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Biomedical subjects

Weiqi Wang

Publications and source records attributed to Weiqi Wang.

7 recordsLinked to original sources

An adaptive clutter rejection method based on AR model in color flow imaging.

The ultrasound Doppler signal scattered from blood is heavily corrupted by the clutter signal reflected from slowly moving muscular tissue. The Doppler frequency shift of blood flow and clutter in different parts of human body greatly changes. Therefore, if a fixed wall filter is selected, the optimal filtering effect can not be attained. An adaptive clutter rejection method is proposed in this paper, which consists of a weak clutter rejector and a 2-order AR estimator. The clutter and blood power thresholds were preliminary defined in the weak clutter rejector. The echo power is compared with the two pre-defined thresholds, and the result was used to select an appropriate wall filter. The output of the weak clutter rejector is estimated by a 2-order AR estimator and two poles are acquired. The low frequency pole denotes the clutter signal and the high frequency pole denotes the blood signal. Before the AR estimation, a static signal is added to avoid producing split spectral peaks. It is illustrated in the simulation that the proposed method can detect the slower blood flow with smaller variance compared with the traditional wall filtering method.

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Doppler ultrasound signals simulation from vessels with various stenosis degrees.

As a non-invasive method, the Doppler ultrasound technique is used to detect the vessel stenosis. To search for characteristics of Doppler ultrasound signals sensitive to the stenosis, a computer simulation approach is proposed in this paper to generate Doppler ultrasound signals from vessels with various stenosis degrees. The blood flow velocity distribution in a stenosed vessel is firstly calculated using the transient finite element method (FEM). Then the power spectral density of Doppler signals is estimated using the overall-distribution nonparametric estimation method. Finally Doppler signals are generated using the cosine-superposed method. The proposed approach is proved to be useful for simulating Doppler ultrasound signals from vessels with various stenosis degrees. It is also shown that characteristics of Doppler ultrasound signals may be used to estimate the vessel's stenosis degree.

Algorithms↗

A quadrature demodulation method based on tracking the ultrasound echo frequency.

The ultrasound echo attenuation depends on frequency, propagating depth and tissue characteristics. Thus, the attenuation dependent on frequency results in a larger attenuation of high frequencies than lower when the wave propagates through the tissue. As a result, the central frequency of the echo generates the increasing downshift with the increasing of depth. In the traditional I/Q demodulation method, it is assumed that the central frequency of the echo is the same as the transmitting frequency and unchanged all time. The assumption directly causes that the acquired I/Q signals are not perfect baseband ones but biased due to the echo attenuation. In addition, the unreasonable assumption will keep the echo from getting better signal-to-noise ratio. A quadrature demodulation method based on tracking the ultrasound echo frequency is proposed in this paper. The method consists of the traditional I/Q demodulator, the frequency tracking module, the phase compensation module and the dynamic filtering module. The outputs of I/Q demodulator are biased. Autocorrelation technique is utilized in the frequency tracking unit to estimate the frequency bias according to the outputs of I/Q demodulator. The estimated bias feeds to the phase compensation unit which can eliminate the frequency bias by simple trigonometric function transform. The compensated signals feed to the dynamic filter and are further processed. The bandwidth of the dynamic filter decreases with the increasing of the depth, which makes the echo acquire better SNR in different depth. The efficiency of the proposed method is testified by both simulations and experiments.

Algorithms↗

The wall signal removal in Doppler ultrasound systems based on recursive PCA.

In Doppler ultrasound (US) systems, a high-pass filter is usually employed to remove the wall component from the blood flow signal. However, this will lead to the loss of information from the low velocity flow. In this paper, an algorithm based on the principal components analysis (PCA) is proposed, in which singular value decomposition (SVD) is used to extract the main component from the mixed signals. Furthermore, the recursive process is incorporated into the PCA method to improve the performance of wall signal removal. This approach and the traditional high-pass filtering one are, respectively, applied to analyze the computer-simulated in vitro and in vivo Doppler US signals. With the proposed method, the wall signal can be removed while a large portion of low-velocity blood signal remains. Comparison experiments show that this novel approach can satisfy the requirements of Doppler US system and is practicable under a broad range of measurement conditions. Because this algorithm is based on real data, it is currently applied to unidirectional signals.

Adolescent↗

Estimating coronary artery lumen area with optimization-based contour detection.

A modified optimization-based contour detection method was presented to compute the lumen area of the coronary artery from intravascular ultrasound (IVUS) video images. First, the search range for the artery inner wall was determined based on the continuity of IVUS video frames. Next, the internal and external energy were calculated to describe the smoothness of the arterial wall and the grayscale variation of ultrasound images, respectively. Here, a novel form of the external energy which combines the gradient and variance of the intensity of image in the radial direction was used. Finally, the minimal energy path based on the optimum contour of the artery wall was obtained using circular dynamic programming (DP). By the comparison with the typical DP procedure using the traditional external energy form, based only on the image gradient, the reliability of this modified method is considerably improved in the measurement of coronary artery lumen area.

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[Wavelet feature extraction and classification of Doppler ultrasound blood flow signals].

The maximum frequency waveforms of Doppler ultrasound blood flow signals were analyzed using a multi-scale wavelet transform. The variation of maxima of wavelet transform modulus under various scales was extracted from the time-scale representation. This novel approach was applied to the analysis of Doppler signals from carotid blood flow. It was found that the shape of this variation from cases with normal cerebral vessels differed from those associated with abnormal cases. The curve was fitted by a polynomial, and its coefficients were put into a back-propagation (BP) neural network to make a classification. The clinical experiments showed that this approach got good performance and could be a new means in the clinical diagnosis of cerebral vascular disease.

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