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Biomedical subjects

W Wenzel

Publications and source records attributed to W Wenzel.

At least 19 recordsLinked to original sources
PubMed1987

[Aortic replacement with autologous free transplanted small intestine muscle in the dog].

Free transplantation of 60 grafts from muscle of small intestine has proved to work well for adequate replacement of larger vessels even in cases in which vessel beds were affected by infections. Patency of implants for smooth blood flow was angiographically verified in 86.7 per cent of all cases, whereas aneurysms occurred in only 15 per cent and septic complications in 11.7 per cent. With due consideration given to some technical aspects in preparation and implantation of transplants (complete removal of mucosa and pretension by something between 30 and 60 per cent), new therapeutic approaches might come to the fore to cope with infected synthetic protheses in vascular surgery.

Animals↗
PubMed1986

Replacement of dog's aorta by autologous intestinal muscle in the infected retroperitoneum.

The free transplant of intestinal muscle lacking mucosa into an infected vascular bed has been shown to be a suitable replacement for the aorta in dogs. This type of transplant is incorporated into the infected area and shows a high tolerance against progressive infection. Therefore, an autologous transplant may be suitable to ensure continuous blood flow during the healing phase of a deep infection when a synthetic prosthesis is unsuccessful.

Animals↗
PubMed1982

Visually evoked potentials in Friedreich's ataxia.

Visual evoked potentials to pattern-reversal stimulation have been recorded in 45 patients with Friedreich's ataxia. In six patients, no response could be obtained because of optic atrophy; altogether, pathological results were found in 25 patients (55%). Normal latencies were recorded in 20 patients (45%). No statistically significant connection could be drawn between the result of the VEP testing and visual acuity, age, or onset and duration of sickness, but there was a strikingly familiar accumulation of results. There is a good conformity between our results and the incidence of optic atrophy in later stages of the disease as shown by pathological-anatomical and epidemiological studies. We have demonstrated that optic nerve lesions in Friedreich's ataxia are not as rare as is frequently assumed and that the VEP is a valuable tool for detecting them. On the other hand, unfortunately, the VEP is of no help in the differential diagnosis of Friedreich's ataxia versus multiple sclerosis.

Adult↗
PubMed1981

[Clinical applications of visual evoked potentials for detection of chiasmal and postchiasmal lesions (author's transl)].

Visual evoked potentials (VEP) were recorded in 18 patients with pathologic processes confirmed by computerized tomography in the chiasmal (n = 9) and parietooccipital region (n = 9). Reactions from the right and left hemisphere could be recorded separately in spite of using a simple one-channel apparatus and electrodes only at Oz and Cz. In 17 cases changes of the VEP provided information concerning the localization and extension of the lesion. In chiasmal processes we found a prolongation of monocular latencies, and a delayed or extinguished reaction to half-field stimulation from temporal retinal areas. However, the VEP was often pathologic for half-field stimulation of the nasal hemiretina. Pathologic VEPs were not always accompanied by visual field defects. In contrary to patients with chiasmal processes no pathologic reaction could be found to full-field stimulation in parieto-occipital lesions. Only when the affected hemisphere was stimulated selectively were diminution of amplitudes, prolongation of latencies, or extinguished responses observed. The VEP changes were uniform despite the cause of the lesion (tumor, ischemia). In chiasmal and parieto-occipital processes the VEP supplements computerized tomography by detecting deficits in function. This method appears suitable for monitoring the course of disease before and after neurosurgery.

Brain Diseases↗
PubMed1980

'Normal' technetium bone scans in patients with acute osteomyelitis.

Several investigators have stressed the usefulness of the technetium bone scan in the early diagnosis of acute osteomyelitis. Seven patients with acute osteomyelitis had initial bone scans that were reportedly normal. The diagnosis was made as a result of either an abnormal gallium scan, positive cultures, or changes in follow-up roentgenograms. The explanation for the normal technetium scans is conjectural but may be related to compromised vascularity. A normal scan does not rule out acute osteomyelitis. If this diagnosis is strongly suspected, other diagnostic tests should be used.

Acute Disease↗