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Biomedical subjects

W W Deng

Publications and source records attributed to W W Deng.

13 recordsLinked to original sources

[The role of pentoxifylline in acute lung injury complicated by pancreatitis].

Caerulein-induced acute pancreatitis in rats commonly complicated ARDS-like acute lung injury. Acute pancreatitis induced by caerulein in the circulating neutrophil-depleted rat by hydroxyrea or with the administration of SOD, CAT or Pentoxifylline, the wet lung weight, lung capillary endothelial permeability decrease significantly compared to the caerulein group (P < 0.05). There are no lung morphologic evidences of neutrophil sequestration, interstial edema, intralveolar hemorrhage that seen in caerulein infusion animals. But it has no effect against the development of acute pancreatitis. It suggested that neutrophil and neutrophil-derived oxygen radical are the important mediators of acute lung injury complicated by pancreatitis.

Animals↗

[Lung biopsies with light microscopic and ultrastructural observations in 34 cases of diffuse pulmonary diseases].

Lung biopsies with light microscopic and ultrastructural observations were performed in 34 cases of diffuse pulmonary diseases. Open lung biopsy 2 cases, transfiberoptic bronchoscopy lung biopsy 32 cases. There were 19 (56%) idiopathic interstitial fibrosis, 3 (9%) pulmonary alveolar proteinosis, 3 (9%) pulmonary sarcoidosis, 1 (3%) idiopathic pulmonary hemosiderosis, 2 (6%) pulmonary mycosis, 1 (3%) alveolar cell carcinoma, 2 (6%) pulmonary tuberculosis and 3 (9%) pulmonary collagen diseases. Diagnosis was based on clinical data and pathologic manifestation. Lung biopsy with light and electronic microscopic examination is useful in etiologic diagnosis and differential diagnosis for diffuse pulmonary diseases.

Adolescent↗

[Analysis of multiple stepwise regression for prognosis in patients with bacterial pneumonias in elderly].

This paper was based on the material of 100 patients with elderly bacterial pneumonias, doing analysis of multiple stepwise regression for factors effecting prognosis with IBC-PC electronic computer. 100 patients (82 men, 18 women), average ages were 69.6 +/- 7.9 (60-90) years. According to the materials of clinical selected 39 items of possible affect prognosis factors. Item is independent variable (xi). The prognosis is emergency variable (y). Between both were doing analysis of regression, factors of significance were selected to multiple regression equation. In order to decide the closer relations degree between the xi and the y the F values were regulated. Using quantitative analysis and measure, the primary factors were founded. When F value is equal to 1, selected 22 factors related to prognosis. F value is equal to 2, selected factors decrease to 12, F value is equal to 3, selected factors were 6 items. Respectively, F value is 4, 5, selected factors were 5 items, they have very close regression coefficient. That showed the equation was tendency stable. According to the big or small standard regression coefficient, the sequence of affecting prognosis factors were course of disease, upper digestive tract haemorrhage, dielectric disorder, respiratory failure and gram-negative bacilli infection. The result of analysis showed that the key factors were: treatment and diagnosis without delay, pay great attention to examine of pathogen and management of complication.

Aged↗