PubMed Health⌕ Search

Biomedical subjects

W V Sharp

Publications and source records attributed to W V Sharp.

6 recordsLinked to original sources
PubMed1992

Initial experience with laparoscopic surgery: establishing a new surgical procedure.

Laparoscopic surgery impacted the surgical world in the United States in 1990. This report reviews the initial experience of 34 surgeons in 8 teaching hospitals of the Northeastern Ohio Universities College of Medicine. There were 538 cases reported from May 1, 1990 to January 31, 1991. There was no mortality and the morbidity rate was 4.8%, including three bile duct injuries. The conversion rate to an open procedure was 6.1%. The criteria for credentialing, training, and resident and faculty education are included. The data reported by the Surgery Department of Northeastern Ohio Universities College of Medicine are very similar to reported series from the current literature.

Adult↗
PubMed1979

Thrombogenic potential of dacron grafts after prior exposure to whole blood, plasma, or albumin.

On hundred forty six (146) vascular graft insertions have been examined to determine the best exposure media, the mode of exposure, and the time of exposure required to change the TP of knitted dacron fabric. Whole blood, plasma, albumin, and Ringer's lactate (as control) were the media used. The mode of exposure was by either simple soaking or physiological perfusion with the appropriate media. The time of exposure was from one hour to 7 days. Simple soaking in species-specific albumin was found to be highly effective in lowering the TP of knitted dacron and we advocate this as the initial step in preclotting dacron grafts. This step is equally critical in the smaller vascular replacements and should lead to improved patency of these dacron vascular grafts.

Animals↗
PubMed1978

Thromboresistance of pyrolytic carbon grafts.

This study reports in vivo testing of ULTI carbon coated dacron grafts in the dog's 4 mm carotid artery, and showed 97.5% patency at 21 days in 40 grafts compared to 33% in 6 control grafts. Physical properties of the dacron substrates were not altered after ULTI carbon deposition. The carbon coated grafts must be carefully cleaned and maintained in that condition. This initial study with the modified pyrolytic carbon adds a new dimension to vascular prosthetics and artificial organ development.

Animals↗
PubMed1978

Pyrolytic carbon-coated Dacron grafts.

A new pyrolytic carbon surface (ULTI) was tested on a loosely knitted dacron substrate in dogs. Patency was 97.5% as compared with a control of 33%. Physical properties of the dacron were not altered by the ULTI carbon deposition process. This modified pyrolytic carbon on a dacron substrate is a very promising vascular biomaterial for small vessel replacement.

Animals↗
PubMed1976

Endothelial-cell development: pressure-flow phenomena.

Scanning electron micrographs showed directional orientation and cytoplasmic changes in the seeded cells after 21 days of perfusion. From this evidence it is theorized that human fibroblasts, exposed to physiological pressures and flows, exhibit morphological characteristics similar to arterial endothelial cells. Conceivably, cells other than fibroblasts (i.e., multipotential cells) would show the same response to these pressure and flow conditions.

Blood Circulation↗