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Biomedical subjects

Wojciech Jedrzejewski

Publications and source records attributed to Wojciech Jedrzejewski.

6 recordsLinked to original sources

[Intraorbital foreign body--three years follow-up].

A case of patient with metallic intraorbital foreign body, was described. The foreign body went trough the eye and finally was situated close to the optic nerve. After three years, no signs of siderosis were found (ERG). The patient is still under control.

Adult↗

[Sudden blindness of 11-year old boy in the course of acute lymphoblastic leukemia].

PURPOSE: The aim of this study is to present dramatic ocular manifestation of acute lymphoblastic leukemia. MATERIAL AND METHODS: The 11 years old boy was hospitalized due to acute leukemia at the Department and Clinic of Pediatric Hematology, and was referred to ophthalmic examination because of sudden blindness of the right eye. General ophthalmic examination and electrophysiological tests were done. RESULTS: No light perception of right eye, and markedly reduced visual evoked responses were caused by infiltration with great edema in optic nerve and its surrounding of retina. In spite of the fact, that the infiltrations disappeared after general therapy, the vision did not recover at all. CONCLUSIONS: Even intensive treatment may be ineffective in blindness prevention in severe course of acute leukemia.

Blindness↗

[Optic disc drusen and glaucoma--case report].

Optic disc drusen make examination towards glaucoma difficult to interpret. They change nerve head morphology and visual field defects can resembling glaucomatous damage. Patient with strong headache was examined and we found drusen on both optic nerve heads and intraocular pressure about 27 mmHg. Visual fields demonstrated scotomas--in lower half and the enlargement of the blind spot. After topical treatment and intraocular pressure normalization, the patient's complaints had gone. Control examination after one year revealed progression of visual field changes. Electrophysiological examination showed abnormalities typical for glaucoma.

Adolescent↗

[The intracranial hypertension in the course of Arnold-Chiari malformation].

PURPOSE: The aim of this study was to remind the symptoms and diagnostic methods helpful to recognize Arnold Chiari syndrome. MATERIAL AND METHODS: We have presented a 53-year-old woman with papilledema who was operated and treated oncologically because of right breast tumor - four years ago. As a result of diagnostic research which took into consideration a brain magnetic resonance imaging (MRI), the suspicion of metastatic cerebral tumor was excluded and Arnold - Chiari malformation was diagnosed. CONCLUSIONS: The intracranial hypertension and it's ocular manifestation - papilloedema may be caused by different, also congenital, reasons. The brain MRI is the mainly procedure to diagnose the Arnold - Chiari malformation.

Arnold-Chiari Malformation↗

[Acute endophthalmitis of 15-year old boy in the course of acute lymphoblastic leukemia--part I].

PURPOSE: The aim of this study is to present dramatic ocular manifestation of acute lymphoblastic leukemia. MATERIAL AND METHODS: 15-year old boy was hospitalized due to acute leukemia at the Department and Clinic of Pediatric Hematology and was referred to ophthalmologist because of strong pain and decreased visual acuity of the left eye. General ophthalmic examination and electrophysiology were done. These procedures were repeated after 1, 2, 5 and 11 weeks and also after 6 and 9 months. RESULTS: Acute uveitis with cellular exudation to the vitreous, papilledema, swelling of the macula and green-yellowish infiltration which elevated the temporal part of the retina, were noticed. Swelling of the iris and miosis were observed. After one week of local anti-inflammatory treatment the eye became painless with little deep injection only. Simultaneously causal treatment of basic disease was continued. Control examinations revealed step by step improvement of ocular changes. After 6 months in the place of retinal infiltration choroidoretinal atrophy was seen. The functional deficits in visual field and electrophysiological examinations were found, too. One year later, the patient came again because of recurrence. Involvement of the central nervous system with signs of meningitis occurred. Visual acuity was normal and no infiltration of eyes was found, but there was papilledema in both eyes. CONCLUSIONS: In acute leukemia ocular manifestation may be highly expressed. The patients require local symptomatic and general causal treatment in cooperation of ophthalmologist with hematologist.

Acute Disease↗