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William Bell

Publications and source records attributed to William Bell.

4 recordsLinked to original sources
PubMed2004

A detachable porous vaginal mold facilitates reconstruction of a modified McIndoe neovagina.

OBJECTIVE: To release a new design for a detachable porous vaginal mold to facilitate reconstruction of a modified McIndoe vaginal mold. DESIGN: We constructed a detachable, porous vaginal mold with a plastic laboratory centrifuge tube with multiple holes throughout the entire tube. SETTING: Patients in a national tertiary medical center. PATIENT(S): Four patients of congenital vaginal agenesis received the modified McIndoe procedure. INTERVENTION(S): Two full-thickness skin grafts removed from the inguinal region were used to cover the detachable porous plastic vaginal mold; the mold was then inserted into the neovaginal cavity and kept in place by sutures between the mold and labia majora. The vaginal mold was removed on day 12 after the operation. All patients adhered to the follow-up instructions. MAIN OUTCOME MEASURE(S): Description of the accessibility of a neovaginal mold. RESULT(S): The vaginal mold is helpful in taking care of the vaginal wound in that it allows easy removal of wound secretion and local cleansing douches. All grafts took completely and recovered well. No detachment of the graft occurred. CONCLUSION(S): The advantages of the detachable porous vaginal mold made from a plastic centrifuge tube are that it is readily available, allows for easy wound care, and, as a fixed point, prevents graft detachment or inversion and thus may lead to a promising result for a modified McIndoe vaginal reconstruction.

Adolescent↗
PubMed2002

Sensitivity and specificity of western blot testing of cerebrospinal fluid and serum for diagnosis of equine protozoal myeloencephalitis in horses with and without neurologic abnormalities.

OBJECTIVE: To determine sensitivity and specificity of western blot testing (WBT) of CSF and serum for diagnosis of equine protozoal myeloencephalitis (EPM) in horses with and without neurologic abnormalities. DESIGN: Prospective investigation. ANIMALS: 65 horses with and 169 horses without neurologic abnormalities. PROCEDURE: CSF and serum from horses submitted for necropsy were tested for Sarcocystis neurona-specific antibody with a WBT. Results of postmortem examination were used as the gold standard against which results of the WBT were compared. RESULTS: Sensitivity of WBT of CSF was 87% for horses with and 88% for horses without neurologic abnormalities. Specificity of WBT of CSF was 44% for horses with and 60% for horses without neurologic abnormalities. Regardless of whether horses did or did not have neurologic abnormalities, sensitivity and specificity of WBT of serum were not significantly different from values for WBT of CSF. Ninety-four horses without EPM had histologic evidence of slight CNS inflammation. CONCLUSIONS AND CLINICAL RELEVANCE: The low specificity of WBT of CSF indicated that it is inappropriate to diagnose EPM on the basis of a positive test result alone because of the possibility of false-positive test results. The high sensitivity, however, means that a negative result is useful in ruling out EPM. There was no advantage in testing CSF versus serum in horses without neurologic abnormalities. Slight CNS inflammation was common in horses with and without S neurona-specific antibodies in the CSF and should not be considered an indication of CNS infection with S neurona.

Animals↗
PubMed2000

Somatotype and angiographically determined atherosclerotic coronary artery disease in men.

The relationship between somatotype and somatotype components with coronary artery disease (CAD) and regional adiposity was considered in 58 males (age 60.2 +/- 9.4 years) undergoing investigative coronary angiography for suspected atherosclerotic CAD. Severity of CAD was determined in terms of both the degree of stenosis and the anatomical position of the lesions on the coronary arteries (myocardial score). Six patients had negative angiographic findings but three of these had impaired left ventricular function as determined by left ventriculography. The mean (+/-SD) somatotype of the group was 5.7 / 5.6 / 1.2 (1.7 / 1.4 / 1.0), illustrating a clear dominance of the first two somatotype components. Canonical correlation analysis showed that somatotype was not significantly related to the angiography results (P > 0.05). However, correlations between the somatotype components and the angiography results with their respective first canonical variates showed that the somatotype variate was one of high mesomorphy and low ectomorphy and the angiography variate was essentially one of a high myocardial score. After adjustment for the confounding interrelationship among the somatotype components, endomorphy was significantly correlated with abdominal circumference (r = 0.65, P < 0.001), the abdomen-to-hip ratio (r = 0.53, P < 0.001) and the abdominal sagittal diameter (r = 0.60, P < 0.001). Mesomorphy was not related to these indicators of android or abdominal adiposity following partial adjustment. Ectomorphy was inversely related to the indices of general and regional adiposity. This study suggests that adiposity and muscularity are important features in terms of increased CAD risk, whereas linearity is beneficial. Am. J. Hum. Biol. 12:128-138, 2000. Copyright 2000 Wiley-Liss, Inc.

Journal Article↗