Biomedical subjects
W V Howard
Publications and source records attributed to W V Howard.
Sedation and cerebral angiography. The effects of pentazocine and midazolam on arterial carbon dioxide tension.
A study of the effects of sedation on arterial blood gases in patients undergoing cerebral angiography was performed. Twenty-one patients received pentazocine (30 mg) and midazolam (5-22.5 mg) and arterial carbon dioxide and oxygen tensions were measured from radial artery samples before and during the procedure. A statistically significant rise in arterial carbon dioxide tension was demonstrated. It is suggested that this may cause a rise in intracranial pressure by increasing cerebral blood flow in a group of patients in whom there is a high incidence of raised intracranial pressure. The clinical significance of this increase in arterial carbon dioxide tension is discussed.
Postoperative vomiting.
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