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Biomedical subjects

W Wirth

Publications and source records attributed to W Wirth.

At least 37 records · Page 2Linked to original sources

Characterization of the collagen synthesized by cultured human smooth muscle cells from fetal and adult aorta.

Smooth muscle cells were grown from explants of the tunica media of fetal and adult human aorta. Collagen was isolated after incubation with [14C]glycine and was characterized by ion-exchange chromatography. All cells investigated synthesized two types of collagen: Type I (chain composition [alpha1(I)]2alpha2) and type III (chain composition [alpha1(III)]3). The collagen made by cells from adult donors contained approximately 70% type I and 30% type III collagen. This corresponds to the collagen composition in teh original tissue. No age-relate change in the type I/type III ratio was found with cells from donors between 9 and 67 years of age. On the other hand, the type III portion of the collagen made by fetal cells was markedly less (about 15-20% of total collagen).

Adult

[Complications in bilateral large lung cysts (author's transl)].

Complications in bilateral, congenital or acquired large cystic lesions in the lungs are a diagnostic and therapeutic problem. Early diagnosis and treatment is emphasized. When surgical treatment is necessary, decisions about the surgical procedures should be made knowing the in situ condition. Cooperation in decision making between bronchologist and thoracic surgeon is required.

Cysts

[The management of bronchial hemoptysis - case study (author's transl)].

Two case reports exemplify, that in patients with massive hemoptysis occuring in the bronchial system and owing to known or unknown causes, the emergency surgery must not to be delayed. In the case of minor relapsing hemoptysis, especially in old-age patients or borderline operability, the minimum surgical procedure is indicated after diagnosing and finding the localization of the hemorrhage.

Adult

[Primary extranodal lymphogranulomatosis of the flexura dodenal-jejunalis].

A primary extranodal lymphogranuloma of Hodgkin was found in the small bowel (PS II AE) of a 34-year-old man. Two years after radical surgery followed by local telecobalt therapy, the patient is in good health. The symptomatology, therapy and prognosis of this rare form of Hodgkin's lymphogranuloma are briefly reviewed.

Adult

Diffuse lymphangiomyomatosis.

A case of diffuse lymphangiomyomatosis with involvement of the large veins of the body is reported. The clinical, pathologoanatomic and especially the roentgenologic findings are described. Interstitial lung thickening, pleural effusions and spontaneous pneumothorax are findings which together with a stasis in the lymphatic system strongly suggest the diagnosis. The extensive involvement of the venous system supports the theory of a hamartomatous nature of the disease.

Adult