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W X Li

Publications and source records attributed to W X Li.

86 records · Page 5Linked to original sources
PubMed1986

The effect of passive smoking on children's pulmonary function in Shanghai.

We report the findings of a cross-sectional study of the relationship between passive smoking and pulmonary function of children in Shanghai, People's Republic of China. The 571 study subjects included 303 males and 268 females, ranging in age from 8 to 16 years, from a primary school and a secondary school at Xu-Hui District. Lung function tests were performed at the schools, and questionnaires were completed by parents. The father's cigarette smoking status during child's lifetime was linearly related to a decrease in the per cent predicted values of FEV1.0, MMEF and FEF 62.5-87.5% in total subjects; in school-girls, father's smoking status accounted for 0.5 per cent, 1.2 per cent, and 1.6 per cent of the total variation, respectively; the trend was less marked in boys. Other environmental factors considered in this study, i.e., educational level of the father, the use of coal or gas for cooking, the presence of patients with chronic respiratory diseases in the family, etc., did not seem to have any important role on the children's pulmonary function.

Adolescent↗
PubMed1982

[Inhibin].

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Animals↗
PubMedDate not supplied

Molecular cloning and sequence analysis of cDNAs encoding a beta-toxin-like peptide and two MkTx I homologues from scorpion Buthus martensii Karsch.

Three full-length cDNAs, one encoding the precursor of a beta-toxin-like peptide (named BmKBT) and the other two encoding those of (MkTx I) homologues (named MkTx II and MkTx III, respectively), were isolated from a venom gland cDNA library of the Chinese scorpion Buthus martensii Karsch, by screening with a cDNA fragment generated by PCR. The encoded precursor of BmKBT contained 83 amino acid residues including a signal peptide of 19 residues, a mature peptide of 63 residues and an extra basic residue (Lys) which have to be removed in the processing step. The deduced amino acid sequence of BmKBT showed 52% homology to that of beta-neurotoxin TsVII isolated from scorpion Tityus serrulatus. However, the positions of disulfide bridges have a little variation between the two peptides. The precursors of MkTx II and MkTx III both contained 85 amino acid residues including a signal peptide of 19 residues, a mature peptide of 64 residues and two extra residues (Gly-Arg) which have to be removed in the processing step, too. There was high sequence similarity (90%) between the two peptides. The sequences of mature MkTx II and MkTx III were highly homologous with MkTx I isolated from scorpion Buthus martensii Karsch, both showing 90% identities.

Amino Acid Sequence↗
PubMedDate not supplied

Molecular cloning and genomic organization of a K(+) channel toxin from the Chinese scorpion Buthus martensii Karsch.

A full-length cDNA encoding the precursor of a K(+) channel toxin (BmTX2) was first isolated from a venom-gland cDNA library of the Chinese scorpion Buthus martensii Karsch. The precursor is composed of a signal peptide of 21 residues and a mature toxin of 37 residues with three disulfide bridges. The genomic gene of BmTX2 was also cloned and sequenced. It consisted of two exons, disrupted by an intron of 81 bp inserted in the region encoding signal peptide.

Amino Acid Sequence↗