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X Castells

Publications and source records attributed to X Castells.

24 records · Page 2Linked to original sources

Risk adjustment: beyond patient classification systems.

UNLABELLED: Diagnosis related groups (DRGs) are widely used in several countries. Their various versions aim to value the cost of hospital production. In Europe, the patient classification systems and standard weights used are usually the American originals. OBJECTIVES: The objective of this study was to analyse the extent to which DRGs and DRG-weights explain patient cost variability. Different components of patient cost (severity, comorbidities, complications and socioeconomic status), which are not well explained by DRG and which can be approximated by using administrative data, were also analysed. METHODS: A total of 35,262 discharges from two public hospitals in Barcelona were analysed. The Health Care Financing Administration (HCFA)-DRGs and the All Patient Refined (APR)- DRGs were calculated. Severity was adjusted by Disease Staging, and comorbidities and complications were calculated using Elixhauser and Charlson comorbidities groupings. An ecological socioeconomic status indicator was used. Linear regressions were estimated to explain per-patient cost variability. RESULTS: We found that Medicare's DRG-weights explained only 19% of cost variability. Cost-based weights explained nearly 40% (38-42%, depending on the DRG classification used). Exclusion of outliers increased explanatory power to R² = 47-48%. The remaining adjustment variables increased R² to 49-51%. DISCUSSION: Medicare's DRG-weights are not well-suited to Europe. Cost-based DRG-weights and outlier trimming have significantly greater explanatory power. The remaining clinical and socioeconomic variables have considerably less explanatory power but were statistically significant and behaved as expected. Spanish and other European health authorities should adapt DRG-classification systems to their environments for use in hospital production cost valuation.

Diagnosis-Related Groups↗

[Profile of the hospital case mix of the immigrant population in Barcelona, Spain].

OBJECTIVE: Although the immigrant population in cities such as Barcelona has tripled in the last five years, until now the impact of this group on the health system has not been rigorously evaluated. The aim of this study was to compare hospital resource utilization among the immigrant population with that among the native population through case mix, demographic characteristics and hospital day use. MATERIAL AMD METHODS: We analyzed 15,057 discharges from Hospital del Mar in Barcelona in 2000. This hospital attends 60% of admissions from the Ciutat Vella district. In 2000, 21% of the population of this district were immigrants. Socio-demographic patient characteristics and case mix were compared between the immigrant and the native population. Hospital resource use was compared according to age, case mix (diagnosis related groups) and seriousness (severity, complications and comorbidities) of the events requiring medical care. RESULTS: The case mix of the immigrant population differed from that of the autochthonous population due to pronounced ge differences and a higher fertility rate. Thirty-three percent of immigrant admissions were for deliveries. The mean cost of discharge of immigrants from low-income countries was 30% lower than that for the remaining discharges. After adjusting for age, case mix and severity, length of stay among the immigrant population was significantly shorter. A 5% reduction was found after adjusting for case mix and a 10% reduction was found when all the factors were considered. CONCLUSIONS: Case mix differences are due to age and socio-cultural factors. Immigrants are rejuvenating the ageing native population and the role of gynecology-obstetrics and pediatrics needs to be increased. The finding that resource use per discharge is lower among immigrants from low-income countries contradicts the expectation that lower socioeconomic status leads to higher hospital resource use intensity. Therefore, new hypotheses and analyses that explain this situation should be put forward.

Adolescent↗

[The evidence on breast cancer screening: the story continues].

The publication of the new Cochrane review on screening for breast cancer with mamography has revived the debate on breats screening and raised some new topics. Whereas the Cochrane reviewers reasserted on their previous conclusion of the lack of efficacy of breast screening, the new review of the Swedish studies, the new systematic review of the Agency for Healthcare Research and Quality commissioned by the US Preventive Services Task Force, and the recent review of an IARC working group supported the efficacy of breast screening after carefully considering the methodological quality of trials. Nevertheless, the efficacy of breast screening for younger women remains controversial. The present controversy has raised other issues like the measure of the benefit in screening trials or the potential adverse effects of screening, particularly, overdiagnosis and its impact on therapy that are discussed in this papers. It also stresses of evaluating screening before introducing it and the need to inform the population about the benefits and the potential harms and about uncertainties about cancer screening.

Breast Neoplasms↗

[Consumption and cost of antipsychotic drugs].

INTRODUCTION: In recent years, new atypical antipsychotic drugs have been marketed. This study aims to analyze the evolution of the consumption pattern and pharmaceutical cost of the antipsychotic drugs during the last years and the impact that the new atypical antipsychotic drugs have had. METHODS: Based on the ECOM database of the Ministry of Health and Consumer Affairs of Spain, the sales data of the antipsychotic drugs in Catalonia during the 1990-2001 period have been chosen. The drugs have been classified into typical or classical and atypical. Consumption data have been expressed in daily defined dose (DDD) per 1,000 inhabitants and per day of treatment (DID), and cost data in constant euros. RESULTS: Antipsychotic consumption increased from 3.31 DID in 1990 to 6.04 DID in 2001. Typical drugs consumption decreased (from 100 % consumption in 1990 to 46 % in 2001) and that of the atypical ones increased (from 1% consumption in the year 1993 to 54% in the year 2001). A change in the use pattern of different drugs is verified. In the year 1990, the most consumed drugs were flupenthixol (0.86 DID) and haloperidol (0.67 DID), and in the year 2001 olanzapine (1.69 DID) and risperidone (1.30 DID). The drugs with a greater increase in consumption were olanzapine, which multiplied its consumption five fold from 1997 to 2001 and risperidone, which multiplied it by 20 from 1994 to 2001. During the study period, the cost increased 13 times, above all due to increase in cost of atypical antipsychotics (from less than 1 % of the total cost in 1993 to 92 % of the total cost in 2001). The DDD cost of antipsychotics increased (6.48 euros in 1990 and 20.31 euros in 2001). However, that of the typical antipsychotics decreased (6.48 euros in 1990 and 4.62 euros in 2001) and that of the atypical ones increased (2.06 euros in 1993 and 15.69 euros in 2001). CONCLUSION: The marketing of the new atypical antipsychotic drugs has had an extraordinary impact on antipsychotic drug consumption and cost. The cost/effectiveness ratio of the new atypical antipsychotic drugs in the clinical practice should be evaluated to determine the economic resources aimed at costs of the different antipsychotic drugs.

Antipsychotic Agents↗

[Agreement in the determination of electrolytes in samples of serum and plasma. Stability of these samples kept for 2 hours at room temperature with uncovered tubes].

UNLABELLED: The determination of electrolytes in the clinical laboratories is carried out in samples of serum or plasma in situations that tubes remain open during a lingering time. OBJECTIVE: To estimate the agreement and the interchangeability in the determination of electrolytes for three types of tubes (serum with separator, plasma with and without separator) in samples that remain at room temperature and open up to two hours. MATERIAL AND METHODS: Samples of 36 voluntary patients were selected determining the levels of sodium, potassium, chlorine, calcium, magnesium and phosphate in the three tubes on time 0 (basal), 60 and 120 minutes. The agreement was estimated by means of the intraclass correlation coefficient (ICC) and the interchangeability of results by means of lineal regression. RESULTS: Agreement among the samples was very high with ICC higher than 0.9 in all basal determinations except for the potassium for which the presence of a constant systematic error was detected between serum and two tubes of plasma. The stability of the parameters is good in all the samples. CONCLUSIONS: It is possible the use of different types of tubes in the determination of electrolytes under the working conditions of the clinical laboratories. The determination of potassium needs to be corrected before the exchange of results obtained with serum and plasma. The stability in the two first hours is good in all the cases.

Blood Chemical Analysis↗