PubMed Health⌕ Search

Biomedical subjects

X Marchandise

Publications and source records attributed to X Marchandise.

131 records · Page 8Linked to original sources
PubMedDate not supplied

[Simultaneous scintigraphy exploration using MDP - 99 Tc and 67GA in infectious osteoarticular pathology. Initial results].

A new investigation in infectious osteoarticular pathology is presented, involving the use of two tracers: one for bone metabolism (MDP - 99mTc), the other for the infectious process (67Ga). The initial results of a prospective study of 72 scintigraphic examinations are reported. Analysis of the results reveals the value in using 67Ga to determine the stage of development of the lesion and consequently to adapt the treatment. Classical bone scintigraphy, whose value remains the early detection of signs compared to radiography, does not allow us to follow the course of the lesion over time. The need to combine scintigraphic techniques has already been recognised (Lisbona, Gaucher) but there has usually been sequential meaning, apart from the risk of false negatives (early osteitis), repeated visits by the patients over a period of time. The simultaneous use of 2 tracers, technically possible, avoids these problems and produces a rapid result (generally 6 hours after the injection).

Arthritis↗
PubMedDate not supplied

[Serial and static brain radioangiogram in diagnosis of carotid disease: value, indication and limits by comparative study with EEG, Doppler study and cerebral arteriography (author's transl)].

Value, indication and limits of serial and static brain radioangiogram in carotid disease are studied comparatively with EEG, Doppler study and cerebral arteriography. The isotopic study shows the occlusion and its consequences on middle cerebral artery and cerebral hemisphere. The "Hot-Nose" sign is rarely seen, but then with large focal abnormalities. In 20% of studied cases, isotopic study provides information about the efficiency of suppleance circulation or the existence of a blood derivation. The value of serial and static scintigraphy deserves it a better place among the non invasive diagnosis method of carotid disease.

Adult↗
PubMedDate not supplied

Evaluation of bone mineral density in patients with rheumatoid arthritis. Influence of disease activity and glucocorticoid therapy.

OBJECTIVES: To study bone mass and the factors that influence bone mass in rheumatoid arthritis patients versus controls. PATIENTS AND METHODS: 85 patients (73 women) with a mean age of 57 +/- 11 years and a mean disease duration of 13 +/- 9 years were compared to 85 age- and sex-matched controls. Among the patients, 62 (76%) had positive rheumatoid factor tests and 51 (60%) were receiving steroid therapy, with a mean daily dose of 10 +/- 4 mg and a mean duration of 7 +/- 6 years. The following parameters were determined: morning stiffness duration, painful and swollen joint counts, Lee's and Ritchie's indices, Health Assessment Questionnaire score, erythrocyte sedimentation rate, and C-reactive protein. Bone mineral density was measured at the lumbar spine and femoral neck using dual-energy X-ray absorptiometry (Sophos L-XRA). RESULTS: In the nonsteroid-treated patients, bone mineral density was similar to that in controls at the lumbar spine but was decreased by 8% (95% confidence interval [CI], 1.8-14.2%) at the femoral neck (0.76 +/- 0.14 g/cm2 versus 0.83 +/- 0.15 g/cm2; P = 0.03). Decreases of 11.5% (95% CI, 8.1-14.9%) at the lumbar spine and 10.4% (95% CI, 6.4-14.4%) at the femoral neck were found in the steroid-treated patients versus the nonsteroid-treated patients. In the patient group, femoral neck bone mineral density was significantly negatively correlated with age (r = -0.5), the Heath Assessment Questionnaire score (r = -0.27), and the erythrocyte sedimentation rate (r = -0.25), whereas only the first two variables were significantly correlated with lumbar bone mineral density. A multiple linear regression model including age, glucocorticoid use, rheumatoid factor, the Health Assessment Questionnaire score, and the erythrocyte sedimentation rate was constructed and adjusted for the number of variables. This model explained 44.7% of the variance of femoral neck bone mineral density. CONCLUSION: Rheumatoid arthritis is associated with a decrease in bone mass that is most marked in patients with active and/or severe disease and in those who take glucocorticoids.

Absorptiometry, Photon↗