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Biomedical subjects

W V Stoecker

Publications and source records attributed to W V Stoecker.

9 recordsLinked to original sources

Border detection on digitized skin tumor images.

A radial search technique is presented for detecting skin tumor borders in clinical dermatology images. First, it includes two rounds of radial search based on the same tumor center. The first-round search is independent, and the second-round search is knowledge-based tracking. Then a rescan with a new center is used to solve the blind-spot problem. The algorithm is tested on model images with excellent performance, and on 300 real clinical images with a satisfactory result.

Humans↗

Neural network diagnosis of malignant melanoma from color images.

Malignant melanoma is the deadliest form of all skin cancers. Approximately 32,000 new cases of malignant melanoma were diagnosed in 1991 in the United States, with approximately 80% of patients expected to survive five years [1]. Fortunately, if detected early, even malignant melanoma may be treated successfully. Thus, in recent years, there has been rising interest in the automated detection and diagnosis of skin cancer, particularly malignant melanoma [2]. In this paper, we present a novel neural network approach for the automated separation of melanoma from three benign categories of tumors which exhibit melanoma-like characteristics. Our approach uses discriminant features, based on tumor shape and relative tumor color, that are supplied to an artificial neural network for classification of tumor images as malignant or benign. With this approach, for reasonably balanced training/testing sets, we are able to obtain above 80% correct classification of the malignant and benign tumors on real skin tumor images.

Adolescent↗

Computer-aided diagnosis of dermatologic disorders.

In conclusion, several computer programs have been developed to aid diagnosis in dermatology. These have used various methods to reach a diagnosis, with some earlier programs using probabilistic techniques and later programs using cognitive models. Several current trends, if they continue, would indicate that computer-assisted diagnosis may play a greater role. The growing number of physicians who own the prerequisite computing resources will probably want diagnostic software to accompany their office management and data base software. The increasing ease of use of diagnostic software, with rapid access and ease of updating, should make these programs more attractive to physicians. Some of the newer peripheral devices such as optical disks and voice input will probably make the software more interesting. Perhaps the most important factor governing the acceptance of computer diagnostic adjuncts is whether the software will provide a useful service to physicians. If these programs can be demonstrated to improve patient care, they may become commonplace in physicians' offices.

Artificial Intelligence↗

Skin cancer recognition by computer vision.

Automatic detection of several features characteristic of basal cell epitheliomas is described. The features selected for this feasibility study are semitranslucency, telangiectasia, ulcer, crust, and tumor border. Image processing methods used in this study include frequency analysis of the Fourier transform of the image, the Sun-Wee texture analysis algorithm, and several other image analysis techniques suitable for skin photographs. This image analysis software is designed for use with AI/DERM, an expert system that models diagnosis of skin tumors by dermatologists.

Basal Cell Carcinoma↗

Digital imaging in dermatology.

In this article we discuss the recent surge in activity in digital imaging in dermatology. The key role of digital imaging as an adjunct to detection of early malignant melanoma, with application in following patients with the dysplastic nevus syndrome, is explored. Other current and future uses of digital imaging in image archiving, in clinical studies such as hair growth studies, and in telediagnosis are reviewed. We review the varying research activities of image analysis laboratories participating in the dermatology image researching group. Research laboratories included in this group are at Oregon Health Sciences University, Xerox Corporation, University of Arizona, University of Cincinnati, University of Munich, University of Wurzburg, University of Arkansas, Harvard University, Southern Illinois University-Edwardsville, Johns Hopkins University, National Institutes of Health, and University of Missouri at Columbia and Rolla. The role of new imaging devices in dermatology including the "nevoscope" and the dermatoscope is explored. Goals and challenges for the new technology are discussed.

Dermatology↗

Texture in skin images: comparison of three methods to determine smoothness.

Smooth texture, a critical feature in skin tumor diagnosis, is analyzed using three texture measurement methods. A dermatologist classified 1290 small blocks within 42 tumor images as smooth, partially smooth, or nonsmooth. Texture discriminatory power of three methods were compared: the neighboring gray-level dependence matrix (NGLDM) method of Sun and Wee, the circular symmetric autoregressive random field model of Kashyap and Khotanzad, and a new peak-variance method. The texture analysis method that allows best prediction of smoothness for our tumor domain is the NGLDM method, affording 98% correct prediction of a smooth block with 21% false positives. We discuss applicability of texture analysis to dermatology.

Algorithms↗

Automatic detection of asymmetry in skin tumors.

Asymmetry, a critical feature in the diagnosis of malignant melanoma, is analyzed using a new algorithm to find a major axis of asymmetry and calculate the degree of asymmetry of the tumor outline. The algorithm provides a new objective definition of asymmetry. A dermatologist classified 86 tumors as symmetric or asymmetric. Borders of tumors were found either manually or automatically using a radial search method. With either method, asymmetry determination by the asymmetry algorithm agreed with the dermatologist's determination of asymmetry in about 93% of cases.

Algorithms↗

Automatic detection of irregular borders in melanoma and other skin tumors.

An irregularity index previously developed is applied to detect irregular borders automatically in skin tumor images, particularly malignant melanoma. The irregularity index is used to classify various tumor borders as irregular or regular. This procedure processes tumor images with borders automatically determined by a radial search algorithm previously described. Potential use of this algorithm in an in vivo skin cancer detection system and errors expected in the use of the algorithm are discussed.

Algorithms↗

An automatic color segmentation algorithm with application to identification of skin tumor borders.

A principal components transform algorithm for automatic color segmentation of images is described. This color segmentation algorithm was used to find tumor borders in six different color spaces including the original red, green, and blue (RGB) color space of the digitized image, the intensity/hue/saturation (IHS) transform, the spherical transform, chromaticity coordinates, the CIE transform and the uniform color transform designated CIE-LUV. Five hundred skin tumor images were separated into a training set and a test set for comparison of the different color spaces. Automatic induction was applied to dynamically determine the number of colors for segmentation. Ninety-one percent of image variance was contained in the image component along the principal axis (also containing the most image information). When compared to a luminance radial search method, the principal components color segmentation border method performed equally well by one measure and 10% better by another measure, including more near border points outside the tumor. The spherical transform provides the highest success rate and the chromaticity transform the lowest error rate, although large variances in the data preclude definitive statistical comparisons.

Algorithms↗