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Biomedical subjects

William P Hogle

Publications and source records attributed to William P Hogle.

7 recordsLinked to original sources

The state of the art in radiation therapy.

OBJECTIVES: To describe the modalities used to administer radiation therapy and discuss the acute effects and long-term survivorship issues experienced by patients who receive radiation therapy. DATA SOURCES: Radiation oncology, surgical, and oncology nursing journals, textbooks, electronic resources. CONCLUSION: New technology and state-of-the-art equipment has resulted in improved treatment modalities, thereby expanding traditional treatment paradigms and exploring new frontiers. IMPLICATIONS FOR NURSING PRACTICE: It is critical that oncology nurses remain cognizant of advanced technology and its influence on treatment outcomes and patient toxicity. Such knowledge will better serve patients and hopefully influence evidence-based treatment interventions.

Aftercare↗

Abarelix (plenaxis).

Explore the source record for details and available documents.

Antineoplastic Agents↗

Advances in brachytherapy: new approaches to target breast cancer.

Advances in breast brachytherapy techniques have led to the development of new approaches for treatment of patients with early-stage breast cancer. This article reviews the indications, clinical utility, and nursing interventions for the Mammosite Radiation Therapy System (Proxima Therapeutics, Alpharetta, GA) and INTRABEAM (Photoelectron Corporation, North Billerica, MA) radiation therapy system. Each uses a slightly different approach to provide definitive radiotherapy to the breast tumor bed following excision. Radiation oncology nurses should have an understanding of how each system works to provide optimal care as it pertains to education, side effect management, and catheter care for patients receiving each of these types of radiotherapy. These innovative alternatives will greatly reduce required treatment time if clinical studies find them to be equivocal or superior to traditional radiation therapy techniques. These treatment approaches also may make radiation treatments more convenient for women with early-stage breast cancer.

Brachytherapy↗

Malignant hemangiopericytoma: a clinical overview and case study.

Although unusual, hemangiopericytoma (HPC) can be considered benign or malignant depending on histologic features. In some cases, malignant HPC can behave as high-grade sarcomas. When HPC is deemed malignant, radical surgical excision is the treatment of choice. Adjuvant chemotherapy and radiation therapy offer limited success in patients with this malignancy. This article details a case study of a man with metastatic malignant HPC that spanned 25 months and three major cancer centers. Throughout the case study, chemotherapy, radiation therapy, and an experimental agent were employed to attempt to achieve control of the aggressive disease. Often, patients with HPC need a multidisciplinary approach to their care that requires involvement of nutritional and social services, behavioral medicine, and home or hospice care as appropriate. A better general understanding of this disease process is needed to meet the needs of patients with malignant HPC.

Antineoplastic Combined Chemotherapy Protocols↗