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Biomedical subjects

Wojciech Zajecki

Publications and source records attributed to Wojciech Zajecki.

7 recordsLinked to original sources

[Rare case of palatal amyloidosis].

Amyloidosis first described by Karl Rokitansky in 1842 consists in accumulation of pathological protein (amyloid) within both cells and extracellular space. It usually develops in the course of a chronic inflammation or some neoplasms. The clinical picture depends on the impairment degree of an organ in which amyloid accumulates. The diagnosis is based on the cytological examination of the material collected by means of biopsy of the subcutaneous fatty tissue and of the mucosa of the anal orifice, gums, kidneys or liver etc. In the presented study a rare case of amyloidal concrements localised in the palatal region has been described. Literature has usually presented amyloidosis localised in the tongue, lips, rhino-pharynx and larynx. Amyloidosis localised in the region of the head and neck occurs very rarely. In the presented case amyloidal deposition in any other site was not reported.

Amyloidosis↗

[Pyoderma gangrenosum after a pacemaker implantation--case report].

We are presenting a 71-years old male patient with chronic skin lesions that appeared at multiple site of pacemaker implantations in the upper thorax. In spite of many treatment trials, no significant improvements were accomplished. Expanded dermatological tests including serial histopathological examinations were necessarily performed. Based on test results and clinical presentations, the diagnosis of pyoderma gangrenosum was made. Immediate steroid therapy allowed dramatic improvement of the chronic inflammatory condition. The patient is still undergoing a close dermatological and cardiological follow-up. Replacement of the pacemaker into the abdomen is currently being considered.

Aged↗

[Mediastinal tumor as a cause of fetal hydrops].

Unusual case of fetal hydrops was presented. In a stillborn infant an Rh incompatibility was suspected as a cause of hydrops, although prentally an immunologic source of the illness was excluded. Post-mortem a large polycystic mediastinal teratoma with cardiac and pulmonary hypoplasia was stated as a main cause of the hydrops. Additionally, histopathological examination proved this diagnosis. The mediastinal tissue contained immature epithelial, mesenchymal and blastemal elements. The congenital teratomas should be taken for account in problematic diagnosis of complicated cases.

Adult↗

Endodermal cyst of the cervical spinal cord with associated partial fusion of the vertebrae.

A case of a 43-year-old woman with an intradural endodermal cyst at the C4 spinal cord level is presented. The lesion manifested with progressive neck pain and weakness of lower extremities. The presumptive diagnosis of extramedullary benign cystic lesion was established after MRI examination. Coexisting partial fusion of the C5-C6 vertebral bodies was found on X-ray films. The patient was cured by resection of the cyst wall, performed by laminectomy. Pathological examination revealed a cyst wall lined with ciliated cuboidal cells, resembling the respiratory epithelium. Immunohistochemistry demonstrated cytokeratin and epithelial membrane antigen expression in the lining of the cyst. Endodermal cyst should be considered in the differential diagnosis of intraspinal cystic lesions, especially those associated with vertebral anomalies.

Adult↗

[Glomus tumor of the thumb].

The article presents a case of 42-year-old patient with Recklinghausen disease treated in the outpatient clinic for 5 years for hyperaesthesia of a thumb. On physical examination the thumb was painful but smooth, soft with no features of infection. Neuralgia and Raynaud syndrome were suspected. Additional investigations did not show significant abnormalities, however, successive forms of conservative treatment (including denervation of the thumb) were not successful. Instant, persistent pain caused by even a slight touch or thermal changes suggested glomus tumor of the thumb. Physical examination did not confirm a lump typical in this disease. Finally partial resection of the digital pulp was performed, which led to complete recovery. Histopathological examination confirmed glomus tumor of the thumb.

Adult↗

[Coexistence of pigmented urticaria and mastocytomas: a case report].

Mastocytoses are a heterogeneous group of disorders of unknown etiology characterised by the accumulation of mast cells, particularly in the skin. Mastocytosis may be limited to the skin or involve internal organs, especially those playing the lymphoreticular function. We present a case of 9-year-old girl, with a history of maculopapules at the age of two, followed by yellow-brownish, nodular skin lesions. The skin lesions, located on the trunk, neck and face were accompanied by pruritus. The histopathological examination of the node confirmed the diagnosis of mastocytoma. A bone scintigram showed an increased uptake of radiotechnetium around the right coxal region. Application of antihistaminic drugs and phototherapy (UVA) has led to partial remission of skin manifestations of the disease. A long-term follow-up of the child is necessary.

Child↗

[Two cases of bronchial tuberculosis--diagnostic difficulties].

We present two cases of bronchial tuberculosis. The first one, man aged 45, showed diffuse necrotic changes in bronchoscopic picture described histologically as coagulative necrosis. AFB were not found in sputum smear but only in the cultures. The second patient--19-year old female presented the features of right lung bronchopneumonia. Bronchoscopic examinations showed diffused necrotic infiltration. Tuberculosis etiology was confirmed by positive results of examined brosage, concomitantly with negative Mantoux reaction.

Adult↗