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W de Riese

Publications and source records attributed to W de Riese.

24 records · Page 2Linked to original sources

Indication of radical cystectomy in patients with carcinoma of the bladder.

We report on 64 patients subjected to radical cystectomy; 56 had carcinoma and 8 had non-tumorous indications (contracted bladder, exstrophy of the bladder). Indications, early and late results are discussed. In case of malignancy the rate of recurrences in early stages was about the same as in advanced stages. So it is not possible to say anything definitely about the individual prognosis of recurrence in patients undergoing radical cystectomy. It is easier to justify palliative cystectomy because of the relatively low risk of operation.

Carcinoma, Transitional Cell↗

Adenocarcinoma in extrophy of the bladder. A case report and review of the literature.

There have been 81 cases of carcinoma in extrophied bladder described previously. We describe another such case. It demonstrates the problem of early diagnosis of carcinoma in extrophy of the bladder and the therapeutic consequences of an early cystectomy. In accordance with current literature we illustrate the theories on oncogenesis, and review the cases previously published.

Adenocarcinoma↗

Intrascrotal metastases from renal cell carcinoma.

This is an up-to-date report about two patients suffering respectively from testicular and epididymal metastases of a renal adenocarcinoma in the condition following tumour nephrectomy in anamnesis. It is a survey on literature including the number of cases published.

Aged↗

[In vitro sensitivity testing of human kidney tumors to cytostatic drugs with a rapid in vitro test].

We present a new modified in vitro culture assay for primary human renal cell carcinoma similar to the 'soft agar clonogenic assay'. However, the carrying out and expense of metrology are more simplified, allowing tumor-specific chemotherapeutic drug sensitivity testing under easier conditions. Twelve different samples of human renal carcinoma and one sample of a transitional cell carcinoma of the renal pelvis were tested for in vitro chemotherapy sensitivity using this modified colony-forming assay. The rate of tumor cells establishing in culture was 100%. Corresponding to clinical experience we observed a nearly complete resistance to the cytotoxic effects of standard chemotherapeutic agents at usual plasma concentrations in man. Only higher concentrated chemotherapeutic drugs showed in vitro therapeutic effects. The assay described here lasts about 7 days, which is beneficial from the clinical point of view. The modification of this in vitro chemotherapeutic drug treatment is unlimited for plasma concentration and duration of standard and experimental chemotherapeutic agents, drug combination and so on. So we have interesting scientific steps which could not have been undertaken under usual clinical-empirical conditions.

Adenocarcinoma↗