Complete, incomplete or no myocardial revascularization.
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Coronary Disease↗
Biomedical subjects
Whady Armindo Hueb
Publications and source records attributed to Whady Armindo Hueb.
[Comparative study of the results of coronary artery bypass grafting and angioplasty for myocardial revascularization in patients with equivalent multivessel disease].
OBJECTIVE: To investigate the relative efficacy of different therapeutic strategies in patients with symptomatic multivessel coronary artery disease with preserved ventricular function. The primary objectives were defined as a combination of death of cardiac origin, acute myocardial infarction (AMI), and refractory angina that required revascularization, and the secondary objectives were defined as anginal state and exercise-induced ischemia. METHODS: Of the 20,769 patients assessed on cine coronary angiography at InCor, 210 were chosen for this study and were randomized either for coronary artery bypass grafting (CABG, n = 105) or transluminal coronary angioplasty (TCA, n = 105). RESULTS: A mean of 3.2 +/- 0.8 vessels received anastomoses and 2.1 +/- 0.8 were successfully dilated in the CABG and TCA groups, respectively. In a 5-year follow-up, the rates of events in the CABG and TCA groups were, respectively: mortality, 9.52% and 12.38%; acute myocardial infarction, 2.85% and 8.57% (P = 0.0668); and additional intervention, 2.85% and 24.76% (P < 0.001). The survival rate was 88.39% for CABG and 84.93% for TCA; the respective AMI-free percentages were 84.40% and 77.40%. In the CABG and TCA groups, 62% and 60% of the patients had no angina, respectively. The exercise tests were considered nonischemic in 62.5% and 62.1% of the patients in the CABG and TCA groups, respectively. CONCLUSION: In multivessel patients, compared with angioplasty, coronary artery bypass grafting was associated with a lower incidence of long-term events and a reduced need for new interventions (P = 0.001).
Adult↗
Coronary heart disease clinical manifestation and risk factors in Japanese immigrants and their descendents in the city of São Paulo.
OBJECTIVE: To assess whether a difference exists in coronary heart disease clinical manifestations and the prevalence of risk factors between Japanese immigrants and their descendents in the city of São Paulo. METHODS: Retrospective analysis of coronary artery disease clinical manifestations and the prevalence of risk factors, comparing 128 Japanese immigrants (Japanese group) with 304 Japanese descendents (Nisei group). RESULTS: The initial manifestation of the disease was earlier in the Nisei group (mean=53 years), a difference of 12 years when compared with that in the Japanese group (mean=65 years) (P<0.001). Myocardial infarction was the first manifestation in both groups (P=0.83). The following parameters were independently associated with early coronary events: smoking (OR=2.25; 95% CI=1.35-3.77; P<0.002); Nisei group (OR=10.22; 95% CI=5.64-18.5; P<0.001); and female sex (OR=5.04; 95% CI=2.66-9.52; P<0.001). CONCLUSION: The clinical presentation of coronary heart disease in the Japanese and their descendents in the city of São Paulo was similar, but coronary heart disease onset occurred approximately 12 years earlier in the Nisei group than in the Japanese group.
Adult↗
Detection of retained surgical sponge by transthoracic and transesophageal echocardiography.
We describe an unusual case of extracardiac mass in a patient who was assymptomatic and submitted to an open-chest coronary artery bypass operation 5 years previously. Transthoracic and transesophageal echocardiography revealed a rounded mass compressing the right atrium with a thick contour surrounding a heterogeneous center, suggestive of foreign body. Magnetic resonance imaging identified the mass as a pericardial cyst. Operation revealed a fibrinous cyst encapsulating a sponge. This case illustrates the central role of echocardiography for the diagnosis and treatment of patients with suspected retained surgical sponges.
Chronic Disease↗
[Quality of life in patients with coronary artery disease: comparison between the genders].
OBJECTIVE: To analyze the quality of life of people with coronary artery disease (CAD) who underwent distinct therapeutic interventions and compare the possible differences between genders. METHODS: This study comprised 542 subjects, 376 men (58.5 +/- 8.7 years) and 166 women (61.8 +/- 9.2 years), with CAD who underwent surgical, medical treatment or angioplasty. Quality of life was assessed with The Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) administered at the beginning of treatment and after 6 and 12 months. The applied statistical method was the ANOVA test. RESULTS: Those who underwent surgical treatment had scores of 46, 63, 68, for physical components; 52, 65, 62 for medical treatment, and 57, 66, 70 for angioplasty, respectively, in the initial, six, and twelve months phases. For mental components, results were 58, 71, 74 for the surgical intervention; 61, 69, 69 for the medical treatment, 64, 74, 74 for angioplasty. The differences over time and between treatments reached a statistical significance (p<0.001). In comparing genders, physical component scores in men were 56*, 69, 77*, and 41*, 64, 62* in women, respectively; mental component scores in men were 61*, 73, 80* and 51*, 68, 62* in women (*p<0.0001). CONCLUSIONS: Subjects who underwent surgical treatment had the most favorable evolution. Men when compared to women had a better quality of life in the beginning of treatment with a progressive improvement after six and twelve months, while women, after an improvement at six months, presented a decrease at twelve.
Adult↗