Biomedical subjects
Publications and source records attributed to W Van de Sompel.
The ocular ischemic syndrome is characterised by ocular symptoms and signs secondary to severe carotid artery obstruction. In this paper, two cases of bilateral ocular involvement are presented. The first case was caused by severe bilateral carotid stenosis and the second by bilateral occlusion of the carotid artery.
Multifocal choroiditis and punctate inner choroidopathy cause scattered acute chorioretinal lesions in the fundus. Secondary choroidal neovascularization and, more rarely, diffuse subretinal fibrosis without obvious neovascularization are associated with both syndromes and cause severe visual loss. Both disorders are of unknown etiology and have many similarities. It is our purpose to present four such cases with emphasis on their fluorescein and indocyanine green angiographic appearance. We review shortly the literature on the subject.
Acute macular neuroretinopathy is a rare disease that has been described mainly in women taking hormonal contraceptives. An association either with a viral illness or with the parenteral use of sympathomimetics was sometimes found. We describe its occurrence in a 22-year-old female following an anaphylactic shock after a bee sting, and in a 26-year-old female following a pregnancy complicated with vena cava syndrome and delivery by caesarean section. A combination of factors including hypoperfusion, Valsalva stress, estrogen-induced hematological and rheological changes, and alpha-adrenergic stimulation apparently provoked this clinical manifestation.
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