Total synthesis of IKD-8344.
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Anti-Bacterial Agents↗
Biomedical subjects
Woo Han Kim
Publications and source records attributed to Woo Han Kim.
Feigrisolide C: structural revision and synthesis.
[Carbohydrate structure: see text] The original macrodiolide structure proposed for feigrisolide C was incorrect. The true structure of feigrisolide C was identified as (2'S,3'S,6'R,8'R)-homononactoyl (2R,3R,6S,8S)-nonactic acid, which was confirmed by total synthesis.
Anti-Bacterial Agents↗
Synthesis of the proposed structure of feigrisolide C.
[reaction: see text] Possible structures of feigrisolide C were synthesized via ring-closing olefin metathesis reaction of a diester derivative prepared from 8-epi-nonactic acid, but physical characteristics of the synthetic samples did not match with those of the natural sample of feigrisolide C.
Cyclization↗