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Biomedical subjects

William S Marras

Publications and source records attributed to William S Marras.

At least 19 recordsLinked to original sources

The effects of work experience, lift frequency and exposure duration on low back muscle oxygenation.

BACKGROUND: Previous studies have shown changes in low back muscle oxygenation after static muscle contractions or short-term dynamic lifting exertions. The aim of this study was to document the changes in low back muscle oxygenation during prolonged lifting activity over an entire workday as of function of work experience and lift frequency. METHODS: Four novice and six experienced subjects participated in a lifting study in which they lifted load with a given weight at one of five different frequencies (2, 4, 8, 10, 12 lifts/min) for an 8-h period. Oxygen saturation of the left and right erector spinae was measured continuously and non-invasively using near-infrared spectroscopy during each lifting session. FINDINGS: Exposure duration had a statistically significant effect on muscle oxygenation level (P<0.0001). Oxygen saturation in the erector spinae increased during the 8-h lifting period. As lift frequency increased, back muscle oxygenation in experienced subjects also increased. In general, the increase in muscle oxygenation for experienced subjects was less than that for novice subjects. INTERPRETATION: This study suggested that the requirement of oxygen for the low back muscle in a typical industrial lifting job increased over time and experienced workers responded differently from the novice subjects. These findings may provide more insight into the physiological changes of the working muscle and the potential risks of developing muscle injury.

Back↗

Spinal loading during manual materials handling in a kneeling posture.

Stooped, restricted, kneeling, and other awkward postures adopted during manual materials handling have frequently been associated with LBP onset. However, lift assessment tools have focused on materials handling performed in an upright, or nearly upright standing posture. Unfortunately, many of the tools designed to analyze standing postures are not easily adapted to jobs requiring restricted postures. Therefore, the objective of this study was to evaluate spinal loading during manual materials handing in kneeling postures and determine if those loads can be predicted using simple regression. An EMG-driven biomechanical model, previously validated for upright lifting, was adapted for use in kneeling tasks. Subjects knelt under a 1.07m ceiling and lifted luggage of six weights (6.8, 10.9, 15.0, 19.1, 23.1 and, 27.2kgf) to one of four destination heights (0, 25.4, 53.3, 78.7cm). Spine loading was significantly affected by both destination height and load weight. Destination height increased compression, AP shear and lateral shear by an average of 14.5, 3.7 and 6.6N respectively per cm height increase. Load weight increased compression, AP shear and lateral shear by an average of 83.8, 27.0 and 13.1N respectively per kgf lifted. Regression equations were developed to predict peak spine loading using subject height, load weight and destination height with R(2) values of 0.62, 0.51 and 0.57 for compression, AP and lateral shear respectively.

Adult↗

An exploratory study of loading and morphometric factors associated with specific failure modes in fatigue testing of lumbar motion segments.

BACKGROUND: There is currently little information regarding factors associated with specific modes of motion segment failure using a fatigue failure model. METHODS: Thirty-six human lumbar motion segments were fatigue tested using spinal compressive and shear loads that simulated lifting a 9 kg weight in three torso flexion angles (0 degrees, 22.5 degrees, and 45 degrees). Twenty-five segments failed via fatigue prior to the 10,000 cycle maximum. These specimens were visually inspected and dissected so that the mode(s) of failure could be determined. Failure modes included endplate fractures (classified into nine varieties), vertebral body fractures, and/or zygapophysial joint disruption. Logistic regression analyses were performed to determine whether certain morphometric variables, amount of motion segment flexion, disk degeneration scores, and/or loading characteristics were associated with the occurrence of specific failure modes. FINDINGS: Results indicated that stellate endplate fractures were associated with increased posterior shear forces (P < 0.05) and less degenerated discs (P < 0.01). Fractures running laterally across the endplate were associated with motion segments having larger volumes (P < 0.01). Endplate depression was more common in smaller specimens (P < 0.01), as well as those experiencing increased posterior shear force (P < 0.05). Zygapophysial joint damage was more likely to occur in a neutral posture (P < 0.01). INTERPRETATION: These results suggest that prediction of failure modes (e.g., specific endplate fracture patterns) may be possible (at least for older specimens) given knowledge of the spinal loads along with certain characteristics of the lumbar spine.

Aged, 80 and over↗

Torso flexion loads and the fatigue failure of human lumbosacral motion segments.

STUDY DESIGN: Spine loads associated with lifting a 9-kg weight were estimated at three torso flexion angles (0 degrees, 22.5 degrees, and 45 degrees), and lumbosacral motion segments were cyclically loaded using these loads until failure or to a maximum of 10,020 cycles. OBJECTIVES: To simulate the postures and loads experienced by the lumbar spine during repetitive lifting of moderate weights in different torso flexion postures, and to analyze the fatigue failure response of lumbosacral motion segments. SUMMARY OF BACKGROUND DATA: Previous fatigue failure studies of lumbar motion segments have not reproduced the combination of spinal postures, loads, and load rates anticipated in different torso flexion postures during lifting tasks characteristic of those in occupational settings. METHODS: Twelve fresh human lumbosacral spines were dissected into three motion segments each (L1-L2, L3-L4, and L5-S1). Motion segments within each spine were randomly assigned to a simulated torso flexion angle (0 degrees, 22.5 degrees, or 45 degrees) using a partially balanced incomplete block experimental design. Spinal load and load rate were determined for each torso flexion angle using previously collected data from an EMG-assisted biomechanical model. Motion segments were creep loaded for 15 minutes, then cyclically loaded at 0.33 Hz. Fatigue life was taken as the number of cycles to failure (10 mm displacement after creep loading). Specimens were inspected to determine failure mechanisms. RESULTS: The degree of torso flexion had a dramatic impact on cycles to failure. Motion segments experiencing the 0 degrees torso flexion condition averaged 8,253 cycles to failure (+/-2,895), while the 22.5 degrees torso flexion angle averaged 3,257 (+/-4,443) cycles to failure, and motion segments at the 45 degrees torso flexion angle lasted only 263 cycles (+/-646), on average. The difference was significant at P < 0.0001, and torso flexion accounted for 50% of the total variance in cycles to failure. CONCLUSIONS: Fatigue failure of spinal tissues can occur rapidly when the torso is fully flexed during occupational lifting tasks; however, many thousands of cycles can be tolerated in a neutral posture. Future lifting recommendations should be sensitive to rapid development of fatigue failure in torso flexion.

Aged↗

Functional impairment as a predictor of spine loading.

STUDY DESIGN: Spine loadings during a variety of lifting exertions were compared with individual torso kinematic abilities. Relationships were evaluated between these measures. OBJECTIVE: To determine if trunk kinematic status (functional impairment) is indicative of spine loading increases in patients with low back pain (LBP) compared to asymptomatic individuals. SUMMARY OF BACKGROUND DATA: Recurrent LBP is a common and costly problem that may be related to increased spine loads in those individuals with LBP. Previous studies suggest that patients with LBP had greater loading than their asymptomatic counterparts when performing work. However, we know little about how to identify when a patient with LBP can resume lifting tasks without having exaggerated spine loading. METHODS: Sixty-two patients with LBP and 61 who were asymptomatic were evaluated for signs of kinematic compromise (i.e., inability to generate normal trunk kinematic patterns) during a prelift test. All subjects were then asked to perform a variety of lifting exertions that varied in lift origin (region), lift asymmetry position, and weight lifted. An electromyography-assisted model was used to evaluate spine loading in each subject during the lifting exertions. Statistical models were used to assess the relationship between kinematic compromise and spine loading. RESULTS: Patients with LBP had greater spine loading as well as greater kinematic compromise. The degree of kinematic compromise was related to the degree of spine loading increases in those individuals with LBP. A statistical model was developed that was able to describe 87% of the variability in compression, 61% in anteroposterior shear, and 65% in lateral shear. CONCLUSIONS: Those patients with greater kinematic compromise used higher levels of antagonistic muscle coactivation that not only reduced trunk motion but also resulted in increases in spine loading. Given the degree of kinematic compromise and the lifting task conditions, a method has been devised to predict the increase in spine loading above and beyond that of an asymptomatic individual when performing typical materials handling tasks.

Biomechanical Phenomena↗

The effect of ergonomic interventions in healthcare facilities on musculoskeletal disorders.

BACKGROUND: The high incidence of musculoskeletal disorders (MSDs) among healthcare workers suggests that the introduction of ergonomic interventions could be beneficial. While laboratory studies have clearly documented the efficacy of ergonomic devices, few studies have examined their effectiveness in the healthcare workplace. METHODS: This study evaluated a statewide program that provided ergonomic consultation and financial support for purchasing ergonomic devices, which aid in patient handling and lifting. Changes in MSD rates between baseline (1 year pre-intervention) and post-intervention (up to 2 years) periods were examined in 100 work units in 86 healthcare facilities. RESULTS: The median MSD rate decreased from 12.32 to 6.64 per 200,000 employee-hours, a decrease greater than the secular trend for the study period (1999-2003). CONCLUSIONS: This study suggests that ergonomic consultation and financial support for purchasing ergonomic equipment can be an effective intervention to reduce MSDs among healthcare workers.

Ergonomics↗

Differences among outcome measures in occupational low back pain.

The rate of recurrence in low back pain patients has been reported as high as 70%; therefore, it is believed that researchers have a poor understanding of low back pain recovery. To enhance our understanding of recovery, a large cross-sectional study was conducted to compare outcome measures of return to work, impairment of activities of daily living, pain symptoms, and functional performance probability. A total of 208 workers were examined. The percentage of workers recovered based on return to work criteria was 99% compared to 25% for impairment of activities of daily living, 17% for symptoms, and 12.5% for functional performance probability. Single functional performance measures of range of motion, velocity, and acceleration had recovery rates of 59, 13, and 10%, respectively. It appears that all these criteria are measuring very different parameters of low back pain recovery. The residual loss in functional performance may indicate a decreased tolerance to physical demand providing potential insight for why recurrent low back pain rates are high.

Activities of Daily Living↗

Sagittal plane moment arms of the female lumbar region rectus abdominis in an upright neutral torso posture.

BACKGROUND: Prior imaging studies of torso muscle moment arms for use as inputs into biomechanical models have been derived from subjects lying supine. Recent research suggests moment arms of the rectus abdominis are larger when standing versus lying supine. METHODS: Axial MRI images, through and parallel to the intervertebral discs were obtained from five females in a standing upright neutral posture. Digitizing software was utilized to quantify the distance in the sagittal plane between the centroids of the intervertebral disc and the rectus abdominis muscle, and converted to the transverse plane to allow comparisons with studies with subjects in a supine posture. FINDINGS: The mean sagittal plane moment arms in the transverse plane were 9.7, 9.1, 8.5, 8.5 and 9.8 cm at the L(1)/L(2), L(2)/L(3), L(3)/L(4), L(4)/L(5) and L(5)/S(1) intervertebral levels, respectively. Compared with a study on females of a similar age group, the moment arms from this study were larger at each level, increasing from 7.3% larger at L(1)/L(2) to 43.7% larger at L(5)/S(1). INTERPRETATION: Accurate anatomical geometrical representation in biomechanical models is necessary for valid estimates of internal loading. Sagittal plane rectus abdominis moment arms were larger from the upright neutral torso posture in this study compared to studies with subjects lying supine. This suggests the torso internal moment generating capability would be represented differently in biomechanical models that use data from studies where subjects were upright, which is more reflective of the postures biomechanical models are utilized for, than when using anatomical geometry derived from supine postures.

Abdomen↗

Workplace design guidelines for asymptomatic vs. low-back-injured workers.

While numerous efforts have attempted to provide quantitative guidelines for the prevention of initial low back disorders during material handling tasks, none have appeared in the literature that address the issue of recurrent low back disorders due to materials handling when returning to the workplace. A study comparing the spine loads of low back pain patients and asymptomatic controls was conducted. Subjects lifted weights varying from 4.5-11.4 kg at four vertical heights, two horizontal distances and five task asymmetries collectively representing common industrial lifting situations. Spine loading was calculated using a validated EMG-assisted biomechanical model. Spine loads observed during lifting tasks were compared to spine tolerance values believed to initiate low back injuries. In addition, the percentage of patients successfully performing the lift was noted and used as an indication of the willingness of the subject to perform the task. These evaluations are summarized in a series of three lifting guidelines indicating safe, medium risk and high risk lifting tasks for low back patients as well as asymptomatic workers. It is believed that adherence to these guidelines can minimize the risk of recurrent low back disorders due to occupational lifting.

Back Injuries↗

The influence of individual low back health status on workplace trunk kinematics and risk of low back disorder.

A case-control study was conducted to determine whether or not kinematic-based low back disorder risk measurement (Marras et al. 1993) of the job was significantly different for those workers suffering from recent low back injuries compared to asymptomatic controls. Two hundred low back injured workers returning to full duty work and 200 asymptomatic controls were evaluated while performing the same job. There were no statistically significant differences between the two groups on any trunk motion measures or workplace measures. Therefore, job design is dictating the kinematic motions of the torso and not the worker's low back health. In addition, there was not a significant difference in job risk estimates using the lumbar motion monitor risk model. The mean risk (and standard deviation) for the low back injured group and the asymptomatic controls was 0.502 (0.178) and 0.501 (0.193), respectively. This study suggests that trunk kinematics and subsequent risk estimates are dictated primarily by job design and not influenced by the low back health status of the worker.

Adult↗

Differences in motor recruitment and resulting kinematics between low back pain patients and asymptomatic participants during lifting exertions.

BACKGROUND: Low back disorders are a prevalent problem in society today and may lead to chronic debilitating low back pain. Developing our understanding of temporal muscle and kinematic patterns during manual material handling tasks may provide insight for preventing the cascading series of events leading to chronic low back pain. METHODS: Sixty-two low back pain patients and 61 asymptomatic participants performed a variety of lifting exertions that varied in lift origin horizontal and vertical distance, lift asymmetry, and weight. Electromyographic activity of 10 trunk muscles as well as trunk and pelvic kinematics was recorded during each exertion. Differences in muscle activation and kinematic parameters were compared between low back pain patients and asymptomatic participants as a function of experimental conditions. FINDINGS: Both the left and right erector spinae activated significantly earlier and were on significantly longer in low back pain patients compared to asymptomatic participants. The horizontal and vertical location of the lift influenced the EMG and kinematic differences between the low back pain patients and asymptomatic participants. INTERPRETATION: These finding indicate that low back pain patients would be exposed to increase muscle activity resulting in higher spine loads for a greater length of time compared to asymptomatic participants. The longer exposure time to increased spine load may lead to greater risk of future low back injury and cascading events leading to debilitating low back pain. The longer muscle activation time suggests that low back pain patients have changed their motor program from an open to a closed loop system.

Adult↗

A neuro-fuzzy model for estimating electromyographical activity of trunk muscles due to manual lifting.

The main objective of this study was to develop a hybrid neuro-fuzzy system for estimating the magnitude of EMG responses of 10 trunk muscles based on two lifting task variables (trunk velocity and trunk moment) as model inputs. The input and output variables were represented using the fuzzy membership functions. The initial fuzzy rules were generated by the neural network using true EMG data. Two different laboratory-derived EMG data sets were used for model development and validation, respectively. The mean absolute error (MAE) between the actual and model-estimated normalized EMG values was calculated. Across all muscles, the average value of MAE was 8.43% (SD=2.87%) of the normalized EMG data. The larger absolute errors occurred in the left side of the trunk, which exhibited higher levels of muscular activity. Overall, the developed model was capable of estimating the normalized EMG values with average value of the mean absolute differences of 6.4%. It was hypothesized that model performance could be improved by increasing the number of inputs, including additional task variables as well as the subjects' characteristics.

Biomechanical Phenomena↗

The impact of mental processing and pacing on spine loading: 2002 Volvo Award in biomechanics.

STUDY DESIGN: The impact of various levels of mental processing and pacing (during lifting) on spine loading was monitored under laboratory conditions. OBJECTIVES: To explore how mental demands and pacing influence the biomechanical response and subsequent spine loading and, to determine whether individual characteristics have a modifying role in the responses. SUMMARY OF BACKGROUND DATA: Modern work often requires rapid physical exertions along with demands of mental processing (both psychosocial stressors). While the effect of physical workplace factors on spine loading has been widely documented, few studies have investigated the impact that interaction of psychosocial factors and individual factors has on spine loads. METHODS: For this study, 60 subjects lifted boxes while completing two types of mental processing tasks: 1) series tasks with decisions occurring before the act of lifting, and 2) simultaneous tasks with decisions occurring concurrently with the lift. For both of these mental processing conditions, two intensities of mental load were evaluated: simple and complex. Task pacing was also adjusted under slow and fast conditions. Finally, individual characteristics (personality and gender) were evaluated as potential modifiers. An electromyographically assisted model evaluated the three-dimensional spine loads under the experimental conditions. RESULTS: Simultaneous mental processing had the largest impact on the spine loads, with the complex intensity resulting in increases of 160 N with lateral shear, 80 N with anteroposterior shear, and 700 N with compression. Increased task pace produced greater lateral shear (by 20 N), anteroposterior shear (by 60 N), and compression loads (by 410 N). Gender and personality also influenced loadings by as much as 17%. CONCLUSIONS: Mental processing stress acted as a catalyst for the biomechanical responses, leading to intensified spine loading. Mental stress appeared to occur as a function of time pressures on task performance and resulted in less controlled movements and increases in trunk muscle coactivation. These adjustments significantly increased spine loading. These results suggest a potential mechanism for the increase in low back pain risk resulting from psychosocial stress caused by modern work demands.

Adult↗

Spine loading as a function of gender.

STUDY DESIGN: In vivo laboratory studies were conducted to investigate the spine loads imposed on men and women during a series of lifting tasks that varied in the degree of lifting control required by the subject. OBJECTIVE: To identify and understand differences in spine loading and musculoskeletal control strategies between men and women performing lifts of varying task complexity. SUMMARY OF BACKGROUND DATA: Few studies have examined differences in spine loading as a function of individual factors such as subject gender. Furthermore, no biomechanical studies have attempted to quantify and understand how differences in anthropometry between genders might influence muscle recruitment and subsequent spine loads. Because the modern workplace seldom discriminates between genders in job assignments, it is important to understand how differences in spine loading and potential low back disorder risk might be associated with gender differences. METHODS: For this study, 140 subjects participated in two separate experiments requiring different degrees of musculoskeletal motion control during sagittal plane lifting. The two experiments consisted of 35 men and 35 women performing lifts in which motion was isolated to the torso and 35 men and 35 women completing whole-body free-dynamic whole body lifts. An electromyography-assisted model was used to evaluate spine loading under these conditions. RESULTS: Absolute spine compression generally was greater for the men. Under the highly controlled (isolated torso) conditions, most differences were attributed solely to differences in body mass. Under a whole-body free-dynamic condition, significant differences in muscle coactivations resulted in greater relative compression and anterior-posterior shear spine loading for the women. CONCLUSIONS: Differences in spine loadings as a function of gender under the more controlled lifting conditions were primarily a function of different body masses. However, loading pattern differences existed between the genders under whole-body free-dynamic conditions as a result of kinematic compensations and increases in muscle cocontraction, with women generally experiencing greater relative loads. When spine tolerance differences are considered, one would expect that females would be at greater risk of musculoskeletal overload during lifting tasks.

Abdomen↗

Effects of posture on dynamic back loading during a cable lifting task.

This study evaluated spinal loads associated with lifting and hanging heavy mining cable in a variety of postures. This electrical cable can weigh up to 10 kg per metre and is often lifted in restricted spaces in underground coal mines. Seven male subjects performed eight cable lifting and hanging tasks, while trunk kinematic data and trunk muscle electromyograms (EMGs) were obtained. The eight tasks were combinations of four postures (standing, stooping, kneeling on one knee, or kneeling on both knees) and two levels of cable load (0 N or 100 N load added to the existing cable weight). An EMG-assisted model was used to calculate forces and moments acting on the lumbar spine. A two-way split-plot ANOVA showed that increased load (p < 0.05) and changes in lifting posture (p < 0.05) independently affected trunk muscle recruitment and spinal loading. The increase in cable load resulted in higher EMG activity of all trunk muscles and increased axial and lateral bending moments on the spine (p < 0.05). Changes in posture caused more selective adjustments in muscle recruitment and affected the sagittal plane moment (p < 0.05). Despite the more selective nature of trunk EMG changes due to posture, the magnitude of changes in spinal loading was often quite dramatic. However, average compression values exceeded 3400 N for all cable lifting tasks.

Adult↗

Evaluation of spinal loading during lowering and lifting.

OBJECTIVE: To estimate the three-dimensional spinal loads during various lifting and lowering tasks. DESIGN: The in vivo measurements of the trunk dynamics, moments, and myoelectric activity were used as inputs into an electromyographic-assisted model used to predict the three-dimensional spinal loads. BACKGROUND: Previous studies of eccentric motions have investigated muscle activity, trunk strength, and trunk moments. A void in the body of knowledge exists in that none of these studies investigated spinal loading. METHODS: Ten subjects lifted (40 degrees of flexion to 0 degrees ) and lowered (0 degrees of flexion to 40 degrees ) boxes while positioned in a structure that restrained the pelvis and hips. The tasks were performed under isokinetic trunk velocities of 5, 10, 20, 40, and 80 deg s(-1) while holding a box with weights of 9.1, 18.2, and 27.3 kg. RESULTS: Lowering strength was found to be 56% greater than lifting strength. The lowering tasks produced significantly higher compression forces but lower anterior-posterior shear forces than the lifting tasks. The differences in the spinal loads produced by the two lifting tasks were attributed to differences in coactivity and unequal lifting moments (i.e. holding the box farther away from the body). CONCLUSIONS: The nature of the spinal loads that occur during lowering and lifting were significantly different. The difference in spinal loads may be explained by different lifting styles.

Journal Article↗

Revised protocol for the kinematic assessment of impairment.

BACKGROUND CONTEXT: Marras et al. developed a functional motion performance tool that accurately identified impaired low back motion performance, with sensitivity of 90% and specificity of 94%. However, the protocol required testing of five controlled tasks and was relatively time consuming. PURPOSE: To determine whether a more time-efficient low back motion functional performance evaluation tool with acceptably high sensitivity and specificity could be developed. STUDY DESIGN/SETTING: Low back functional motion (kinematic) performance evaluations were completed on two groups, consisting of controls (no history of back pain) and low back pain patients. A second low back pain population was also evaluated prospectively to assess recovery. PATIENT SAMPLE: The study population consisted of 335 patients and 374 controls. Thirty acute low back pain patients were monitored prospectively. OUTCOME MEASURES: Kinematic low back functional performance measures. METHODS: Low back motion functional performance was measured using the lumbar motion monitor. A revised discriminant function model was developed using data from only one of the five original functional motion performance control tasks. Prospective study data were used to track differences in recovery time between the revised and original discriminant function models. RESULTS: The revised model using functional motion performance from the controlled sagittally symmetric task had a sensitivity of 90% and specificity of 92%. When comparing the revised and original model results, the time to recovery was the same in 90% of cases. CONCLUSIONS: The revised (more time efficient) testing procedure yielded high sensitivity and specificity.

Adult↗

Changes in spine loading patterns throughout the workday as a function of experience, lift frequency, and personality.

BACKGROUND CONTEXT: Psychosocial stressors have been associated with low back pain reporting. However, response to psychosocial risk factors may be dependent on the individual's personality type that, in turn, can affect muscle recruitment and spine loading. This study explores how personality might be associated with spine loading during repetitive lifting performed throughout an entire work shift. PURPOSE: Assess spine loading as a function of an individual's personality type during repetitive, long-term exposure to a materials handling tasks. STUDY DESIGN: Laboratory experiment where experienced and inexperienced participants performed repetitive, asymmetric lifts at various load and lift frequency levels throughout a series of 8-hour exposure periods. Spine loads were monitored throughout the work period. PATIENT SAMPLE: Twelve novice and 12 experienced materials handlers who were asymptomatic for back pain. OUTCOME MEASURES: Spine compression, anterior-posterior (A/P) shear, and lateral shear at the L5-S1 level. METHODS: Participants were categorized into personality types based upon the Myers-Briggs personality type indicator. An electromyography-assisted biomechanical model was used to assess spine compression, A/P shear, and lateral shear throughout the exposure period. RESULTS: The results indicate that intuitors had higher shear spinal loading regardless of moment exposure, lift frequency, and time through the work period, compared with the sensor personality type. In addition, higher spine compressive and shear forces occurred in the perceiver personality compared with the judgers' personality trait, regardless of moment and, often, lift frequency. Novice lifters typically experienced greater spine loading. CONCLUSIONS: The results suggest that when there exists a personality-job environment mismatch, spinal loading increases via an increase in antagonistic co-contraction. The trends suggest that inherent personality characteristics may play a role in one's motor control strategies when performing a repetitive lifting task.

Adult↗