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Biomedical subjects

Walter Krause

Publications and source records attributed to Walter Krause.

22 records · Page 2Linked to original sources

Distress of infertile males after fertility workup: a longitudinal study.

OBJECTIVE: Former research has revealed that distress declines after fertility workup. It was the aim of the present study to explore whether this decline depends on such aspects as the diagnosis or the former usage of fertility services. METHODS: Patients attending an andrological clinic filled out questionnaires on distress and coping behaviour at clinic attendance as well as 4 months later. RESULTS: For distress scores there was an interaction between time and former usage of infertility services, indicating that only first-time consulters show a decline in distress after fertility workup. No impact of diagnosis on distress scores could be detected. Generally, patients showed a decrease of active coping behaviour after fertility workup, along with a greater tendency to accept infertility as one's fate. CONCLUSION: The findings indicate that there are different processes working in first-time and repeat consulters with respect to the course of distress.

Adaptation, Psychological↗

Genital Paget's disease in a man.

Pagetoid cells are large intraepidermal cells which spread intraepidermally. We report a 67-year old Caucasian male, who presented for the first time in 1993 with a long-standing pruritic lesion at the scrotum. He was treated for several years by antiinflammatory ointments. Only in July 2003 was a biopsy taken for the first time. The histopathological evaluation revealed the diagnosis of an extramammary Paget's disease (EMPD). Pagetoid cells are large intraepidermal cells with a large nucleus and ample cytoplasm. EMPD consists of primary malignant cells of epidermal origin, but in rare cases, pagetoid cells may also originate from carcinomas with epidermotropic growth. EMPD is a slowly progressing disease, but invading and metastasing tumors may also develop. Considering the good prognosis with long-term survival, nonsurgical modalities should be considered as primary treatment for noninvasive EMPD.

Administration, Topical↗