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Biomedical subjects

W Thilo

Publications and source records attributed to W Thilo.

At least 37 records · Page 2Linked to original sources

[Immunity reaction in old age (author's transl)].

It was found that 61 per cent of ageing persons (average age 73 years) had no protective concentrations of tetanus antitoxin in their serums. After active immunization with a vaccine (tetanus toxoid) the increase of the tetanus antitoxin concentration was slower and lower in old age compared to the young age.

Adolescent↗

[Demonstration of the anti-thrombocyte effect of anti-human lymphocyte serum].

A report is given how the antithrombocytic effect of 13 charges of human anti-lymphocyte globulin from the horse can be identified. The investigations were performed in mice and with the thrombocyte agglutination test. The test findings in mice correspond with those of the human compatibility control. Therefore, the test in mice is recommended to be used for the laboratory examination of anti-human lymphocyte globulins.

Agglutination Tests↗

Pertussis vaccine: reactivity in animal and man.

Clinical investigation of the reactivity of diphtheria-tetanus-pertussis (DTP) vaccines is a routine control in the GDR. This paper shows the results of the clinical control of 26 batches of DTP vaccine in comparison with animal tests (weight-gain-test, histamine-sensitizing test, dermonecrotic test). The animal tests gave no support to innocuity. The batches were tested on 427 children and passed the requirements for reactivity. After a storage for 2 years the control of 3 different batches was repeated. Two of them showed side reactions in children in spite of the fact that the results of the weight-gain test did not change.

Animals↗