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Biomedical subjects

W Tanghe

Publications and source records attributed to W Tanghe.

At least 19 recordsLinked to original sources

Value of axillary ultrasonography and sonographically guided puncture of axillary nodes: a prospective study in 144 consecutive patients.

The value of axillary sonography in 144 consecutive patients was prospectively studied. Abnormal lymph nodes were demonstrated in 72 axillae, only half (36 of 72) of which were clinically detected. In comparison with intraoperative findings in 47 patients with breast carcinoma, the sensitivity of sonography in detecting malignant nodes was 92%, the specificity 95%, and the positive and negative predictive value 96% and 91%, respectively. In 42 patients a sonographically guided node puncture was performed. Evidence of malignancy was found in 38 (90.5%). In 14 (33%) of them, cyto-histology pointed to a clinically undetected primary malignancy.

Adult↗

[Squamous esophageal papillomas].

In three patients, two women of 37 and 58 and a man of 68 years, a papillomatous lesion was incidentally detected in the distal part of the oesophagus. Microscopically a squamous papilloma was seen with parakeratosis and in two patients poikilocytosis, indicating an infection with human papilloma virus (HPV). The lesions were removed endoscopically, in one patient with laser photocoagulation. Squamous papillomas of the oesophagus are benign tumours with a very low incidence. The pathogenesis still remains unclear. Some authors suggest local irritation as a possible mechanism. On the other hand there is growing evidence of an aetiological role of HPV. In several studies the presence of viral antigen or DNA has been demonstrated. These papillomas may undergo malignant transformation, which means that they are best removed preventively.

Adult↗

Chondrosarcoma of the skull base: CT, MR and pathological features.

We report on CT and MR image findings of a skull base chondrosarcoma. Chondroid mineralisation, a histological feature of chondrosarcoma, can be recognised on CT and is, together with the off-midline position of the tumour, the most characteristic finding. Differentiation is usually made by histological and immunocytochemical staining. Surgery, proton radiation therapy and stereotactic single high-dose irradiation have been used to treat patients with chondrosarcoma. It is worth mentioning that it was likely that the chondrosarcoma in our patient represented a malignant degeneration of an enchondroma that had been resected 30 years earlier.

Aged↗

Case report 814: Fibrolipoma of the median nerve.

A case of fibrolipoma of the median nerve was described. Peripheral nerve tumors of the upper extremity are very rare. Within this group of tumors, the fibrolipoma is an exceedingly uncommon entity. It was first described in 1953, and to date less than 100 cases have been described. The purpose of this report was to point out a characteristic sign of fibrolipoma, which in our opinion allows distinction on CT and MRI between fibrolipoma and the other peripheral nerve and fatty soft tissue tumors.

Child↗

Ischemic colitis in a patient with Crohn's disease taking an oral contraceptive and an ergotamine alkaloid.

A 22-year-old woman developed transient left-sided ischemic colitis with submucosal oedema and bleeding, six weeks after an uneventful right hemicolectomy for Crohn's disease. The thrombogenic properties of the contraceptive pill and the concomitant use of an ergotamine alkaloid were thought to be the cause of this complication in a patient at risk. An increase of procoagulant activity and underlying vascular injury has been described in Crohn's disease.

Adult↗

[Otologic manifestations of Wegener's disease].

Two cases of otologic involvement in Wegener's granulomatosis are reported. Symptoms are referable to those of an acute otitis media with impaired hearing. The ANCA test is helpful in the diagnosis. Immunosuppressive therapy in association with corticosteroids is the treatment of choice.

Adrenal Cortex Hormones↗

Eosinophilic granuloma of bladder.

Eosinophilic granuloma of the bladder, a rare and certainly poorly known disease, simulates bladder neoplasms. Clinical aspects, histology, and therapy in a young boy are described.

Adolescent↗

Fibrous mesothelioma. Case report.

A case of fibrous mesothelioma is presented. Chest films suggested an elevation of the left diaphragm and a limited pleural effusion, which was confirmed on computed tomography. Percutaneous needle biopsy showed mesothelial cells. At thoracotomy the tumor was attached to the pleura of the mediastinum by a pedicle. Complete surgical resection was possible. Clinical, radiological and histological data in literature are summarized. The radiological features of the presented case correspond to those described in the literature.

Female↗

[Sialadenoma papilliferum].

In this article we described a case of sialadenoma papilliferum detected in an old lady during a complete clinical survey for unrelated causes. This tumor did not produce any symptoms. The sialadenoma papilliferum was first described as a separate entity in 1969. Since several other reports have been made but the tumor is definitely rare, usually an accidental finding and most commonly localized in the mouth in the transition zone of soft and hard palate. Our case is the first published in a woman and as yet also the oldest. A survey of the literature is given.

Aged↗

Partial trisomy 14q due to familial t(14q-,11q+) translocation.

A malformed male newborn with partial trisomy for the distal part of the long arm chromosome 14 (14q23 leads to 14 qter) is described. This anomaly arose as a segregation product of a balanced t(14q-,11q+), translocation in the father.

Abnormalities, Multiple↗