PubMed2001

Infantile myofibromatosis of the ovary presenting with ascites.

We report the first case of ovarian infantile myofibromatosis (IM) presenting with gross ascites in a 2-month-old girl. There was no evidence of recurrence of ascites or tumour 5 years after complete excision. IM has to be considered in the differential diagnosis of ovarian tumours in infants. Despite having the alarming histologic features of high cellularity, brisk mitotic activity, vascular invasion and necrosis, the tumour responded well to surgery alone without aggressive adjuvant therapy. The case is reported to expand the spectrum of 1) ovarian tumour pathology; 2) infantile myofibromatosis distribution; 3) causes of infantile ascites.

Ascites↗
PubMed2000

Laparascopy for definitive diagnosis and treatment of gastrointestinal bleeding of obscure origin in children.

BACKGROUND/PURPOSE: Gastrointestinal bleeding (GIB) in children with no identifiable source found after upper endoscopy and colonoscopy or GIB of obscure origin can pose a great management problem for pediatric surgeons. The recent advent of laparoscopy in children has provided a useful solution. METHODS: The authors reviewed their experience of using laparoscopy in the management of 17 children (13 boys) with GIB of obscure origin over an 8-year period. The mean age was 9.8 years (range, 3 to 17 years). RESULTS: In all patients, upper endoscopy and colonoscopy results did not show a bleeding source. Pertechnetate technetium Tc 99m scan showed positive uptake in 6 patients. Of these, 4 were found on laparoscopy to have a Meckel's diverticulum, 1 had intestinal duplication, and the remaining patient had nodular lymphoid hyperplasia at the terminal ileum. Ten patients had a negative pertechnetate scan. Of these, 3 had a Meckel's diverticulum, 1 had lymphoid hyperplasia, 1 had intestinal duplication, 1 had vascular enteritis, and 4 had normal findings on videolaparoscopy. Pertechnetate scan was not performed in 1 patient and, on laparoscopy, it turned out to be Meckel's diverticulum. Laparoscopic-assisted small bowel resection was performed successfully in all patients with Meckel's diverticulum, intestinal duplication, and nodular hyperplasia. Conversion to open surgery was required in the patient with extensive ileal vascular enteritis secondary to Henoech Scholein purpura. All patients, including the 4 with normal findings on laparoscopy, had made uneventful recovery without further episode of bleeding. CONCLUSION: Laparoscopy is a useful diagnostic as well as therapeutic tool in children with GIB of obscure origin.

Adolescent↗