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Biomedical subjects

W Wapner

Publications and source records attributed to W Wapner.

10 recordsLinked to original sources

The contribution of the right hemisphere to the organization of paragraphs.

Patients with unilateral right-hemisphere lesions performed significantly worse than normal controls in arranging the mixed-up sentences of stories. This impairment was not restricted to paragraphs conveying primarily spatial information, but occurred on other types of paragraphs as well. Nonspecific deficits of brain injury were ruled out as possible alternative explanations for the patients' difficulty on the task. The organization of language at the paragraph level may depend on right-hemisphere functioning.

Brain Damage, Chronic↗

Sensitivity to emotional expressions and situations in organic patients.

While numerous lines of investigation indicate the pivotal role of the right hemisphere in the apprehension and processing of emotional information, the specific contributions of facial recognition, other visual-spatial capacities, and a general understanding of emotionally-toned situations remains to be delineated. To secure information on the contributions of these various factors, matched groups of brain-damaged patients were required in a series of tests to match with one another faces of the same individual, facial expressions, pictorial versions of emotional situations, and linguistic versions of emotional situations. While patients with left-hemisphere damage evinced special difficulty with linguistically-presented stimuli, patients with right hemisphere damage exhibited an across-the-board reduction in emotional sensitivity, one not restricted to stimuli presented in the visual modality. In addition, right hemisphere patients also displayed a selective tendency to group together emotions of an opposite polarity (positively-toned with negatively-toned emotions). These results suggest that, in addition to its general importance in a range of emotional tasks, the right hemisphere is crucial for an appreciation of the structural relations which obtain among various emotions.

Adult↗

A note on patterns of comprehension and recovery in global aphasia.

Two tests of auditory comprehension (one probing knowledge of geographical locations, the other probing knowledge of familiar objects) were administered on two occasions to global aphasic patients. In addition to words drawn from the relevant lexical domains, nonsense words and words from inappropriate syntactic categories also were presented to the patients. The aphasic subjects attained more success rejecting nonsense words and words drawn from inappropriate syntactic categories than in comprehending the target words; in addition there was a consistent and surprising superiority in making correct localizations on a map as contrasted to localizing correctly familiar objects in a room. Similarly, patients' improvement across administrations was more pronounced in their heightened ability to reject the inappropriate terms rather than in increased capacity to make more accurate localizations of the target words. Overall, improvement was modest and virtually equivalent on the two measures of auditory comprehension.

Aphasia↗

Visual agnosia in an artist.

This report describes a 73 year old left-handed male artist who presented with agnosic symptoms following an occipital cerebral vascular accident. Against a background of a memory disturbance, but otherwise essentially intact linguistic and cognitive capacities, the patient was generally unable to identify single objects on visual presentation, and displayed marked difficulty in interpreting complex objects, depicted scenes, and partially occluded figures. The patient's preserved ability to recognize geometric forms, to perceive optical illusions, and to copy designs, and objects with considerable accuracy suggested the clinical picture of visual agnosia. An examination was undertaken of the effects of this recognition disorder on the artist's capacity to draw. Despite an inability to recognize an object or scene, the patient retained various techniques (perspective, shadowing, designation of texture) which allowed him to copy the display in a veridical fashion. When displays were recognized, or when the patient was given only the name of the object and asked to draw it, he adopted a less slavish approach, characteristic of his pre-morbid artwork. While his post-morbid drawings bore a strong similarity to his earlier works, such features as insufficient differentiation of figure from ground, over-elaboration of detail, and areas of neglect revealed the debilitating effects of the recognition disorder. Moreover, an examination of the patient's strategies revealed numerous compensatory verbal and motor procedures which guided his drawing. Acknowledgments. We wish to acknowledge Dr. Prather Palmer, J.R.'s neurologist, for his cooperation and for making available his very thorough examination notes. Thanks also to Dr. Kent Stevens for providing the stereograms, and to Dr. Frank Benson and Dr. Edgar Zurif for their helpful comments on the manuscript.

Aged↗

A study of confabulation.

Confabulation consequent to organic amnesia is a well-described clinical finding. A number of plausible theories of confabulation have been proposed, but the various claims and counterclaims have not been systematically tested. A standardized test battery that included four different kinds of questions plus measures of suggestibility and the tendency to utilize external cues was administered to ten amnesic patients who demonstrated varying degrees of confabulation. One additional patient, whose clinical condition changed dramatically during his hospital course, received the battery on a number of occasions. Differences among patients were found in overall performance, degree of confabulation, and ability to use cues. Hypothesized relationships between confabulation and suggestibility, degree of memory disorder, and degree of disorientation were not confirmed. However, confabulation proved to be strongly related to the inability to withhold answers, to monitor one's own responses and to provide verbal self-corrections. These results suggest a tentative model of the process of confabulation as well as a number of useful clinical signs indicationg recovery from amnesia.

Adult↗