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Biomedical subjects

W W Ebong

Publications and source records attributed to W W Ebong.

At least 19 recordsLinked to original sources
PubMed1987

Septic arthritis in patients with sickle-cell disease.

The presenting features, modes of treatment and sequelae of septic arthritis of 50 joints in 31 Nigerians with sickle-cell disease were studied prospectively over a 66-month period. Most patients were in the second or first decade of life. Males predominated, and the hip was the commonest site of involvement. Infection was polyarticular in 39% and was associated with osteomyelitis in 84%. Most presented with a long history of local disease. The remainder were toxic and desperately ill patients in whom arthritis occurred later. Gram-negative infection predominated, and the commonest organism was Salmonella. Treatment was conservative in most cases, and arthrotomy was performed in only 12 joints. No deaths resulted, but severe complications occurred in 76%, apparently due to delay in diagnosis, severity of illness and a high incidence of hip-joint infection.

Adolescent↗
PubMed1986

Aseptic necrosis of the femoral head in sickle-cell disease.

Aseptic necrosis of the femoral head accounted for 75 (28.2%) of the 266 major skeletal complications seen in 207 patients with sickle-cell disease in a 66-month period. Forty-five (60%) of the 75 patients were males. The onset of symptoms occurred between the ages of 10 and 29 years in 60 (80.0%) of the patients, and the mean age at onset was 20.8 (range 8-54) years. There were 37 patients with sickle-cell anaemia (SS) with 46 hips affected by necrosis, and 38 patients with sickle-cell haemoglobin C with 40 affected hips. Perthes-like changes occurred in 40 hips, osteochondritis dissecans-like lesion in one hip and severe hip deformity in 45 hips. Four of the five hips with Perthes-like necrosis which were treated by rotation upper femoral osteotomy had partial reconstitution of the femoral head, and all five were symptom-free. The other hips were treated conservatively with generally poor results.

Adolescent↗
PubMed1986

Acute osteomyelitis in Nigerians with sickle cell disease.

Acute osteomyelitis comprised 78 (29.3%) of the 266 major skeletal complications seen in 207 patients with sickle cell disease in a five and a half year period. Forty eight (61.5%) of the 78 patients were under the age of 15 years, and the mean age at onset was 12 years (range 9 months to 50 years). Osteomyelitis was often multifocal (in 42% of the cases) and associated with some life threatening disorders. Salmonella accounted for 50% of the 36 organisms isolated from 32 patients with bacteriologically confirmed diagnosis. The 'best guess' antibiotic was a combination of chloramphenicol and cloxacillin. Medical treatment alone proved adequate in most cases. No deaths resulted, but 55% of the patients developed serious complications due partly to the severity of the disease and also to infection involving the epiphyses and joints.

Acute Disease↗
PubMed1985

Osteoarthritis of the knee in Nigerians.

Eighty-one patients with 116 osteoarthritic knees were seen by the author at the University College Hospital (UCH), Ibadan in six years. Below the age of 50 the disease was significantly commoner among Nigerians than Caucasians; 39.5% of our patients were less than 50 years old, compared with 1.1% of Caucasians. In contrast with the latter group, trauma was apparently an insignificant predisposing factor of knee degeneration in our patients. In some cases osteoarthritis was associated with severe valgus deformity in rather young patients, suggesting a probable causal relationship. Multiple joint osteoarthritis was significantly less common in Nigerians than in Caucasians.

Adult↗
PubMed1983

Sinography in chronic fistulating osteomyelitis in sickle-cell anaemia.

The sinographic appearances in 18 long bones of 14 consecutive patients with sickle-cell anaemia and chronic haematogenous osteomyelitis were studied prospectively; the observed features were compared with the plain radiographic and operative findings. Four sinographic patterns were noted: (1) infected bone cavities with or without sequestra; (2) extensive soft-tissue tracks, alone or in association with infected bone cavities; (3) narrow, wavy intramedullary tracks; (4) short sinus tracks in the soft tissue. Plain films were of no value in demonstrating the presence and extent of soft-tissue and narrow intramedullary tracks; they failed to show infected bone cavities in four instances because of very sclerotic bone. The sinographic features correlated well with the operative findings and contributed significantly to the choice of definitive treatment in 13 out of the 18 bones.

Adolescent↗
PubMed1980

The treatment of severely ill patients with sickle cell anemia and associated septic arthritis.

The clinical features, pathogenesis, and results of conservative treatment of septic arthritis in 8 patients with sickle cell anemia (HbS) and one patient with HbS + C followed for an average of 2.8 years have been reviewed. All but one of the patients were children under 14 years of age. Hematogenous, symmetrical polyarticular arthritis predominated. The hip and the ankle were the joints most often affected. Clinically, the patients fell into 2 groups, namely, those with little or no systemic disturbance, in whom infection was localized to affected joints mainly; and critically ill patients in whom arthritis occurred later during the course of the illness. Gram-negative infection was dominant, and Salmonella was the most common organism cultured. There were no deaths, but the morbidity and complications were quite high. The sensitivity pattern of the bacteria isolated from this small series of patients suggests that a combination of gentamycin and cloxacillin possibly is the antibiotic combination of choice for the critically sick child with HbS complicated by polyarticular septic arthritis in West Africa, provided the child's renal function is adequate.

Adolescent↗
PubMed1978

The pattern of fractures and dislocations in western Nigeria.

A consecutive series of 2579 patients with 2571 fractures and 189 dislocations was studied prospectively. Males and children, especially under 10 years of age, predominated. The majority of the injuries resulted from falls either in the home or outdoors and from road traffic accidents. Fractures occurred more commonly in the upper limb than in the lower limb or the axial skeleton. Fractures of the shaft of the femur were three times more common, while fractures of the neck of the femur were less common by the same factor, in Africans than in Caucasians. Dislocations were commonest at the shoulder and elbow. Only 11.4 per cent of the patients had open operations. The prognosis as regards survival and functional results was very good, but malunion was the most common complication.

Adolescent↗
PubMed1978

False aneurysm of the profunda femoris artery following internal fixation of an intertrochanteric femoral fracture.

A case is presented of traumatic aneurysm of the profunda femoris artery following spontaneous unscrewing of the nut at the nail--plate junction of a two-piece nail plate which was used for internal fixation of an intertrochanteric femoral fracture. Methods of avoiding this complication during hip operations are described, together with a short review of the literature.

Aneurysm↗
PubMed1978

Pattern of bone injury in Ibadan.

A series of 1,329 patients with 1,327 fractures and 100 dislocations has been studied. Boys under 10 years of age predominated. The majority of the injuries resulted from falls or road traffic accidents. Upper limb fractures occurred more commonly than those of the lower limbs or axial skeleton. Femoral shaft fractures were 2-1/2 to 5 times more common while femoral neck fractures were three to five times less common than in Americans. Dislocations were most common at the elbow, followed by the shoulder. Only 11.5% of the patients had open operations; the others were treated conservatively. The prognosis as regards survival and functional results was very good, but malunion was the most common complication.

Adolescent↗