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Biomedical subjects

W Zoch-Zwierz

Publications and source records attributed to W Zoch-Zwierz.

At least 19 recordsLinked to original sources

[Immunoglobulin E and eosinophils in urine of children with bronchial asthma].

Excretion IgE and eosinophils was assayed in the urine of 25 children with bronchial asthma during attack (I) after regression of symptoms (II) and in a group of healthy children aged 4-15 years. Three healthy children (12%) excreted trace amounts of IgE and single eosinophils to urine. In the group of sick children during attack (I), 20 children (80%) excreted IgE in urine, 10 children (40%) excreted eosinophils. Thirteen children (52%) had nocturia, dysuria or erythrocyturia of unknown cause. After regression of acute symptoms of asthma (II) IgE in urine was excreted in smaller amounts than in (I) by 60% of the children, while eosinophils by 24% children. In the II investigation, 8 children (32%) still had nocturia. It was found that IgE and eosinophils are present in the urine of children with bronchial asthma, regardless if symptoms from the urinary tract are present or not.

Adolescent

[Anomalies of the cervical spine in children].

Two children are presented with congenital anomalies of the cervical spine and associated malformations of the nervous and urinary systems. The attention is paid to the usefulness of the cervical spine assessment in children in cases of recurrent cerebellar manifestations of unclear aetiology or combined malformations of the urinary system.

Abnormalities, Multiple

[Evaluation of N-acetyl-beta-D-glucosaminidase (NAG) and its isoenzyme activities in the urine of children with primary and secondary hypertension].

The total activity of N-acetyl-beta-D-glucosaminidase (NAG) and its isoenzymes A and B was determined in the urine of 18 children aged 9-18 years with essential hypertension and 21 with nephrogenic hypertension. The results were compared with those in a control group of 30 healthy children. The obtained results show that in children with stabilized hypertension (above the 95 centile) of essential type the proportion (above the 95 centile) of essential type the proportion of urinary isoenzymes are changes, with higher activity of the B isoenzyme. On the other hand, in children with nephrogenic hypertension the total activity and the activity of the B isoenzyme are increased. After reduction of blood pressure following hypotensive treatment (below the 90th centile) the activity of NAG and its isoenzymes was again normal in essential hypertension and was much reduced in nephrogenic hypertension. The study demonstrated that hypertension leads to transient damage to the proximal tubules which is reversed by effective hypotensive treatment.

Acetylglucosaminidase

[Familial occurrence of central diabetes insipidus].

Two cases are presented of familial diabetes insipidus with analysis of pedigree involving four generations. The analysis of diabetes insipidus occurrence in this family indicates the autosomal dominant type of inheritance.

Adult

[Clinical results of the treatment of bacterial infections in children with ceftazidime].

Ceftazidime (Fortum-Glaxo) was administrated to 19 children with urinary tract infections and to 21 children with pneumonia. Clinical symptoms of the infections resolved in 17 children (89%) with the urinary tract infections treated with ceftazidime within 4 days. The remaining children (11%) recovered after 7 days of therapy. Clinical symptoms of pneumonia resolved in 19 children (90%) within 7 days of the treatment. A significant improvement was achieved in the remaining 2 children after 10 days of the treatment.

Adolescent

[The NBT test in bacterial infections complicating prednisone-treated nephrotic syndrome].

The spontaneous nitroblue tetrazolium reduction test was done in children with nephrotic syndrome treated with prednisone and with secondary bacterial infections and in children with urinary tract infections not treated with prednisone. In healthy children 9.0 +/- 1.3% of polymorphonuclear leucocytes in peripheral blood showed presence of deposits in the NBT test. In children not treated with prednisone the number of NBT (+) leucocytes was increased over fourfold. The value of the NBT test was highest at the beginning of the disease. In children treated with prednisone the value of the NBT test increased slowly. The highest results were obtained in the second week of infection treatment. In relation to controls the proportion of NBT (+) test in peripheral blood was increased threefold.

Bacterial Infections