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Biomedical subjects

W Wey

Publications and source records attributed to W Wey.

At least 19 recordsLinked to original sources
PubMed1989

Magnetic resonance imaging for the assessment of lingual thyroid.

A 43-year-old woman was evaluated because of a round tumor at the base of the tongue. Scintigraphy with 131I showed radionuclide uptake over the posterior part of the tongue but no uptake at all at the usual pretracheal location. Magnetic resonance imaging revealed a well defined round mass of high signal intensity, which was clearly delineated from adjacent muscular tissue.

Adult↗
PubMed1989

Magnetic resonance imaging--a useful tool for airway assessment.

The case is presented of a 58-year old man with a malignant non-Hodgkin's lymphoma of the root of the tongue. Preoperative magnetic resonance imaging (MRI) proved extremely useful in the evaluation of the upper aerodigestive tract, by providing sagittal sections of the hypopharynx and the inlet of the larynx. Thus, a potentially difficult intubation was confirmed in a patient in whom other investigations would not have produced comparable conclusions. Difficulties in airway management were avoided by performing a tracheostomy under local anesthesia. This represents a novel application of MRI, which might contribute to the safety of airway management.

Airway Obstruction↗
PubMed1979

Suspicion of persistent or recurrent carcinoma of the larynx after radiation therapy.

At most interdisciplinary tumour centres, radiotherapy is of prime importance in the concept of therapy for the majority of the cases of laryngeal carcinoma treated, or it is even employed--exploratively and with curative intent--as the sole therapy at first. At all events initial radiotherapy occupies a dominant position today. Against this background the question is often discussed whether, after a 'low dose' has been attained (particularly in the case of a supraglottic tumour), a partial or total laryngectomy should be performed or the radiation dose substantially increased with the aim of obtaining a cure. However, the difficulties involved immediately after irradiation or later in recognizing a persistent or recurrent carcinoma and readily identifying it histologically may be very great. Various aspects of such situations--both diagnostic and therapeutic--are discussed in general and with reference to case histories.

Carcinoma↗
PubMed1979

[Bullous dermatoses in otorhinolaryngology (author's transl)].

The early clinical and histological diagnosis of acquired bullous dermatoses (pemphigus, bullous pemphigoid and the cicatricical pemphigoid of mucous membranes) may prove to be difficult when the disease is confined to the upper air and food passages. Histological differentiation between these diseases can also be difficult. In a number of cases it could be shown that the first signs of the disease were frequently mistaken for inflammatory conditions and that routine histological examination rarely confirmed the diagnosis. Only after immunohistological and immunoserological examination could the diagnosis be confirmed. In pemphigus, the treatment can be individually adapted to the titre of antibodies. The typical otorhinolaryngological findings in each of the three diseases are described.

Aged↗
PubMed1979

[The significance of papillary carcinoma of the thyroid for the ENT specialist (author's transl)].

The otorhinolaryngologist often encounters patients with pathological findings in the thyroid gland which may be overlooked if he is not aware. Alarming symptoms are rarely present in a goiter which is undergoing malignant change. Papillary and follicular carcinomas can exist over long periods of time as nodular goiters with globus symptoms or are discovered after cervical lymph nodes have appeared. The discovery of a goiter is thus of clinical importance regardless of the patient's age. Diagnostic iodine isotope scanning and cytological analysis is to be recommended as a matter of general policy. Excellent results in the treatment of papillary carcinoma can be obtained by subtotal thyroidectomy with modified neck dissection, followed by isotope elimination of remaining thyroid tissue.

Adolescent↗
PubMed1979

[Angio-immunoblastic lymphadenopathy (author's transl)].

The general clinical and pathological findings of angio-immunoblastic lymphadenopathy are reviewed and illustrated by a case-report with involvement of the tonsils. Our patient showed all the characteristic signs of this disease, including fever, pruritus, rash, generalized lymphadenopathy and hepatosplenomegaly. Histologically the wellknown triad of arborizing postcapillary vessels, proliferation of immunoblasts and plasma-cells, as well as deposition of PAS-positive interstitial material was found. Laboratory findings included a polyclonal hyperglobulinemia and a hemolytic anemia. Treatment consisted of corticosteroids and supportive medications. The prognosis is generally poor, with a median survival of 13 months. At present, the cause is unknown.

Adrenal Cortex Hormones↗
PubMed1978

[Tonsillar neoplasms].

While it is generally accepted that the treatment of choice in carcinoma of the tonsil is transcutaneous radiotherapy (including lymphatic drainage), opinion on additional surgical interventions is still divided. The possible operations are extended tonsillectomy followed by radical neck dissection or the composite operation with partial mandibulectomy. The importance of the composite operation for T3 stage tumors is emphasized. Chemotherapy (bleomycin) was rarely used in our patients, and only initially in extensive carcinoma.

Bleomycin↗
PubMed1978

[Phoniatric and laryngological aspects of systemic scleroderma (author's transl)].

Organs which contain collagen can have connective tissue new growth in systemic scleroderma. The occurrence of scleroderma of the larynx and organs of speech is rare. The disease develops in the mucous membrane in three stages: oedema; infiltration and induration; and atrophy. The oedema stage is generally the shortest. Three patients with systemic scleroderma with involvement of larynx and organs of speech have been seen. In one is described (graphically, sonographically and with stroboscopy) the progress of the disease from an initial severe hoarseness to later resolution of the oedema. In another patient involvement of the soft palate produced rhinolalia. In spite of the limitation of tongue movement in 2 patients there was no disorder of articulation.

Aged↗
PubMed1978

[Thyroid diseases. Impulses for the ORL-physician].

Diseases of the thyroid gland are not uncommon. Understanding the basics of physiology, pathophysiology, endocrinology and nuclear medicine, the otolaryngologist very often will uncover pathologic findings which he previously might have overlooked. A systematic evaluation of thyroid disorders will result in a worthwhile and fascinating collaboration among specialists in internal and nuclear medicine as well as specialists in surgery.

Diagnosis, Differential↗
PubMed1977

[Diagnostic and therapeutic aspects of solitary extramedullary plasmacytomas (author's transl)].

The rare solitary extramedullary Plasmacytoma is discussed and compared to the more common disseminated form. Based upon the pertinent literature, some diagnostic problems, clinical and pathological features as well as prognostic and therapeutic aspects of the solitary lesion in the ENT field are reviewed. In connection to one personal case, the authors analyze Trotter's Median Labiomandibular Glossotomy.

Brain Neoplasms↗
PubMed1977

[Clinical aspects of esophageal speech (author's transl)].

The quality of esophageal voice and speech after laryngectomy depends on several factors. Negative influences are produced by irradiation, resection of the hyoid bone and radical neck dissection. The factors important in esophageal speech were analyzed, with consideration given to the functional morphology of the pseudoglottis and the reconstructed hypopharynx. Phoniatric, laryngologic and radiologic aspects are considered.

Aged↗
PubMed1977

[Manifestations of paranasal sinus malignant lymphoma (author's transl)].

Malignant lymphomas rarely arise initially in the paranasal sinuses, although these may become involved at a later stage of the disease. Such cases have rarely been reported because the paranasal sinuses are seldom subjected to routine postmortem examination, and the clinical signs often resemble those of suppurative sinusitis. The present paper reports 3 patients in whom the paranasal sinuses were affected by a malignant lymphoma (chronic lymphatic leukaemia). The histological findings are illustrated and the pathogenesis discussed.

Aged↗
PubMed1976

[Late results in the removal of vocal-cord polyps].

A follow-up of 60 patients in whom polyps of the vocal cord have been removed between 1966 and 1974 is analyzed. Two thirds of the patients were male, mostly between 30 and 55 years of age. Most of the female patients were between 25 and 60. The most frequent localization was the typical one between the anterior and middle third of the vocal cord (47 patients). In 38 patients a direct laryngoscopy in local anaesthesia was performed; in 22 the removal of the polyps was done in microlaryngoscopy under general anaesthesia. The follow-up shows no recurrence. 55 patients had a clear voice, the remaining 5 showed signs of chronic laryngitis. It is concluded that microlaryngoscopy under general anaesthesia is indicated in cases of unfavourable anatomical configuration of the neck, sessile polyps or in cases where precise endoscopical manipulations are called for. The direct laryngoscopy remains an approved method in favourable cases, for instance pendular polyps, as these represent an affection of the vocal cord which shows no tendency to recurrence after mediculous removal.

Adult↗