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Biomedical subjects

W V Delaney

Publications and source records attributed to W V Delaney.

At least 19 recordsLinked to original sources

Photocoagulation using the Eisner cone.

Thirteen patients with clinical or subclinical retinal detachments were treated with photocoagulation with the aid of a device for scleral depression and the three mirror contact lens. The Eisner cone has proven helpful in achieving clinically white retinal burns at the margins of retinal breaks by displacing subretinal fluid at the time of treatment. Patients selected for treatment had adequate pigmentation for a good photocoagulation response, nearly clear ocular media, and minimal vitreo retinal traction. Extent of retinal detachment was not a determinant, but minimal retinal elevation at break locations proved beneficial. No immediate flattening or adhesion of the retina was seen on release of scleral depression at the time of photocoagulation. White clinical burns remained visible. In 12 of 13 patients the retina was in apposition to the retinal pigment epithelium around the breaks at the first post-treatment examination. The remaining subretinal fluid absorbed in even the most extensive detachment in 2 weeks. One patient with multiple breaks at the equator failed to respond to this technique and required a scleral buckle.

Aged

Hemorrhagic peripheral pigment epithelial disease.

Hemorrhage under the retinal pigment epithelium and neurosensory retina occurred in the temporal periphery of ten patients with aging macular degeneration and one patient with histoplasmosis syndrome. The macula was not the source of bleeding. Peripheral subretinal neovascularization, commonly seen histopathologically, may be the cause. The visual recovery was poor, and most patients failed to regain lost vision once peripheral hemorrhage occurred. The differential diagnosis includes retinal detachment, uveal effusion, hemorrhagic retinoschisis, choroidal melanoma, and metastatic tumor.

Aged

Partial evulsion of the optic nerve.

A 12-year-old boy had partial evulsion of his optic nerve caused by blunt trauma and maintained good vision. Elevation of the macula, resulting probably from a leak of cerebrospinal fluid under the neurosensory retina from the disc margin, resolved spontaneously in two weeks.

Child

Analysis of monochromatic green argon-laser treatment for age-related macular degeneration.

A retrospective evaluation of 61 consecutive age-related disciform macular degeneration patients who received green argon-laser photocoagulation was done to evaluate the visual results and to search for characteristics of the presenting lesion that correlated with prognosis. For subretinal new vessels within 200 micron of the foveal avascular center, average pretreatment visual acuity was 20/80 and post-treatment 20/200. Twenty-eight percent improved, 36% stabilized, and 36% had worse acuity at last follow-up. Where new vessels were more than 200 micron from the foveal center, 36% improved, 20% stabilized, and 44% had worse acuity. The average pre- and post-treatment visual acuity for this group was 20/80. Overall, 36% required more than one treatment, and associated retinal vascular obliteration was noted in 31%. Hemorrhage over part of the neovascularization, turbid pigment epithelial detachment, and pigment epithelial detachment in the foveal avascular zone were signs that yielded the worst visual prognosis.

Aged

Retinal detachment in the second eye.

Bilateral retinal detachment (RD) occurred in 13% of 737 patients, with an interval between detachments of up to 30 years. Bilateral RD was more common in male patients and in those having more than 3 diopters of myopia. Detachment in the second eye was caused by retinal breaks in previously observed degeneration in 43% and in unsuspected diseased retina 57%. A significant number of patients with bilateral RD had multiple breaks. Aphakic RD occurred in bilateral RD and in unilateral RD patients at a comparable frequency; 28% of bilateral (mean duration, four years) and 35% of unilateral aphakic RDs occurred within one year of cataract surgery. Symptoms from retinal breaks were not reliable prognostic factors; only 39% of patients had warning before RD. Patients with bilateral RD had more reoperations with fewer successes, factors suggesting greater severity than unilateral RD.

Adolescent

Numerical grading of the disc.

The current method of grading the optic disc cannot replace stereoscopic photography. The present method of describing the optic disc is misleading and does not supply as much information as could be provided. The proposed method adds both vertical and horizontal dimensions. It takes very little time to record and supplies both the reader and subsequent examiner with a more detailed description of the disc, cup, disc ratio.

Glaucoma

Occlusive retinal vascular disease and deafness.

An 8-year-old white girl with a history of vertigo, nausea, and vomiting developed a progressive hearing loss, bilateral retinal arteriolar narrowing in each eye, vasoproliferation, and subsequent intravitreal hemorrhage. An attempt at peripheral retinal ablation with cryotherapy in the left eye resulted in retinal detachment. Spontaneous retinal detachment occurred in the right eye and was successfully repaired. Repeated intermittent hemorrhages occurred despite intraocular diathermy. Three years after onset, visual acuity was R.E.: 6/21 (20/66) and L.E.: light perception. She remains totally deaf. A 20-year-old white woman developed severe bilateral sensorineural hearing loss with poorly functioning labyrinths, followed by midperipheral retinal arteriolar occlusions and vasoproliferation on the optic nerve head. Progressive retinal neovascularization was followed by rubeosis iridis and repeated episodes of intravitreal bleeding. Six years after onset, visula acuity was R.E.: hand motions, and L.E.: 6/3 (20/100). She remains totally deaf. Both patients were of normal gestation, development, and mentality, without evidence of other systemic disease. The cause of this disease was not found.

Adult

Equatorial lens pigmentation, myopia, and retinal detachment.

Five myopic male retinal detachment patients had pigmentation of the lens equator that mildly obscured the view of the ora serrata. It may be related to a prepigmentary glaucoma state or to development of the ciliary ring predisposing to retinal detachment, or both.

Adult