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W van der Merwe

Publications and source records attributed to W van der Merwe.

5 recordsLinked to original sources

Intra-operative pneumatic tourniquet--perceptions of use and complications in the orthopaedic community of South Africa.

OBJECTIVES: To assess views on use, maintenance and side-effects of the pneumatic tourniquet in the South African orthopaedic community. METHODS: A census-type questionnaire study was conducted of all 475 orthopaedic surgeons registered with the Orthopaedic Association of South Africa during 1993/94. The chi-square test was used to determine statistical significance between different groups of respondents. RESULTS: Seventy-seven per cent of the questionnaires were returned. Ninety-nine per cent of respondents used a pneumatic tourniquet. Eighty-four per cent believed that the tourniquet may damage underlying tissue both as a result of applied pressure effects and ischaemic consequences. Fifty-four per cent of respondents personally checked the calibration of the pneumatic tourniquet, although 76% of respondents believe that the apparatus needs to be checked at least once per month. More respondents who did not check the tourniquet apparatus than respondents who did check it believe that applied pressure does not cause tissue damage (P < 0.001), that the operating room technician or hospital engineer should be responsible for checking equipment (P < 0.001), and that equipment did not need to be checked more than once every 6 months (P < 0.001). CONCLUSIONS: Although most orthopaedic surgeons are aware of the pneumatic tourniquet's side-effects, a minority appear to be unaware of the hazards of excessive applied pressure alone or excessive applied pressure caused by use of faulty equipment. It needs to be emphasised to these surgeons that regular checking of the pneumatic tourniquet apparatus is necessary in order to prevent postoperative complications ascribed to use of the tourniquet.

Bandages↗

Hospital admissions for adverse reactions to drugs and deliberate self-poisoning.

In a prospective study of 300 patients, 14 admissions (4,6%) were considered to be related to adverse drug reactions. A further 29 admissions (9,6%) were due to self-poisoning with drugs prescribed for therapeutic purposes. Agents causing adverse reactions were predominantly cardio-active drugs and anticoagulants. Mean duration of hospital stay in this group of patients was 8,3 days (range 2-18 days); there were no deaths. Tranquilizers and antidepressants were most commonly used for self-poisoning. Duration of admission in these patients was much shorter than in the previous group--mean 1,8 days (range 1-5 days), and there was 1 death. To the best of our knowledge, this is the first reported series of such cases in South Africa. It shows that drugs are an important cause of morbidity in hospital patients in the RSA.

Adolescent↗

Hepatic enzymes, their induction and usefulness in predicting maximal serum bilirubin levels in premature newborn infants.

Sixty-seven babies were utilized to (a) document the serum bilirubin lowering effect and safety of a phenobarbitone and nikethamide combination in neonatal hyperbilirubinaemia of non-hemolytic origin; (b) determine whether birthweight and/or SGOT, SGPT or SGGT activity on day one of life correlated with the maximum serum bilirubin level achieved; and (c) investigate the pattern of hepatic enzyme levels in serum under normal conditions anf following drug induction. Results indicate a significantly lower serum bilirubin level in the treated group of babies. Birthweight and day one SGGT levels, and SGGT/birthweight ratio correlated well with the maximum serum bilirubin reached, the latter ratio being particularly useful in predicting the degree of hyperbilirubinaemia.

Alanine Transaminase↗